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Questions and Answers
Which type of cells lack a true nucleus and membrane-bound organelles?
Which type of cells lack a true nucleus and membrane-bound organelles?
- Mitochondrial cells
- RNA cells
- Eukaryotic cells
- Prokaryotic cells (correct)
What are the basic building blocks of proteins?
What are the basic building blocks of proteins?
- Amino acids (correct)
- Fatty acids
- Nucleotides
- Monosaccharides
Which molecule is known as the energy currency of the cell?
Which molecule is known as the energy currency of the cell?
- ATP (correct)
- DNA
- Glucose
- RNA
What are the functional groups that show characteristic physical and chemical properties in biomolecules?
What are the functional groups that show characteristic physical and chemical properties in biomolecules?
In the context of biomolecules, what does the term 'polymer' refer to?
In the context of biomolecules, what does the term 'polymer' refer to?
What is the significance of Friedrich Wöhler's experiment in 1828 concerning organic chemistry?
What is the significance of Friedrich Wöhler's experiment in 1828 concerning organic chemistry?
Which types of cells contain membrane-bound organelles and a true nucleus?
Which types of cells contain membrane-bound organelles and a true nucleus?
What role do proteins and nucleic acids play in life processes?
What role do proteins and nucleic acids play in life processes?
'ATP' is considered as the energy currency of the cell because it:
'ATP' is considered as the energy currency of the cell because it:
What is the relationship between the nucleotide sequence in nucleic acids and the amino acid sequence in proteins?
What is the relationship between the nucleotide sequence in nucleic acids and the amino acid sequence in proteins?
What was the significance of the discovery of ribozymes?
What was the significance of the discovery of ribozymes?
What is the main difference between prokaryotes and eukaryotes?
What is the main difference between prokaryotes and eukaryotes?
Which statement best describes the catalytic properties of RNA according to the text?
Which statement best describes the catalytic properties of RNA according to the text?
What is the meaning of 'prokaryote' based on its Greek derivation?
What is the meaning of 'prokaryote' based on its Greek derivation?
Why do prokaryotes not possess membrane-bound organelles like eukaryotes?
Why do prokaryotes not possess membrane-bound organelles like eukaryotes?
What function do ribozymes perform?
What function do ribozymes perform?
What role did Thomas R. Cech and Sidney Altman play in RNA research?
What role did Thomas R. Cech and Sidney Altman play in RNA research?
'Eukaryote' originates from the Greek words meaning:
'Eukaryote' originates from the Greek words meaning:
Which type of cells have a well-defined nucleus surrounded by a nuclear membrane?
Which type of cells have a well-defined nucleus surrounded by a nuclear membrane?
What is the ultimate source of energy for all life on earth?
What is the ultimate source of energy for all life on earth?
In biochemical energetics, what happens if ΔG is greater than 0?
In biochemical energetics, what happens if ΔG is greater than 0?
What type of reactions are favored: Exothermic/Exergonic or Endothermic/Endergonic?
What type of reactions are favored: Exothermic/Exergonic or Endothermic/Endergonic?
Which type of organisms use light energy to drive the synthesis of carbohydrates?
Which type of organisms use light energy to drive the synthesis of carbohydrates?
In terms of energetics, what does a negative ΔG indicate?
In terms of energetics, what does a negative ΔG indicate?
In biological macromolecules, what is the 'sense' or directionality that they possess?
In biological macromolecules, what is the 'sense' or directionality that they possess?
What is the correct statement regarding the linkages in polysaccharides starch and cellulose?
What is the correct statement regarding the linkages in polysaccharides starch and cellulose?
What type of bond is formed between the 3'-OH of ribose ring of one nucleotide and the 5'-OH of ribose ring of a neighboring nucleotide in nucleic acids?
What type of bond is formed between the 3'-OH of ribose ring of one nucleotide and the 5'-OH of ribose ring of a neighboring nucleotide in nucleic acids?
Which of the following statements about enzymes is true?
