Cellular Pathology Concepts

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Questions and Answers

Which of the following cellular adaptations is characterized by an increase in cell size due to increased workload?

Hypertrophy (correct)
Metaplasia
Hyperplasia
Atrophy

In the context of cell injury, what is the primary mechanism by which ischemia leads to ATP depletion?

Increased mitochondrial oxidative phosphorylation
Reduced oxygen supply to the electron transport chain (correct)
Increased influx of calcium ions
Activation of caspases

Which type of necrosis is most commonly associated with tuberculosis infections?

Liquefactive necrosis
Coagulative necrosis
Caseous necrosis (correct)
Fat necrosis

What is the fundamental difference between apoptosis and necrosis regarding inflammation?

Necrosis is always associated with inflammation, while apoptosis typically does not induce inflammation. (B) Signup and view all the answers

Which of the following best describes the role of macrophages in chronic inflammation?

Phagocytosis, cytokine production, and antigen presentation. (B) Signup and view all the answers

Which of the following is NOT a typical cause of granulomatous inflammation?

Acute viral infections (C) Signup and view all the answers

What is the primary difference between regeneration and scar formation in tissue repair?

Regeneration replaces damaged cells with cells of the same type, while scar formation replaces damaged tissue with fibrous tissue. (C) Signup and view all the answers

What is the role of formalin in histopathology?

To preserve tissue structure by fixation. (A) Signup and view all the answers

In histopathology, what tissue component is stained blue by Masson's trichrome stain?

Collagen (D) Signup and view all the answers

Which histopathological technique uses antibodies to detect specific proteins in tissue samples?

Immunohistochemistry (IHC) (A) Signup and view all the answers

Flashcards

Pathology

The study of disease, including its causes, mechanisms, progression, and effects.

Etiology

The cause of a disease; can be genetic, environmental, or multifactorial.