Cell Biology Quiz
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Questions and Answers

Which of the following structures is not a component of the axoneme in cilia?

  • Basal bodies similar to centrioles (correct)
  • Nine peripheral doublets of microtubules
  • Two central singlets of microtubules
  • Shaft
  • Lipofuscin pigments are categorized as which type of cell inclusion?

  • Exogenous lipids
  • Exogenous pigments
  • Endogenous pigments (correct)
  • Stored food
  • Which of the following cell types naturally lacks a nucleus?

  • Red blood cells (correct)
  • Liver cells
  • Skeletal muscle cells
  • Epithelial cells
  • What is the primary function of euchromatin within the cell nucleus?

    <p>Directing protein synthesis (A)</p> Signup and view all the answers

    Which cellular structure is characterized by 9+2 arrangement of microtubules?

    <p>Axoneme (B)</p> Signup and view all the answers

    Which cellular component is responsible for generating the majority of a cell's ATP?

    <p>Mitochondria (B)</p> Signup and view all the answers

    What is the approximate thickness of the cell membrane?

    <p>9-10 nm (B)</p> Signup and view all the answers

    Which transport mechanism is responsible for the movement of glucose across the cell membrane?

    <p>Active transport (A)</p> Signup and view all the answers

    Which of the following is a function of the cell coat (glycocalyx)?

    <p>Facilitating cell adhesion (D)</p> Signup and view all the answers

    Which of the following is NOT a membranous organelle?

    <p>Ribosome (D)</p> Signup and view all the answers

    What type of molecules are transported across the cell membrane via passive diffusion?

    <p>Gases such as $O_2$ and $CO_2$ (A)</p> Signup and view all the answers

    Which process involves the engulfment of fluid droplets by the cell membrane?

    <p>Pinocytosis (C)</p> Signup and view all the answers

    What is the primary function of the sodium-potassium pump?

    <p>To maintain ion gradients across the cell membrane (C)</p> Signup and view all the answers

    Which of the following is a key function of the rough endoplasmic reticulum (RER)?

    <p>Chemical modifications of proteins synthesized (C)</p> Signup and view all the answers

    What is the primary distinction between primary and secondary lysosomes?

    <p>Primary lysosomes are newly formed from the Golgi, while secondary lysosomes are formed by primary lysosomes fusing with foreign vesicles. (A)</p> Signup and view all the answers

    Which type of cytoskeletal filament is primarily responsible for muscle contraction?

    <p>Thin filaments (actin) (A)</p> Signup and view all the answers

    What is the diameter of intermediate filaments?

    <p>10 nm (B)</p> Signup and view all the answers

    Which of the following is a function of intermediate filaments?

    <p>Support of cell shape (D)</p> Signup and view all the answers

    What protein primarily forms microtubules?

    <p>Tubulin (C)</p> Signup and view all the answers

    Centrioles are composed of how many triplets of microtubules?

    <p>9 (B)</p> Signup and view all the answers

    Which of the following is a function of microtubules?

    <p>Formation of cilia (D)</p> Signup and view all the answers

    What is the function of lysosomes?

    <p>Intracellular digestion (A)</p> Signup and view all the answers

    What is the diameter of microtubules?

    <p>25 nm (D)</p> Signup and view all the answers

    Which of the following is NOT a function of the smooth endoplasmic reticulum (SER)?

    <p>Protein synthesis for excretion outside the cell. (A)</p> Signup and view all the answers

    What is the primary function of ribosomes?

    <p>Protein synthesis. (B)</p> Signup and view all the answers

    Which of the following describes the structure of the Golgi apparatus?

    <p>A stack of 4-10 flattened saccules with convex and concave faces. (D)</p> Signup and view all the answers

    Where does the formation of ribosomes take place within the cell?

    <p>Nucleolus. (D)</p> Signup and view all the answers

    Which of the following best describes the function of the mitochondria?