Which of the following statements about enzymes is true?
What occurs when the 5' group of a nucleotide triphosphate interacts with the free 3' hydroxyl group of a nucleotide chain?
What occurs when the 5' group of a nucleotide triphosphate interacts with the free 3' hydroxyl group of a nucleotide chain?
Which type of linkage is observed in the polysaccharide starch?
Which type of linkage is observed in the polysaccharide starch?
What is the correct order of amino acids in the sequence Ser-Val-Tyr-Cys?
What is the correct order of amino acids in the sequence Ser-Val-Tyr-Cys?
What happens when the bond between the first phosphorus atom and the oxygen atom linking it to the next phosphate group breaks?
What happens when the bond between the first phosphorus atom and the oxygen atom linking it to the next phosphate group breaks?
What is the significance of the sense of directionality in biological macromolecules?
What is the significance of the sense of directionality in biological macromolecules?
Which type of linkages are observed in both starch and cellulose?
Which type of linkages are observed in both starch and cellulose?
What happens when the 3' hydroxyl group of one nucleotide forms a bond with the 5' oxygen atom of another nucleotide in a nucleic acid chain?
What happens when the 3' hydroxyl group of one nucleotide forms a bond with the 5' oxygen atom of another nucleotide in a nucleic acid chain?
What is the role of enzymes that display catalytic activity according to the text?
What is the role of enzymes that display catalytic activity according to the text?
In nucleic acids, which ribose ring atom forms a bond with the 5'-OH of a neighboring nucleotide's ribose ring?
In nucleic acids, which ribose ring atom forms a bond with the 5'-OH of a neighboring nucleotide's ribose ring?
What characteristic distinguishes Ser-Val-Tyr-Cys from Cys-Tyr-Val-Ser?
What characteristic distinguishes Ser-Val-Tyr-Cys from Cys-Tyr-Val-Ser?
What is the significance of the directionality possessed by biological macromolecules?
What is the significance of the directionality possessed by biological macromolecules?
Which statement best describes the linkages in starch and cellulose as mentioned in the text?
Which statement best describes the linkages in starch and cellulose as mentioned in the text?
'ATP' is considered the energy currency of the cell primarily because it:
'ATP' is considered the energy currency of the cell primarily because it:
What type of linkage is observed in the polysaccharide cellulose?
What type of linkage is observed in the polysaccharide cellulose?
What is the significance of the directionality in biological macromolecules?
What is the significance of the directionality in biological macromolecules?
Which nucleotide is complementary to adenine in a DNA molecule?
Which nucleotide is complementary to adenine in a DNA molecule?
Enzymes increase the rate of a reaction by:
Enzymes increase the rate of a reaction by:
What is the role of tRNA in protein synthesis?
What is the role of tRNA in protein synthesis?
What does the genetic code dictate in protein synthesis?
What does the genetic code dictate in protein synthesis?
How do enzymes achieve specificity in catalyzing reactions?
How do enzymes achieve specificity in catalyzing reactions?
What is the significance of phosphodiester linkages in nucleic acids?
What is the significance of phosphodiester linkages in nucleic acids?
What is the main difference in the linkages observed in the polysaccharides starch and cellulose?
What is the main difference in the linkages observed in the polysaccharides starch and cellulose?
In terms of biological macromolecules, what does the 'sense' of directionality mean?
In terms of biological macromolecules, what does the 'sense' of directionality mean?
Which statement best describes the relationship between the genetic code and the amino acid sequence?
Which statement best describes the relationship between the genetic code and the amino acid sequence?
What is a key characteristic of enzymes related to their catalytic activity?
What is a key characteristic of enzymes related to their catalytic activity?
What is the primary role of nucleic acids in relation to the amino acid sequence of proteins?
What is the primary role of nucleic acids in relation to the amino acid sequence of proteins?
Why is it significant that RNA has been considered the original coding material by many scientists?
Why is it significant that RNA has been considered the original coding material by many scientists?
