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Questions and Answers
What form does DNA take in non-dividing cells?
What form does DNA take in non-dividing cells?
Which function is NOT associated with the Smooth Endoplasmic Reticulum?
Which function is NOT associated with the Smooth Endoplasmic Reticulum?
What is the primary energy compound produced by the mitochondria?
What is the primary energy compound produced by the mitochondria?
What is the primary role of lysosomes?
What is the primary role of lysosomes?
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Which organelle is primarily responsible for packaging and transporting materials out of the cell?
Which organelle is primarily responsible for packaging and transporting materials out of the cell?
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What type of structures do microfilaments and microtubules form within the cell?
What type of structures do microfilaments and microtubules form within the cell?
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Which of the following statements about ribosomes is true?
Which of the following statements about ribosomes is true?
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In dividing cells, what form does DNA take?
In dividing cells, what form does DNA take?
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What is the primary function of the Na+ - K+ pump?
What is the primary function of the Na+ - K+ pump?
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Which of the following correctly defines exocytosis?
Which of the following correctly defines exocytosis?
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What mechanism is described as 'cell drinking'?
What mechanism is described as 'cell drinking'?
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During filtration, what factors influence the amount of fluid filtered per time unit?
During filtration, what factors influence the amount of fluid filtered per time unit?
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What is the primary distinction between ionizing and non-ionizable solutes in osmosis?
What is the primary distinction between ionizing and non-ionizable solutes in osmosis?
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Which of the following best describes the function of osmosis?
Which of the following best describes the function of osmosis?
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What is osmotic pressure?
What is osmotic pressure?
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What sequence of contractions occurs during the cardiac cycle?
What sequence of contractions occurs during the cardiac cycle?
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In which process do large particles enter the cell through membrane folding?
In which process do large particles enter the cell through membrane folding?
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What causes depolarization in cardiac muscle cells?
What causes depolarization in cardiac muscle cells?
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How is the electrical activity of the heart recorded?
How is the electrical activity of the heart recorded?
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What does Einthoven's triangle represent in electrocardiography?
What does Einthoven's triangle represent in electrocardiography?
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What is the function of the indifferent electrode in unipolar recording?
What is the function of the indifferent electrode in unipolar recording?
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Which of the following leads records the potential difference between the left leg and the right arm?
Which of the following leads records the potential difference between the left leg and the right arm?
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What occurs during diastole in the heart cycle?
What occurs during diastole in the heart cycle?
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Which unipolar lead configuration uses the right arm as the exploring electrode?
Which unipolar lead configuration uses the right arm as the exploring electrode?
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What role does the receptor play in the feedback loop?
What role does the receptor play in the feedback loop?
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Which statement accurately describes negative feedback loops?
Which statement accurately describes negative feedback loops?
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An example of a positive feedback loop is:
An example of a positive feedback loop is:
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What happens if homeostasis fails to compensate for a disturbance?
What happens if homeostasis fails to compensate for a disturbance?
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Which component of the feedback loop is responsible for sending output when changes are needed?
Which component of the feedback loop is responsible for sending output when changes are needed?
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Most feedback loops in the body are classified as which type?
Most feedback loops in the body are classified as which type?
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Which of the following is NOT a component of the feedback loop?
Which of the following is NOT a component of the feedback loop?
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Which process is an example of negative feedback?
Which process is an example of negative feedback?
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What is the primary role of the plasma membrane?
What is the primary role of the plasma membrane?
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Which part of the phospholipid molecule is hydrophilic?
Which part of the phospholipid molecule is hydrophilic?
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What describes the state of homeostasis in the human body?
What describes the state of homeostasis in the human body?
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Which components make up the structure of the plasma membrane?
Which components make up the structure of the plasma membrane?
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In the fluid mosaic model of the plasma membrane, what does the term 'mosaic' refer to?
In the fluid mosaic model of the plasma membrane, what does the term 'mosaic' refer to?
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How do the hydrophilic and hydrophobic ends of phospholipids behave in the plasma membrane?
How do the hydrophilic and hydrophobic ends of phospholipids behave in the plasma membrane?
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What defines the structural and functional unit of life?
What defines the structural and functional unit of life?
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Which is NOT a characteristic described about cells?
Which is NOT a characteristic described about cells?
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What is the primary role of the sinoatrial node (SAN) in the heart?
What is the primary role of the sinoatrial node (SAN) in the heart?
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Which of the following best defines stroke volume (SV)?
Which of the following best defines stroke volume (SV)?
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What does preload refer to in cardiac physiology?
What does preload refer to in cardiac physiology?
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How is cardiac output (CO) calculated?
How is cardiac output (CO) calculated?
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What does the ejection fraction indicate?
What does the ejection fraction indicate?
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Which property allows cardiac muscle to initiate its beats independently of the nervous system?
Which property allows cardiac muscle to initiate its beats independently of the nervous system?
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What does the cardiac index relate to?
What does the cardiac index relate to?
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During which phase of the cardiac cycle does afterload act on the ventricles?
During which phase of the cardiac cycle does afterload act on the ventricles?
