Cell Division Signals and Signal Transduction Quiz
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Questions and Answers

What are the signals that induce cell division, and how are they transmitted to the nucleus?

  • Nutrients and oxygen; signals are transmitted to the nucleus through endocytosis
  • Toxins and pathogens; signals are transmitted to the nucleus via passive diffusion
  • Growth factors and mitogens; signals are relayed to the nucleus via signal transduction (correct)
  • Hormones and neurotransmitters; signals are directly transmitted to the nucleus
  • What happens when a cell receives a mitogenic signal?

  • Activated protein translation and pathways for energy production, anabolic metabolism, and creation of organelles (correct)
  • Cell enters a dormant state and stops all metabolic activities
  • Cell membrane ruptures due to excessive signal amplification
  • Cell undergoes programmed cell death (apoptosis)
  • What maintains the balance in cell proliferation and inhibition in tissues?

  • Cells undergo uncontrolled proliferation regardless of the tissue state
  • -ve regulations (TSGs) often inactivated by mutations/epigenetic effects
  • Proliferates only via external stimuli and stops when normal tissue is restored (correct)
  • +ve regulators (from proto-oncogenes) might become oncogene when activated by mutations/epigenetic effects
  • Can you explain the pathway of mitogenic signalling in more detail?

    <p>Receptor on p.m. binds to mitogen → signal amplified by second messengers → signal reaches nucleus → gene expression</p> Signup and view all the answers

    What characterises receptor tyrosine kinases (RTKs) and their activation?

    <p>Cytoplasmic tyrosine kinase domain phosphorylates peptides when ligands bind (activation → dimerization) creating docking sites for adaptor proteins to propagate signals</p> Signup and view all the answers

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