Cell Cycle Regulators Quiz
18 Questions
1 Views

Choose a study mode

Play Quiz
Study Flashcards
Spaced Repetition
Chat to lesson

Podcast

Play an AI-generated podcast conversation about this lesson

Questions and Answers

What happens when a proto-oncogene mutates or becomes overactive?

  • It promotes cell death (apoptosis).
  • It transforms into an oncogene, causing cells to divide out of control. (correct)
  • It stops cells from growing and dividing.
  • It becomes a tumor suppressor gene.
  • How can gene variants/mutations contribute to proto-oncogenes becoming oncogenes?

  • By activating proto-oncogenes. (correct)
  • By causing DNA sequence changes during cell division.
  • By preventing chemical modifications.
  • By turning off the gas pedal.
  • Which process can turn on proto-oncogenes without altering the gene sequence?

  • Chromosome rearrangements
  • Tumor suppression
  • Epigenetic changes (correct)
  • Gene recombination
  • What is the role of tumor suppressor genes in cell growth?

    <p>Preventing cell growth and division</p> Signup and view all the answers

    Which component is critical for proto-oncogenes to function as 'gas pedals' in cell growth?

    <p>Cyclin B</p> Signup and view all the answers

    How does the activation of MPF influence the cell cycle progression?

    <p>It initiates entry into mitosis from G2 phase.</p> Signup and view all the answers

    What type of mutation involves big rearrangements of DNA segments, like genetic remodelling projects?

    <p>Large-scale mutations</p> Signup and view all the answers

    Which type of small-scale mutation involves adding or removing nucleotide pairs, similar to editing a sentence by adding or deleting words?

    <p>Insertions</p> Signup and view all the answers

    In a substitution mutation, what happens when a single nucleotide pair is changed in the genetic code?

    <p>It may not affect the amino acid encoded</p> Signup and view all the answers

    What type of mutation does not change the protein's appearance but may transform one codon into another that still codes for the same amino acid?

    <p>Silent mutations</p> Signup and view all the answers

    Which type of small-scale mutation might result in a protein with a new amino acid that behaves similarly to the old one?

    <p>Missense mutations</p> Signup and view all the answers

    Imagine a mutation where one codon is changed into another that codes for a different amino acid. This is an example of:

    <p>Missense mutation</p> Signup and view all the answers

    What is the consequence of a frameshift mutation near the end of a gene?

    <p>The resulting protein is likely to be nonfunctional</p> Signup and view all the answers

    How do insertions and deletions outside of coding regions impact gene expression?

    <p>They still significantly shape how genes function</p> Signup and view all the answers

    In sickle-cell disease, what specific type of mutation occurs in the DNA?

    <p>Point mutation</p> Signup and view all the answers

    What is the consequence of the mutation in the beta-globin gene in sickle-cell disease?

    <p>It alters the amino acid sequence in the hemoglobin protein</p> Signup and view all the answers

    What happens when altered hemoglobin in sickle-cell disease encounters low oxygen levels?

    <p>It forms long, rigid fibers</p> Signup and view all the answers

    How does a premature termination occur in relation to nonsense mutations?

    <p>When incorrect codons are grouped after an insertion or deletion</p> Signup and view all the answers

    More Like This

    Use Quizgecko on...
    Browser
    Browser