Cell Death and Disease
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Questions and Answers

What is a characteristic of necrosis?

  • Maintenance of plasma membrane integrity
  • Cell phagocytosed by macrophages
  • Shrinkage of the cell
  • Swelling of the cell (correct)

What happens in apoptosis?

  • Shrinkage of cell (correct)
  • Maintenance of plasma membrane integrity
  • Organelles are broken down and reused as nutrients
  • Does not always result in cell death

What can cause cells to die?

  • High oxygen levels
  • UV (correct)
  • Increased ATP production
  • Low glucose levels

What is a result of ischemia/reperfusion?

<p>Death of surrounding cells (C)</p> Signup and view all the answers

What is a characteristic of autophagy?

<p>Organelles are broken down and reused as nutrients (B)</p> Signup and view all the answers

Which process involves the release of cell contents into surrounding tissue?

<p>Necrosis (A)</p> Signup and view all the answers

What is a characteristic of apoptosis?

<p>Shrinkage of cell (A)</p> Signup and view all the answers

Which process involves the breakdown and reuse of organelles as nutrients?

<p>Autophagy (B)</p> Signup and view all the answers

What is a result of ischemia/reperfusion?

<p>Death of surrounding cells (B)</p> Signup and view all the answers

What signals the cell to die in response to factors like UV and cytotoxic T-cells?

<p>Cell death signals (A)</p> Signup and view all the answers

How are signals transmitted to the nucleus for cell division?

<p>Via signal transduction and mitogenic signalling pathways (B)</p> Signup and view all the answers

What maintains the balance in cell proliferation and inhibition in tissues?

<p>External stimuli and normal tissue restoration (D)</p> Signup and view all the answers

What characterises receptor tyrosine kinases (RTKs) and their activation?

<p>Cytoplasmic tyrosine kinase domain phosphorylates peptides when ligands bind (B)</p> Signup and view all the answers

What happens when a cell receives a mitogenic signal?

<p>Activated protein translation and pathways for energy production, anabolic metabolism, and creation of organelles (A)</p> Signup and view all the answers

How does oncogenic activation of p21 RAS influence cell proliferation?

<p>Stimulates excessive proliferation by amplifying signals (A)</p> Signup and view all the answers

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