10 Questions
What happens at low substrate concentrations in allosteric enzymes?
There is little enzyme activity
How does cooperativity affect enzyme activity in allosteric enzymes?
It leads to a sharp increase in reaction velocity in the middle of the curve
How do positive effectors modulate allosteric enzymes?
They lower the threshold concentration level of substrate needed for activity
What are heterotropic effects on allosteric enzymes?
Shift the curve to the left if inhibitors
How does the Sequential Model account for allosteric effects?
Each site of the enzyme changes as soon as one substrate binds
What is the effect of negative effectors on allosteric enzymes?
They raise the threshold concentration level of substrate needed for activity
What distinguishes allosteric enzymes from Michaelis-Menten enzymes with respect to sensitivity to substrate concentration?
Allosteric enzymes require less change in substrate concentration for a given change in velocity near KM
How do homotropic effects differ from heterotropic effects on allosteric enzymes?
Homotropic effects involve effects of regulatory molecules on allosteric enzymes
What characterizes enzyme behavior according to the text?
Most enzymes exhibit a combination of sequential and concerted models
What is a characteristic of an R form in allosteric enzymes?
It stabilizes active sites in a way that makes substrate binding easier
Explore concepts related to chemical reaction rates and kinetics, including enzyme-catalyzed reactions, velocity of a reaction, and rate constants. Learn about first-order reactions and the relationship between reaction velocity and reactant concentration.
Make Your Own Quizzes and Flashcards
Convert your notes into interactive study material.
Get started for free
