Cholelithiasis and Cholecystitis Overview
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Questions and Answers

What is the most common composition of gallstones in cholelithiasis?

  • Bilirubin
  • Uric acid
  • Calcium oxalate
  • Cholesterol (correct)
  • Which symptom is typically associated with uncomplicated cholelithiasis?

  • Postprandial biliary colic (correct)
  • Jaundice
  • Fever with chills
  • Constant right upper quadrant pain
  • What are the risk factors most closely associated with cholelithiasis?

  • High protein intake and male gender
  • Male gender, smoking, and vegetarian diet
  • Male gender, diabetes, and chronic alcohol use
  • Female gender, obesity, and rapid weight loss (correct)
  • The '4 Fs' associated with cholelithiasis refer to which of the following?

    <p>Forty, female, fatty, fertile</p> Signup and view all the answers

    Which diagnostic test is primarily used to confirm gallstones in cholelithiasis?

    <p>Abdominal ultrasound</p> Signup and view all the answers

    What is the primary cause of acute cholecystitis?

    <p>Gallstone obstruction of the cystic duct</p> Signup and view all the answers

    A positive Murphy's sign is indicative of which condition?

    <p>Acute cholecystitis</p> Signup and view all the answers

    Chronic cholecystitis is most often associated with which of the following?

    <p>Recurrent episodes of acute cholecystitis</p> Signup and view all the answers

    Acalculous cholecystitis is most commonly found in which group of patients?

    <p>Critically ill patients.</p> Signup and view all the answers

    What is the primary treatment option for acute cholecystitis?

    <p>Cholecystectomy</p> Signup and view all the answers

    Which symptom typically indicates acalculous cholecystitis?

    <p>RUQ pain in critically ill patients</p> Signup and view all the answers

    How can acute cholecystitis be differentiated from chronic cholecystitis?

    <p>By the duration and severity of inflammation</p> Signup and view all the answers

    Which antibiotic regimen is suitable for treating acute cholecystitis?

    <p>Ceftriaxone and metronidazole</p> Signup and view all the answers

    What primary sign indicates choledocholithiasis?

    <p>Persistent jaundice and elevated liver enzymes</p> Signup and view all the answers

    Which imaging technique is the most accurate for diagnosing choledocholithiasis?

    <p>MRCP</p> Signup and view all the answers

    Charcot's triad for cholangitis includes which signs?

    <p>Fever, RUQ pain, jaundice</p> Signup and view all the answers

    What additional symptoms are included in Reynolds' pentad for severe cholangitis?

    <p>Hypotension and altered mental status.</p> Signup and view all the answers

    What is the best first-line treatment for ascending cholangitis?

    <p>Broad-spectrum antibiotics and biliary drainage</p> Signup and view all the answers

    What is the most common cause of acute pancreatitis in the United States?

    <p>Gallstones</p> Signup and view all the answers

    Which laboratory test is considered the most specific for diagnosing acute pancreatitis?

    <p>Lipase</p> Signup and view all the answers

    Which imaging method is most commonly used to diagnose acute pancreatitis?

    <p>CT scan</p> Signup and view all the answers

    Which enzyme's elevation is NOT part of Ranson's criteria for assessing acute pancreatitis severity?

    <p>Elevated ALT &gt;150 U/L</p> Signup and view all the answers

    Which of the following is a potential complication of untreated cholelithiasis that involves an inflammatory condition of the pancreas?

    <p>Pancreatitis</p> Signup and view all the answers

    What characteristic symptom commonly occurs after meals in patients with uncomplicated cholelithiasis?

    <p>Postprandial biliary colic</p> Signup and view all the answers

    Which demographic trait is most often associated with an increased risk for developing cholelithiasis?

    <p>Female gender</p> Signup and view all the answers

    During the diagnosis of acute cholecystitis, which imaging study is most sensitive in detecting cystic duct occlusion?

    <p>HIDA scan</p> Signup and view all the answers

    What laboratory finding would likely be most indicative of an acute inflammatory process in cholecystitis?

    <p>Elevated white blood cell count</p> Signup and view all the answers

    Which of the following conditions is characterized by recurrent inflammation and gallbladder damage potentially leading to chronic complications?

    <p>Chronic cholecystitis</p> Signup and view all the answers

    What term describes the collection of risk factors often remembered as the '4 Fs' relevant to gallstone formation?

    <p>Forty, female, fatty, fertile</p> Signup and view all the answers

    Which symptom would NOT typically indicate acute cholecystitis?

    <p>Severe jaundice</p> Signup and view all the answers

    What is typically the initial symptom that leads patients to seek treatment for gallstones?

    <p>Postprandial pain</p> Signup and view all the answers

    In which condition would you expect a significant elevation of alkaline phosphatase levels?