What contributes significantly to the catalytic effectiveness of an enzyme?
What contributes significantly to the catalytic effectiveness of an enzyme?
Why do certain types of RNA like ribozymes have gained recognition for their catalytic activity?
Why do certain types of RNA like ribozymes have gained recognition for their catalytic activity?
What did Thomas R. Cech and Sidney Altman receive the Nobel Prize in Chemistry for in 1989?
What did Thomas R. Cech and Sidney Altman receive the Nobel Prize in Chemistry for in 1989?
What type of linkage is observed in the polysaccharide cellulose?
What type of linkage is observed in the polysaccharide cellulose?
In biological macromolecules, what does the term 'directionality' refer to?
In biological macromolecules, what does the term 'directionality' refer to?
How is the genetic code related to the amino acid sequence in proteins?
How is the genetic code related to the amino acid sequence in proteins?
What do enzymes primarily do in biochemical reactions?
What do enzymes primarily do in biochemical reactions?
Which of the following statements best describes the catalytic properties of ribozymes?
Which of the following statements best describes the catalytic properties of ribozymes?
The bond between the 3'-OH group of one nucleotide and the 5'-phosphate group of the next nucleotide in DNA molecules is known as:
The bond between the 3'-OH group of one nucleotide and the 5'-phosphate group of the next nucleotide in DNA molecules is known as:
What is the significance of the arrangement of functional groups in biological macromolecules?
What is the significance of the arrangement of functional groups in biological macromolecules?
Study Notes
Biomolecules and Biochemistry
- Biomolecules are molecules produced in living organisms, and their reactions can be described by the methods of organic chemistry.
- The experiment of Friedrich Wöhler in 1828 demonstrated the possibility of synthesizing organic compounds from inorganic substances.
Functional Groups
- A functional group is an atom or group of atoms that show characteristic physical and chemical properties.
- Examples of functional groups include phosphoester and phosphoanhydride in ATP, which is considered the energy currency of the cell.
Origins of Life
- The "big bang" theory proposes that all matter was originally confined in a very small space, which expanded with great force, and has been decreasing in temperature ever since.
- In the earliest stages of the universe, only H, He, and Li were present, with other elements formed by thermonuclear reactions in stars.
- Gases present in the early earth's atmosphere included NH3, H2S, CO, CO2, CH4, N2, H2, and H2O, from which biomolecules could have arisen under abiotic conditions.
Directionality in Macromolecules
- Biological macromolecules and their building blocks have a "sense" or directionality, with a clear N-terminus and C-terminus.
- Examples of directional macromolecules include proteins, polysaccharides, and nucleic acids.
Enzymes and Catalytic Activity
- Enzymes are a class of proteins (and RNA) that display catalytic activity, with the catalytic effectiveness depending on their amino acid sequence.
- Some types of RNA have catalytic activity (ribozymes), capable of catalyzing their own further processing.
- The discovery of catalytic properties of RNA earned Thomas R. Cech and Sidney Altman the Nobel Prize in chemistry in 1989.
Prokaryotes and Eukaryotes
- Prokaryotes are single-celled organisms, lacking a well-defined nucleus, including bacteria and archae.
- Eukaryotes are organisms with a true nucleus, surrounded by a nuclear membrane, and can be single-celled or multicellular.
Biochemical Energetics
- All cells require energy to function, with light from the sun being the ultimate source of energy for all life on earth.
- The energetics of a chemical reaction depends on the free energy change (ΔG), with spontaneous reactions having ΔG < 0 and non-spontaneous reactions having ΔG > 0.
- Exergonic reactions are favored, while endergonic reactions are not favored, unless energy is supplied from an external source.
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Description
This quiz covers the fundamental concepts of biochemistry including functional groups, biomolecules, macromolecules, origins of life, prokaryotes vs. eukaryotes, kingdoms and domains, biochemical energetics, levels of structural organization in the human body, and the chemical foundations of biochemistry. It also includes an overview of organic chemistry and its relevance to biochemistry.