Cell Death and Disease
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Questions and Answers

What is a characteristic of necrosis?

  • Maintenance of plasma membrane integrity
  • Cell phagocytosed by macrophages
  • Shrinkage of the cell
  • Swelling of the cell (correct)
  • What happens in apoptosis?

  • Shrinkage of cell (correct)
  • Maintenance of plasma membrane integrity
  • Organelles are broken down and reused as nutrients
  • Does not always result in cell death
  • What can cause cells to die?

  • High oxygen levels
  • UV (correct)
  • Increased ATP production
  • Low glucose levels
  • What is a result of ischemia/reperfusion?

    <p>Death of surrounding cells</p> Signup and view all the answers

    What is a characteristic of autophagy?

    <p>Organelles are broken down and reused as nutrients</p> Signup and view all the answers

    Which process involves the release of cell contents into surrounding tissue?

    <p>Necrosis</p> Signup and view all the answers

    What is a characteristic of apoptosis?

    <p>Shrinkage of cell</p> Signup and view all the answers

    Which process involves the breakdown and reuse of organelles as nutrients?

    <p>Autophagy</p> Signup and view all the answers

    What is a result of ischemia/reperfusion?

    <p>Death of surrounding cells</p> Signup and view all the answers

    What signals the cell to die in response to factors like UV and cytotoxic T-cells?

    <p>Cell death signals</p> Signup and view all the answers

    How are signals transmitted to the nucleus for cell division?

    <p>Via signal transduction and mitogenic signalling pathways</p> Signup and view all the answers

    What maintains the balance in cell proliferation and inhibition in tissues?

    <p>External stimuli and normal tissue restoration</p> Signup and view all the answers

    What characterises receptor tyrosine kinases (RTKs) and their activation?

    <p>Cytoplasmic tyrosine kinase domain phosphorylates peptides when ligands bind</p> Signup and view all the answers

    What happens when a cell receives a mitogenic signal?

    <p>Activated protein translation and pathways for energy production, anabolic metabolism, and creation of organelles</p> Signup and view all the answers

    How does oncogenic activation of p21 RAS influence cell proliferation?

    <p>Stimulates excessive proliferation by amplifying signals</p> Signup and view all the answers

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