5 Questions
What are the signals that induce cell division, and how are they transmitted to the nucleus?
Growth factors and mitogens; signals are relayed to the nucleus via signal transduction
What happens when a cell receives a mitogenic signal?
Activated protein translation and pathways for energy production, anabolic metabolism, and creation of organelles
What maintains the balance in cell proliferation and inhibition in tissues?
Proliferates only via external stimuli and stops when normal tissue is restored
Can you explain the pathway of mitogenic signalling in more detail?
Receptor on p.m. binds to mitogen → signal amplified by second messengers → signal reaches nucleus → gene expression
What characterises receptor tyrosine kinases (RTKs) and their activation?
Cytoplasmic tyrosine kinase domain phosphorylates peptides when ligands bind (activation → dimerization) creating docking sites for adaptor proteins to propagate signals
Test your knowledge on the signals that induce cell division, how they are transmitted to the nucleus, and the maintenance of balance in cell proliferation and inhibition in tissues.
Make Your Own Quizzes and Flashcards
Convert your notes into interactive study material.
Get started for free
