Cholesterol Transport
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Questions and Answers

Which lipoprotein is responsible for delivering dietary lipids to the liver?

  • VLDL
  • LDL
  • Chylomicrons (correct)
  • HDL
  • Which lipoprotein is the precursor of LDL?

  • HDL
  • Chylomicrons
  • IDL
  • VLDL (correct)
  • Which lipoprotein is associated with reverse cholesterol transport?

  • LDL
  • HDL (correct)
  • Chylomicrons
  • VLDL
  • Which lipoprotein is the most dense and smallest?

    <p>LDL</p> Signup and view all the answers

    Which lipoprotein is responsible for mediating synthesis and secretion of chylomicrons?

    <p>Apo B-48</p> Signup and view all the answers

    Which lipoprotein has the highest content of cholesterol esters?

    <p>LDL</p> Signup and view all the answers

    Which lipoprotein is associated with familial hypercholesterolemia?

    <p>LDL</p> Signup and view all the answers

    Which lipoprotein is responsible for delivering endogenous lipids to peripheral tissues?

    <p>VLDL</p> Signup and view all the answers

    Which lipoprotein is least dense and larger in size?

    <p>Chylomicrons</p> Signup and view all the answers

    Which lipoprotein is required for HDL formation and activates LCAT?

    <p>Apo A-1</p> Signup and view all the answers

    Which lipoprotein is involved in reverse cholesterol transport?

    <p>HDL</p> Signup and view all the answers

    Which lipoprotein carries the most direct relationship to atherosclerosis?

    <p>LDL</p> Signup and view all the answers

    Which lipoprotein is considered vasoprotective?

    <p>HDL</p> Signup and view all the answers

    Which lipoprotein is primarily regulated by the relative levels of circulating TG-rich lipoproteins?

    <p>IDL</p> Signup and view all the answers

    Which lipoprotein is involved in the formation of fatty streaks in atherosclerosis?

    <p>LDL</p> Signup and view all the answers

    Which lipoprotein is associated with Tangier disease when deficient?

    <p>HDL</p> Signup and view all the answers

    Which lipoprotein is activated by ApoA-I and produces the majority of CE in circulating lipoproteins?

    <p>HDL</p> Signup and view all the answers

    Which lipoprotein is involved in the transfer of cholesterol esters?

    <p>IDL</p> Signup and view all the answers

    Which lipoprotein is synthesized by several mechanisms and contains apoA1, CII, and E?

    <p>HDL</p> Signup and view all the answers

    Which lipoprotein is associated with an autosomal dominant disorder of the apoB gene when the missense mutation interferes with its recognition by the LDL receptor?

    <p>LDL</p> Signup and view all the answers

    Which lipoprotein is responsible for transporting dietary triglycerides from the intestine to peripheral tissues?

    <p>Chylomicrons</p> Signup and view all the answers

    Which lipoprotein is considered the 'bad cholesterol' because it carries cholesterol from the liver to peripheral tissues?

    <p>LDL</p> Signup and view all the answers

    Which lipoprotein is considered the 'good cholesterol' because it carries cholesterol from peripheral tissues back to the liver for excretion?

    <p>HDL</p> Signup and view all the answers

    Which lipoprotein is synthesized in the liver and transports endogenous triglycerides and cholesterol to peripheral tissues?

    <p>VLDL</p> Signup and view all the answers

    Which lipoprotein is formed from the metabolism of VLDL and carries cholesterol to the liver?

    <p>IDL</p> Signup and view all the answers

    Which lipoprotein is the largest and least dense, and primarily carries triglycerides?

    <p>Chylomicrons</p> Signup and view all the answers

    Which lipoprotein is responsible for reverse cholesterol transport, carrying cholesterol from peripheral tissues back to the liver?

    <p>HDL</p> Signup and view all the answers

    Which apolipoprotein is the primary structural protein of HDL and plays a crucial role in reverse cholesterol transport?

    <p>ApoA-I</p> Signup and view all the answers

    Which essential enzyme is responsible for hydrolyzing triglycerides in lipoproteins, releasing free fatty acids for uptake by peripheral tissues?

    <p>Lipoprotein lipase</p> Signup and view all the answers

    Which essential enzyme is responsible for esterifying free cholesterol in HDL, promoting cholesterol efflux from peripheral tissues?

    <p>LCAT</p> Signup and view all the answers

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