Reverse Cholesterol Transport (RCT) Process Quiz

Test your knowledge on the process of reverse cholesterol transport (RCT) where hydrophobic cholesteryl ester is sequestered in the core of HDL and carried to the liver. Understand the importance of selective cholesterol transfer from peripheral cells to HDL and from HDL to the liver for bile acid synthesis and cholesterol homeostasis.

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@SportyBlessing

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Questions and Answers

What is the primary function of LDL particles?

To provide cholesterol to the peripheral tissues

Which apolipoprotein is found in LDL particles?

Apo-B100

What happens when cells with active LDL pathway release cholesterol?

It inhibits the de novo synthesis of cholesterol

How are high LDL levels clinically associated with atherosclerosis?

By causing hardening and narrowing of arteries Signup and view all the answers

Which factor can cause high LDL levels?

Obesity Signup and view all the answers

How is the uptake of additional cholesterol from plasma LDL regulated in cells?

By subjecting LDL receptors to feedback regulation Signup and view all the answers

Which apolipoprotein is required for the receptor-mediated endocytosis of chylomicron remnants?

Apo E Signup and view all the answers

What is the primary composition of HDL particles?

Primarily proteins (apoproteins) Signup and view all the answers

Which enzyme esterifies cholesterol taken up by HDL particles?

Lecithin:cholesterol acyltransferase (LCAT) Signup and view all the answers

Which lipoprotein is an activator of lipoprotein lipase (LPL)?

HDL Signup and view all the answers

What is the main function of HDL particles in cholesterol metabolism?

Take up cholesterol from peripheral tissues and return it to the liver Signup and view all the answers

Which apolipoprotein is synthesized and secreted by the liver and activates LCAT?

Apo A Signup and view all the answers

What is the main function of HDL particles in the reverse cholesterol transport process?

Transporting cholesterol from peripheral cells to the liver Signup and view all the answers

Which of the following components is NOT found in non-HDL cholesterol?

HDL cholesterol Signup and view all the answers

What is the significance of a high LDL/HDL ratio in relation to atherosclerosis?

A higher ratio indicates increased risk of atherosclerosis Signup and view all the answers

What role do LDL particles play in regulating cholesterol content within cells?

Delivering cholesterol to peripheral cells from the liver Signup and view all the answers

Which apolipoprotein primarily constitutes the structure of LDL particles?

ApoB-100 Signup and view all the answers

How does the reverse cholesterol transport process affect plasma HDL concentration in relation to atherosclerosis?

Higher HDL concentration is associated with reduced risk of atherosclerosis Signup and view all the answers

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