Cholinergic and Adrenergic Agents in Glaucoma
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Questions and Answers

What is the primary action of cholinergic agents like pilocarpine in the treatment of glaucoma?

  • Decrease intraocular pressure by constricting the pupil (correct)
  • Cause systemic hypertension
  • Dilate the pupil to enhance fluid absorption
  • Increase production of aqueous humor

Which of the following is a consideration when using beta blockers for glaucoma?

  • They do not affect heart rate or blood pressure.
  • They may cause bronchoconstriction in patients with asthma. (correct)
  • They should be the first choice for all glaucoma patients.
  • They are safe for all diabetic patients without restrictions.

What side effect may occur with the use of prostaglandin analogs over a long period?

  • Severe allergic reactions
  • Increased pupil dilation
  • Temporary blindness
  • Iris color change to darker shades (correct)

Which drug class is considered first-line therapy for reducing intraocular pressure in glaucoma?

<p>Beta blockers (C)</p> Signup and view all the answers

What is a key nursing action prior to administering carbonic anhydrase inhibitors?

<p>Ask about a sulfa allergy (D)</p> Signup and view all the answers

What are common activities to avoid after glaucoma surgery to prevent increased intraocular pressure (IOP)?

<p>Bending over at the waist (A)</p> Signup and view all the answers

How often should individuals aged 40 to 54 have glaucoma checks to screen for potential issues?

<p>Every 1 to 3 years (D)</p> Signup and view all the answers

Which symptom should be reported immediately by a patient after glaucoma surgery?

<p>Lid swelling (B)</p> Signup and view all the answers

What action should be taken if a patient experiences pain accompanied by nausea or vomiting after glaucoma surgery?

<p>Report it as it may indicate increased IOP or hemorrhage (B)</p> Signup and view all the answers

What is a potential consequence of untreated glaucoma?

<p>Blindness (B)</p> Signup and view all the answers

Flashcards

Miotics

Medications that constrict the pupil.

IOP reduction - Beta-blockers

Lower intraocular pressure by decreasing aqueous humor production.

Carbonic anhydrase inhibitors

Reduce intraocular pressure by decreasing aqueous humor production.

Prostaglandin analogs

Increase outflow of aqueous humor by dilating vessels.

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IV Mannitol

Osmotic diuretic used to quickly decrease IOP in acute angle-closure glaucoma.

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Glaucoma Surgery

Procedures like laser trabeculectomy, iridotomy, or shunt placement to improve aqueous humor flow by creating an outflow channel.

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Post-Surgery Instructions

Avoid activities that increase IOP, such as bending, coughing, straining, head hyperflexion, restrictive clothing, and sexual intercourse.

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Post-Surgery: Report These

Report any severe pain, nausea, lid swelling, decreased vision, bleeding, discharge, sharp pain, flashes of light, floating shapes, and changes in vision.

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Glaucoma: Prevent Blindness

Regular glaucoma checks can prevent irreversible blindness.

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Glaucoma Check Frequency

Frequency of checks increases with age: every 2-4 years before 40, 1-3 years between 40-54, 1-2 years between 55-64, and every 6-12 months over 65.

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Study Notes

Cholinergic Agents

  • Miotics: constrict pupils, improve aqueous humor outflow.
  • Examples: carbachol, echothiophate, pilocarpine.
  • Side effect: blurred vision.
  • Pilocarpine: second-line treatment for open-angle glaucoma (POAG).
  • Client education: use good lighting to prevent falls.

Adrenergic Agonists

  • Reduce intraocular pressure (IOP) by decreasing aqueous humor production, dilate pupils to enhance fluid flow.
  • Examples: apraclonidine, brimonidine tartrate, dipivefrin hydrochloride.
  • Client education: wear sunglasses due to pupil dilation.

Beta Blockers

  • First-line treatment for glaucoma.
  • Decrease IOP by reducing aqueous humor production.
  • Systemic absorption possible, causing bronchoconstriction and hypoglycemia.
  • Use cautiously in asthma/COPD/diabetes patients.
  • May potentiate systemic effects of oral beta-blockers, leading to bradycardia and hypotension.
  • Example: timolol.

Carbonic Anhydrase Inhibitors

  • Decrease IOP by reducing aqueous humor production.
  • Sulfa-based medications.
  • Nursing action: ask about sulfa allergies.
  • Examples: acetazolamide, dorzolamide, brinzolamide.

Prostaglandin Analogs

  • Increase uveoscleral outflow by dilating blood vessels in trabecular meshwork.
  • Examples: bimatoprost, latanoprost.
  • Client education: check for corneal abrasions before administration; long-term use may darken iris color.

Systemic Osmotics

  • IV mannitol: osmotic diuretic for emergency treatment of primary angle-closure glaucoma.
  • Quickly reduces IOP.

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Description

This quiz covers the pharmacology of cholinergic and adrenergic agents used in the treatment of glaucoma. It includes their mechanisms, examples, side effects, and important client education points. Test your knowledge on beta blockers and carbonic anhydrase inhibitors as well.

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