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Study Notes
General Characteristics of the Cardiovascular System
- The cardiovascular system is comprised of the heart and blood vessels
- The heart acts as a pressure pump
- The left ventricle pumps blood at high pressure to the systemic circulation
- The right ventricle pumps blood at lower pressure to the pulmonary circulation
- Semilunar valves regulate blood flow between the ventricles and blood vessels
Heart Chambers and Valves
- The heart has four chambers: two atria and two ventricles
- Atrioventricular (AV) valves (tricuspid and mitral) facilitate one-way blood flow from atria to ventricles
- Semilunar valves (aortic and pulmonary) regulate blood flow from ventricles to arteries
Organization of the Circulatory Systems
- Systemic circulation: carries oxygenated blood from the left ventricle around the body, where it releases oxygen and absorbs carbon dioxide, then returns to the right atrium
- Pulmonary circulation: carries deoxygenated blood from the right ventricle to the lungs, where it absorbs oxygen and releases carbon dioxide, before returning to the left heart
Blood Vessels
- Arteries carry blood away from the heart
- Veins carry blood toward the heart
- Capillaries facilitate the exchange of substances across the vessel wall
Blood Vessel Types and Functions
- Arteries: transport high-pressure blood from the heart.
- Arterioles: act as reservoirs of blood and transport low-pressure blood.
- Capillaries: facilitate gas exchange, nutrient transfer, and waste removal
- Venules: connect capillaries to veins.
- Veins: transport low-pressure blood toward the heart
Cardiac Cycle
- A repeating sequence of contraction and relaxation of the atria and ventricles.
- The sequence includes four phases: atrial systole, isovolumetric contraction, ejection, and isovolumetric relaxation
- Pressure changes in the heart chambers correlate with the opening and closing of heart valves
Cardiac Cycle Events
- Atrial systole: contraction of the atria causes a rise in atrial pressure, forcing blood into the ventricles
- Isovolumetric contraction: ventricular contraction increases pressure but volume remains the same until the pressure exceeds pressure of the pulmonary/aortic outflow valves.
- Ejection: when ventricular pressure exceeds pressure in the arteries, the outflow valves open, and blood is pumped out
- Isometric relaxation: ventricular relaxation leads to a decrease in ventricular pressure, closing the outflow valves, and then the heart is relaxed
Important Terms Relating to the Cardiac Cycle
- Preload: the load acting on the ventricle before contraction (determined by venous return or end-diastolic volume)
- Afterload: the load acting on the ventricle during contraction (determined by arterial resistance or total peripheral resistance)
Electrocardiography (ECG)
- A recording of the heart's electrical activity
- ECG recording represents the sum of electrical activity across the heart
- Electrodes placed on the body's surface detect these electrical changes
- ECG findings can help diagnose various cardiac abnormalities and conditions
Heart Rate Determination from ECG
- A normal ECG reading has a P wave, a PR interval, the QRS complex, and a T wave.
- The rate is determined by calculating the time between consecutive R peaks (RR interval)
Applications of ECG
- Arrhythmias: abnormal heart rhythms
- Disorders in the activation sequence: problems in conduction of electrical signals
- Myocardial ischemia and infarction: decreased blood flow to the heart muscle
- Electrolyte imbalance: irregular levels of certain electrolytes (e.g., potassium and calcium)
- Carditis (Pericarditis/Myocarditis)
- Pacemaker monitoring
Blood
- Fluid connective tissue
- Contains cells (RBCs, WBCs, platelets) suspended in a fluid matrix called plasma
- Cellular component includes red blood cells (erythrocytes), white blood cells (leukocytes) and platelets (thrombocytes).
- The liquid component includes water (90%), plasma proteins, lipids, hormones, enzymes, nutrients and waste products
Blood Classifications
- Blood grouped into O-A-B blood types, based on the presence or absence of A and B antigens (agglutinogens) on red blood cells.
- Rh factor; either the presence or absence of the Rh antigen (D antigen) on the red blood cells.
Erythropoiesis
- Process of formation of red blood cells (erythrocytes)
- Occurs in the bone marrow of adults (axial skeleton)
Erythropoiesis factors
- Essential factors for proper erythrocyte formation such as:
- Diet.
- Hormones.
- Iron.
- Cobalt
Anemia
- A condition caused by either a low RBC count or a low hemoglobin content, which decreases the blood's oxygen-carrying capacity;
- Etiological classification: hemorrhagic anemia (blood loss), decreased production of RBCs and hemolytic anemia (RBC destruction)
- Morphological classification: normocytic normochromic, microcytic hypochromic or macrocytic normochromic
WBC
- Leukocytes: mobile defense units formed both in the bone marrow and lymph tissue.
- Involved in immune response
- Variations in WBC count; Leukopenia (decreased count) or Leukocytosis (increased count)
- Leukocytes can be: neutrophils, lymphocytes, monocytes, eosinophils (allergic), and basophils (histamine)
- Leukemia; a cancer affecting bone marrow white blood cells.
Platelets (Thrombocytes)
- Function: clotting
- Platelet formation: megakaryocytes fragment in the bone marrow to form platelets when activated
- Platelet count variations; Thrombocytopenia
- Platelets in clotting: activation causes the formation of a platelet plug (temporary) and the definitive plug (coagulation)
Cardiovascular System (CVS)
- The circulatory system, composed of blood, the heart, and blood vessels, to transport blood and maintain homeostasis.
- Blood delivers essential nutrients, gases, and removes metabolic wastes.
- The heart pumps blood, and blood vessels transport it throughout the body.
- Important circulatory system components include arteries, veins, and capillaries.
Hemolytic Disease of the Newborn
- A condition that occurs when a mother is Rh-negative and a father is Rh-positive.
- Mother's antibodies attack fetus's Rh positive blood cells causing complications
- Prevention is possible by administering anti-D immunoglobulin
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Description
Test your knowledge on key concepts within cell biology, including the structure and function of organelles such as mitochondria, lysosomes, and the Smooth Endoplasmic Reticulum. This quiz covers important topics like DNA structure in dividing and non-dividing cells, osmosis, and the cardiac cycle. Perfect for students studying cell biology at any level.