17 Questions
What is the term for a substance that mimics the behavior of acetylcholine at one or more of the body's acetylcholine receptors?
Cholinomimetic drug
Which of the following is NOT a muscarinic receptor?
M6
What is the enzyme responsible for the biosynthesis of acetylcholine?
Choline acetyl transferase
Which of the following is an example of a cholinergic antagonist?
Atropine
What is the term for a receptor that uses acetylcholine as its neurotransmitter?
Cholinergic receptor
Who shared the Nobel prize in Physiology or Medicine in 1936 for their studies of acetylcholine and nerve impulses?
H.H.Dale and O.Loewi
What is the primary mechanism of action of indirect cholinomimetics?
Inhibiting acetyl cholinesterase and butyryl cholinesterase
Which of the following cholinergic agonists can be given orally?
Bethanechol
What is the effect of introducing a methyl group on the ethylene bridge of a cholinergic agonist?
Increased muscarinic receptor selectivity
What is the primary difference between reversible and irreversible acetylcholinesterase inhibitors?
Reversible inhibitors are used in medicine, while irreversible inhibitors are used in insecticides
What is the role of acetylcholinesterase in the synapse?
To break down acetylcholine
What is the primary function of cholinergic agonists?
To bind to cholinergic receptors
What is the primary function of cholinesterase reactivator in cholinergic drugs?
To reactivate acetylcholine esterase
Which of the following cholinomimetic agents is a direct acting agent?
Carbachol
What is the role of acetylcholine in biosynthesis?
To transmit nerve impulses
Which of the following is NOT a type of cholinergic receptor?
Adrenergic receptors
What is the effect of cholinergic blocking agents on acetylcholine?
They block the release of acetylcholine
This quiz covers cholinergic antagonists, including natural and synthetic agents, as well as the biosynthesis and catabolism of acetylcholine and cholinergic receptors.
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