Cholesterol Transport

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30 Questions

Which lipoprotein is responsible for delivering dietary lipids to the liver?

Chylomicrons

Which lipoprotein is the precursor of LDL?

VLDL

Which lipoprotein is associated with reverse cholesterol transport?

HDL

Which lipoprotein is the most dense and smallest?

LDL

Which lipoprotein is responsible for mediating synthesis and secretion of chylomicrons?

Apo B-48

Which lipoprotein has the highest content of cholesterol esters?

LDL

Which lipoprotein is associated with familial hypercholesterolemia?

LDL

Which lipoprotein is responsible for delivering endogenous lipids to peripheral tissues?

VLDL

Which lipoprotein is least dense and larger in size?

Chylomicrons

Which lipoprotein is required for HDL formation and activates LCAT?

Apo A-1

Which lipoprotein is involved in reverse cholesterol transport?

HDL

Which lipoprotein carries the most direct relationship to atherosclerosis?

LDL

Which lipoprotein is considered vasoprotective?

HDL

Which lipoprotein is primarily regulated by the relative levels of circulating TG-rich lipoproteins?

IDL

Which lipoprotein is involved in the formation of fatty streaks in atherosclerosis?

LDL

Which lipoprotein is associated with Tangier disease when deficient?

HDL

Which lipoprotein is activated by ApoA-I and produces the majority of CE in circulating lipoproteins?

HDL

Which lipoprotein is involved in the transfer of cholesterol esters?

IDL

Which lipoprotein is synthesized by several mechanisms and contains apoA1, CII, and E?

HDL

Which lipoprotein is associated with an autosomal dominant disorder of the apoB gene when the missense mutation interferes with its recognition by the LDL receptor?

LDL

Which lipoprotein is responsible for transporting dietary triglycerides from the intestine to peripheral tissues?

Chylomicrons

Which lipoprotein is considered the 'bad cholesterol' because it carries cholesterol from the liver to peripheral tissues?

LDL

Which lipoprotein is considered the 'good cholesterol' because it carries cholesterol from peripheral tissues back to the liver for excretion?

HDL

Which lipoprotein is synthesized in the liver and transports endogenous triglycerides and cholesterol to peripheral tissues?

VLDL

Which lipoprotein is formed from the metabolism of VLDL and carries cholesterol to the liver?

IDL

Which lipoprotein is the largest and least dense, and primarily carries triglycerides?

Chylomicrons

Which lipoprotein is responsible for reverse cholesterol transport, carrying cholesterol from peripheral tissues back to the liver?

HDL

Which apolipoprotein is the primary structural protein of HDL and plays a crucial role in reverse cholesterol transport?

ApoA-I

Which essential enzyme is responsible for hydrolyzing triglycerides in lipoproteins, releasing free fatty acids for uptake by peripheral tissues?

Lipoprotein lipase

Which essential enzyme is responsible for esterifying free cholesterol in HDL, promoting cholesterol efflux from peripheral tissues?

LCAT

Test your knowledge on cholesterol transport with this quiz! Learn about the different functions and metabolism of blood lipoproteins, including chylomicrons, VLDL, IDL, LDL, and HDL. Compare and contrast forward and reverse cholesterol transport, and understand the role of apolipoproteins in cholesterol transportation.

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