Central Dogma of Molecular Biology: Replication Process

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What is the function of DNA ligase in DNA replication?

Joining Okazaki fragments on the lagging strand

Which enzyme is responsible for replacing primers during DNA replication?

DNA polymerase I

What can happen if DNA replication errors are not patched up, especially at fragile sites?

Breaks in DNA leading to potential cancer

In which direction does transcription occur?

<p>5' to 3'</p> Signup and view all the answers

Which molecule is responsible for carrying amino acids during protein synthesis?

<p>tRNA</p> Signup and view all the answers

What is the purpose of adding a 5'-GTP cap and poly-A tail to mature mRNA?

<p>Provide chemical protection to mRNA</p> Signup and view all the answers

Which phase/step of the cell cycle is replication a prerequisite for?

<p>S phase</p> Signup and view all the answers

What is the main function of Topoisomerase during DNA replication?

<p>Stretches/uncoils DNA to ensure it is straight for unzipping</p> Signup and view all the answers

Which enzyme synthesizes new DNA strands in the 5' to 3' direction during elongation?

<p>DNA polymerase III</p> Signup and view all the answers

Where does replication initiation begin in the DNA molecule?

<p>At the origin or replication centre</p> Signup and view all the answers

What is the direction of synthesis in the leading strand during DNA replication?

<p>5' to 3'</p> Signup and view all the answers

What is the main function of Single-stranded DNA binding proteins during replication?

<p>Stabilizes DNA to prevent breakdown during unzipping</p> Signup and view all the answers

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