Cell Injury: Causes, Responses, and Consequences
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Questions and Answers

Cell injury can be reversible or irreversible.

True

Hypoxia is a type of toxin.

False

Infections can cause cell injury.

True

Physical injury always leads to cell death.

<p>False</p> Signup and view all the answers

Oxidative stress is a type of cellular response to injury.

<p>True</p> Signup and view all the answers

Mitochondrial dysfunction is a type of cellular change that occurs as a result of cell injury.

<p>True</p> Signup and view all the answers

Tissue damage is a consequence of cell injury.

<p>True</p> Signup and view all the answers

Genetic defects can cause cell injury.

<p>True</p> Signup and view all the answers

Study Notes

Cell Injury

Definition

  • Cell injury: reversible or irreversible harm to cells due to various insults, leading to cellular dysfunction or death.

Causes of Cell Injury

  • Hypoxia: inadequate oxygen supply
  • Infections: bacterial, viral, fungal, or parasitic infections
  • Toxins: chemicals, drugs, or environmental pollutants
  • Physical injury: mechanical trauma, radiation, or temperature extremes
  • Nutritional deficiencies: lack of essential nutrients
  • Genetic defects: inherited or acquired genetic mutations

Cellular Responses to Injury

  • Inflammation: activation of immune response, swelling, and repair
  • Oxidative stress: imbalance between reactive oxygen species (ROS) and antioxidants
  • Apoptosis: programmed cell death
  • Necrosis: unprogrammed cell death

Cellular Changes

  • Cell swelling: increased water and ion uptake
  • Mitochondrial dysfunction: impaired energy production
  • Lysosomal rupture: leakage of digestive enzymes
  • Cytoskeleton disruption: altered cellular structure and function
  • DNA damage: genetic mutations and potential cancer development

Consequences of Cell Injury

  • Tissue damage: organ dysfunction and disease
  • Cancer: uncontrolled cell growth and tumor formation
  • Cell death: loss of cellular function and tissue integrity

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Description

Test your knowledge of cell injury, including its definition, causes, cellular responses, changes, and consequences. Learn about the effects of hypoxia, infections, toxins, and more on cellular function and tissue health.

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