8 Questions
Cell injury can be reversible or irreversible.
True
Hypoxia is a type of toxin.
False
Infections can cause cell injury.
True
Physical injury always leads to cell death.
False
Oxidative stress is a type of cellular response to injury.
True
Mitochondrial dysfunction is a type of cellular change that occurs as a result of cell injury.
True
Tissue damage is a consequence of cell injury.
True
Genetic defects can cause cell injury.
True
Study Notes
Cell Injury
Definition
- Cell injury: reversible or irreversible harm to cells due to various insults, leading to cellular dysfunction or death.
Causes of Cell Injury
- Hypoxia: inadequate oxygen supply
- Infections: bacterial, viral, fungal, or parasitic infections
- Toxins: chemicals, drugs, or environmental pollutants
- Physical injury: mechanical trauma, radiation, or temperature extremes
- Nutritional deficiencies: lack of essential nutrients
- Genetic defects: inherited or acquired genetic mutations
Cellular Responses to Injury
- Inflammation: activation of immune response, swelling, and repair
- Oxidative stress: imbalance between reactive oxygen species (ROS) and antioxidants
- Apoptosis: programmed cell death
- Necrosis: unprogrammed cell death
Cellular Changes
- Cell swelling: increased water and ion uptake
- Mitochondrial dysfunction: impaired energy production
- Lysosomal rupture: leakage of digestive enzymes
- Cytoskeleton disruption: altered cellular structure and function
- DNA damage: genetic mutations and potential cancer development
Consequences of Cell Injury
- Tissue damage: organ dysfunction and disease
- Cancer: uncontrolled cell growth and tumor formation
- Cell death: loss of cellular function and tissue integrity
Test your knowledge of cell injury, including its definition, causes, cellular responses, changes, and consequences. Learn about the effects of hypoxia, infections, toxins, and more on cellular function and tissue health.
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