    <p>Acute cholangitis</p> Signup and view all the answers

    What differentiates acute pancreatitis from chronic pancreatitis based on its onset and symptoms?

    <p>Duration and severity of inflammation</p> Signup and view all the answers

    Which symptom is most indicative of cholangitis, considering the potential severity of the condition?

    <p>Hypotension and altered mental status</p> Signup and view all the answers

    What first-line treatment is generally indicated for patients diagnosed with acute cholecystitis?

    <p>Cholecystectomy</p> Signup and view all the answers

    Which finding is considered a hallmark indicator of chronic pancreatitis upon imaging studies?

    <p>Calcifications in the pancreas</p> Signup and view all the answers

    In terms of symptoms, which of the following is a critical clinical manifestation of choledocholithiasis?

    <p>Persistent jaundice and elevated liver enzymes</p> Signup and view all the answers

    What is considered a common long-term complication associated with chronic pancreatitis?

    <p>Diabetes mellitus</p> Signup and view all the answers

    Which of the following is the most accurate imaging technique for diagnosing choledocholithiasis?

    <p>MRCP</p> Signup and view all the answers

    Which class of antibiotics is recommended as part of the treatment regimen for acute cholecystitis?

    <p>Ceftriaxone and metronidazole</p> Signup and view all the answers

    What is the significant risk factor associated with the development of cholangiocarcinoma?

    <p>Primary sclerosing cholangitis</p> Signup and view all the answers

    What initial approach is recommended for managing ascending cholangitis?

    <p>Biliary drainage and broad-spectrum antibiotics</p> Signup and view all the answers

    Study Notes

    Cholelithiasis

    • Most common composition: Cholesterol.
    • Hallmark symptom: Postprandial biliary colic (pain after eating).
    • Risk factors: Female gender, obesity, rapid weight loss.
    • "4 Fs": Forty, female, fatty, fertile.
    • Diagnosis: Abdominal ultrasound.
    • Complications: Pancreatitis.

    Cholecystitis (Acute, Chronic, and Acalculous)

    • Acute cause: Gallstone obstruction of the cystic duct.
    • Murphy's sign: Positive in acute cholecystitis (pain with palpation of the gallbladder).
    • Lab abnormality: Elevated white blood cell count.
    • Diagnosis: HIDA scan (most sensitive).
    • Chronic cholecystitis: Recurrent acute episodes.
    • Acalculous cholecystitis: In critically ill patients.
    • Treatment: Cholecystectomy (surgical removal).
    • Clinical feature of acalculous: RUQ pain in critically ill patients.
    • Difference from chronic: Duration and severity of inflammation.
    • Antibiotic regimen: Ceftriaxone and metronidazole

    Choledocholithiasis and Cholangitis

    • Choledocholithiasis hallmark: Persistent jaundice and elevated liver enzymes.
    • Diagnosis: MRCP (most accurate).
    • Charcot's triad: Fever, RUQ pain, and jaundice.
    • Reynold's pentad: Charcot's triad plus hypotension and altered mental status.
    • Treatment: Broad-spectrum antibiotics and biliary drainage.

    Pancreatitis (Acute and Chronic)

    • Most common cause (US): Gallstones.
    • Specific lab test: Lipase.
    • Imaging modality: CT scan.
    • Ranson's criteria: Factors to assess severity (e.g., age, white blood cell count, serum calcium).
    • Chronic cause: Alcohol abuse.
    • Chronic complication: Diabetes mellitus.
    • Chronic clinical feature: Epigastric pain radiating to the back.
    • Dietary modification: Low-fat diet.
    • Radiographic finding: Calcifications in the pancreas.
    • Enzyme supplementation: Pancreatic enzyme replacement therapy (PERT).
    • Pseudocyst association: Acute pancreatitis.

    Biliary and Pancreatic Cancer

    • Cholangiocarcinoma risk factor: Primary sclerosing cholangitis.
    • Pancreatic cancer tumor marker: CA 19-9.
    • Painless jaundice: Suggestive of pancreatic cancer.
    • Diagnosis (Pancreatic cancer): Endoscopic ultrasound (EUS).
    • Cholangiocarcinoma presentation: Jaundice, pruritus, weight loss.
    • Treatment (pancreatic cancer): Whipple procedure.
    • Biliary cancer association: Primary sclerosing cholangitis.
    • Advanced pancreatic cancer feature: Jaundice, weight loss, and back pain.

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    Description

    Test your knowledge on cholelithiasis and cholecystitis, including their symptoms, risk factors, and complications. This quiz covers key concepts like the 4 Fs of gallstones, diagnostic methods, and treatment options for acute and chronic cholecystitis. Enhance your understanding of these common gallbladder disorders.

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