Cell Junctions: Tight Junctions Quiz
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Questions and Answers

What is the main function of hemidesmosomes?

  • Connect cells to each other
  • Facilitate communication between neighboring cells
  • Anchor cells to the basement membrane (correct)
  • Synthesize proteins for cell adhesion
  • How many connexin protein molecules form a hemichannel in the structure of gap junctions?

  • 6 (correct)
  • 4
  • 8
  • 10
  • What transmembrane glycoproteins are present in hemidesmosomes?

  • Collagens
  • Laminins
  • Connexins
  • Integrins (correct)
  • Which type of junction is responsible for connecting epithelial cells to each other?

    <p>Desmosomes</p> Signup and view all the answers

    What is the primary function of the basement membrane?

    <p>Connect epithelial tissue to connective tissue</p> Signup and view all the answers

    Which structure contains collagen produced by fibroblasts in close proximity to connective tissue?

    <p>Lamina reticularis</p> Signup and view all the answers

    'Connecting neighboring cells' is a function associated with:

    <p>Gap junctions</p> Signup and view all the answers

    'Anchoring cells to the basement membrane' is a role carried out by:

    <p>Desmosomes</p> Signup and view all the answers

    What is the main function of tight junctions?

    <p>Blocking intercellular movement of small solutes</p> Signup and view all the answers

    Which proteins are mainly responsible for forming tight junctions?

    <p>Occludins and claudins</p> Signup and view all the answers

    Where are tight junctions predominantly found in the body?

    <p>Stomach, intestine, and bladder</p> Signup and view all the answers

    What is the main function of adherens junctions?

    <p>Preventing cell separation during contraction</p> Signup and view all the answers

    Which type of junction keeps cell polarity by preventing migration of proteins between apical and basal surfaces?

    <p>Tight junctions</p> Signup and view all the answers

    What does the presence of adhesion plaques indicate?

    <p>Absence of tight junctions</p> Signup and view all the answers

    Which type of junction is located more towards the basal surface of epithelium cells?

    <p>Adherens junctions</p> Signup and view all the answers

    What is the role of desmosomes in cell-cell adhesion?

    <p>Preventing cell separation under mechanical stress</p> Signup and view all the answers

    What are the cell junctions that hold epithelial cells together?

    <p>Desmosomes</p> Signup and view all the answers

    Which type of cell junction is responsible for providing communication channels between adjacent cells?

    <p>Gap junctions</p> Signup and view all the answers

    Which cell junction provides mechanical strength and connects epithelial cells to the basement membrane?

    <p>Hemidesmosomes</p> Signup and view all the answers

    Which type of cell junction is involved in the selective passage of molecules through epithelial layers?

    <p>Tight junctions</p> Signup and view all the answers

    Which cell junction is essential for cell-cell adhesion and regulation of cell shape and movement?

    <p>Adherens junctions</p> Signup and view all the answers

    Which type of cell junction serves as a physical barrier to prevent leakage in between epithelial cells?

    <p>Zonula occludens</p> Signup and view all the answers

    Which type of cell junction aids in quick communication between cells by allowing fast passage of small molecules?

    <p>Connexin gap junctions</p> Signup and view all the answers

    Which cell junction plays a role in attaching actin filaments to the cell membrane and is important for tissue integrity?

    <p>Actin-binding junctions</p> Signup and view all the answers

    What type of junction connects the cytoskeleton of neighboring cells, providing strong adhesion between them?

    <p>Desmosomes</p> Signup and view all the answers

    Which junction forms a seal around the cell to prevent molecules from passing between cells?

    <p>Tight junctions</p> Signup and view all the answers

    What type of junction allows for the direct passage of ions and small molecules from one cell to another?

    <p>Gap junctions</p> Signup and view all the answers

    Which junction anchors epithelial cells to the basement membrane?

    <p>Hemidesmosomes</p> Signup and view all the answers

    What type of junction is responsible for connecting actin filaments between adjacent cells?

    <p>Adherens junctions</p> Signup and view all the answers

    When considering cell-cell communication, which junction is involved in signaling pathways between cells?

    <p>Gap junctions</p> Signup and view all the answers

    Which type of junction consists of cadherin proteins binding adjacent cells together?

    <p>Adherens junctions</p> Signup and view all the answers

    In terms of structural support, which type of junction provides a spot weld-like connection between cells?

    <p>Desmosomes</p> Signup and view all the answers

    What proteins are involved in the adherens junction?

    <p>Cadherins and catenins</p> Signup and view all the answers

    What is responsible for locking cadherin to the microfilament in the cell cytoplasm in an adherens junction?

    <p>Catenins</p> Signup and view all the answers

    Where are desmosomes typically found?

    <p>In the lateral wall of epithelial and cardiac tissue</p> Signup and view all the answers

    What do gap junctions allow to pass through them?

    <p>1 kDa molecules</p> Signup and view all the answers

    Which protein spans the gap between cell walls and binds to desmoplakin in a desmosome junction?

    <p>Cadherin</p> Signup and view all the answers

    What is the main function of tight junctions?

    <p>To provide structural integrity to cells</p> Signup and view all the answers

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