Reverse Cholesterol Transport (RCT) Process Quiz

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Questions and Answers

What is the primary function of LDL particles?

  • To transport triglycerides throughout the body
  • To form a protective layer around arteries
  • To provide cholesterol to the peripheral tissues (correct)
  • To regulate the synthesis of HMG CoA reductase

Which apolipoprotein is found in LDL particles?

  • Apo-C
  • Apo-E
  • Apo-B100 (correct)
  • Apo-B48

What happens when cells with active LDL pathway release cholesterol?

  • It enhances the uptake of cholesterol from plasma LDL
  • It stimulates the formation of HMG CoA reductase
  • It inhibits the de novo synthesis of cholesterol (correct)
  • It reduces the concentration of LDL receptors

How are high LDL levels clinically associated with atherosclerosis?

<p>By causing hardening and narrowing of arteries (D)</p> Signup and view all the answers

Which factor can cause high LDL levels?

<p>Obesity (A)</p> Signup and view all the answers

How is the uptake of additional cholesterol from plasma LDL regulated in cells?

<p>By subjecting LDL receptors to feedback regulation (C)</p> Signup and view all the answers

Which apolipoprotein is required for the receptor-mediated endocytosis of chylomicron remnants?

<p>Apo E (C)</p> Signup and view all the answers

What is the primary composition of HDL particles?

<p>Primarily proteins (apoproteins) (D)</p> Signup and view all the answers

Which enzyme esterifies cholesterol taken up by HDL particles?

<p>Lecithin:cholesterol acyltransferase (LCAT) (C)</p> Signup and view all the answers

Which lipoprotein is an activator of lipoprotein lipase (LPL)?

<p>HDL (C)</p> Signup and view all the answers

What is the main function of HDL particles in cholesterol metabolism?

<p>Take up cholesterol from peripheral tissues and return it to the liver (C)</p> Signup and view all the answers

Which apolipoprotein is synthesized and secreted by the liver and activates LCAT?

<p>Apo A (C)</p> Signup and view all the answers

What is the main function of HDL particles in the reverse cholesterol transport process?

<p>Transporting cholesterol from peripheral cells to the liver (C)</p> Signup and view all the answers

Which of the following components is NOT found in non-HDL cholesterol?

<p>HDL cholesterol (D)</p> Signup and view all the answers

What is the significance of a high LDL/HDL ratio in relation to atherosclerosis?

<p>A higher ratio indicates increased risk of atherosclerosis (A)</p> Signup and view all the answers

What role do LDL particles play in regulating cholesterol content within cells?

<p>Delivering cholesterol to peripheral cells from the liver (A)</p> Signup and view all the answers

Which apolipoprotein primarily constitutes the structure of LDL particles?

<p>ApoB-100 (D)</p> Signup and view all the answers

How does the reverse cholesterol transport process affect plasma HDL concentration in relation to atherosclerosis?

<p>Higher HDL concentration is associated with reduced risk of atherosclerosis (D)</p> Signup and view all the answers

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