Cell Cycle Regulators in Bone Development and Regeneration

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Questions and Answers

Which cell processes can cell cycle regulators influence?

  • Cell migration
  • Cell differentiation (correct)
  • Protein synthesis
  • DNA replication

What is the role of p21, a cell cycle regulator, in bone healing/development cascade?

  • Reduces bone formation
  • Inhibits bone mineral density
  • Enhances bone repair capacity (correct)
  • Promotes cancerogenesis

What effect does inhibition of p27, a cell cycle regulator, have on bone mineral density and bone formation?

  • Causes cancerogenesis
  • Has no effect on bone mineral density and bone formation
  • Increases bone mineral density and bone formation (correct)
  • Decreases bone mineral density and bone formation

What is the main focus of the reviewed study?

<p>Role of p21 in bone development (C)</p>
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What is the relationship between cell cycle regulators and cancerogenesis?

<p>Cell cycle regulators prevent cancerogenesis (B)</p>
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Which of the following is NOT a cell process influenced by cell cycle regulators?

<p>DNA replication (B)</p>
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What was the effect of deleting p21, a cell cycle regulator, in the study?

<p>Increased bone repair capacity (D)</p>
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Which cell cycle regulator was shown to increase bone mineral density and bone formation when inhibited?

<p>p27 (B)</p>
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What is the main focus of the reviewed study?

<p>Cell cycle regulators and bone development/regeneration (D)</p>
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Which type of cells are influenced by cell cycle regulators according to the text?

<p>Osteoblasts (A)</p>
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