Podcast
Questions and Answers
What are the signals that induce cell division, and how are they transmitted to the nucleus?
What are the signals that induce cell division, and how are they transmitted to the nucleus?
- Nutrients and oxygen; signals are transmitted to the nucleus through endocytosis
- Toxins and pathogens; signals are transmitted to the nucleus via passive diffusion
- Growth factors and mitogens; signals are relayed to the nucleus via signal transduction (correct)
- Hormones and neurotransmitters; signals are directly transmitted to the nucleus
What happens when a cell receives a mitogenic signal?
What happens when a cell receives a mitogenic signal?
- Activated protein translation and pathways for energy production, anabolic metabolism, and creation of organelles (correct)
- Cell enters a dormant state and stops all metabolic activities
- Cell membrane ruptures due to excessive signal amplification
- Cell undergoes programmed cell death (apoptosis)
What maintains the balance in cell proliferation and inhibition in tissues?
What maintains the balance in cell proliferation and inhibition in tissues?
- Cells undergo uncontrolled proliferation regardless of the tissue state
- -ve regulations (TSGs) often inactivated by mutations/epigenetic effects
- Proliferates only via external stimuli and stops when normal tissue is restored (correct)
- +ve regulators (from proto-oncogenes) might become oncogene when activated by mutations/epigenetic effects
Can you explain the pathway of mitogenic signalling in more detail?
Can you explain the pathway of mitogenic signalling in more detail?
What characterises receptor tyrosine kinases (RTKs) and their activation?
What characterises receptor tyrosine kinases (RTKs) and their activation?
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