    <p>ATP production. (B)</p> Signup and view all the answers

    A cell that is actively synthesizing proteins for secretion would likely have a large amount of which organelle?

    <p>Rough Endoplasmic Reticulum (RER). (A)</p> Signup and view all the answers

    What is the fate of secretory vesicles that arise from the mature face of the Golgi apparatus?

    <p>They discharge their contents outside the cell or remain to form lysosomes. (C)</p> Signup and view all the answers

    What is the name given to the spaces formed by the membranes of the mitochondria?

    <p>Intermembranous space and matrix space. (B)</p> Signup and view all the answers

    Which staining technique is required to visualize the Golgi apparatus using light microscopy?

    <p>Silver staining (C)</p> Signup and view all the answers

    What is the role of transfer vesicles in the Golgi apparatus?

    <p>To transport proteins from the RER to the Golgi. (B)</p> Signup and view all the answers

    Flashcards

    Respiratory Epithelium

    Tissue found in trachea and bronchi that aids in respiration.

    Cell Inclusions

    Non-living materials stored in the cytoplasm, including food and pigments.

    Exogenous Pigments

    Pigments from external sources, e.g., carotene in vegetables or tattoo ink.

    Nucleus Shapes

    Various forms of the nucleus: spherical, oval, kidney-shaped, segmented, horse shoe.

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    Euchromatin vs Heterochromatin

    Euchromatin is active and extended; heterochromatin is inactive and condensed.

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    Cytoplasm

    The gel-like substance inside a cell excluding the nucleus, containing organelles and inclusions.

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    Membranous organelles

    Organelles surrounded by a membrane, such as mitochondria and the Golgi apparatus.

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    Cell membrane thickness

    The cell membrane is about 9-10 nm thick and appears as a thin line under an electron microscope.

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    Phospholipids

    Lipid molecules that form the basic structure of the cell membrane, with hydrophilic heads and hydrophobic tails.

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    Active transport

    The process requiring energy to move materials across the cell membrane against their concentration gradient.

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    Endocytosis

    The process of transporting materials into the cell by engulfing them.

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    Mitochondria

    Membranous organelles known as the powerhouse of the cell, producing energy.

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    Cell coat functions

    Components related to the cell surface that aid in adhesion, hormone response, and immunity.

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    Functions of Golgi Apparatus

    Chemical modifications, packaging, and secretion of proteins; forms vesicles and lysosomes.

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    Lysosomes

    Membranous organelles containing hydrolytic enzymes; involved in digestion and waste processing.

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    Primary Lysosomes

    Newly formed lysosomes that originate from the Golgi apparatus.

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    Secondary Lysosomes

    Formed from primary lysosomes merging with foreign vesicles to digest contents.

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    Microfilaments

    Contractile filaments, 7 nm thick, involved in muscle contraction and cell shape support.

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    Thick Filaments

    Myosin filaments thicker than thin filaments (12-16 nm), associated with actin in muscles.

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    Microtubules

    25 nm pipe-like structures made of tubulin, supporting cell shape and transport.

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    Centrioles

    Pair of structures in the centrosome, each made of 9 triplets of microtubules, perpendicular to each other.

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    Cilia

    Hair-like processes on the surface of cells, involved in movement and sensation.

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    Intermediate Filaments

    10 nm thick filaments that support cell shape and transmit forces, but do not contract.

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    Inter-membranous space

    The space located between the outer and inner membrane of mitochondria.

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    Matrix space

    The innermost compartment of mitochondria, containing DNA, RNA, and proteins.

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    Ribosomes

    Non-membranous organelles involved in protein synthesis, formed of rRNA and proteins.

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    Rough Endoplasmic Reticulum (RER)

    Type of ER with attached ribosomes, involved in protein synthesis to be secreted.

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    Smooth Endoplasmic Reticulum (SER)

    Type of ER without ribosomes, involved in lipid synthesis, detoxification, and calcium regulation.

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    Golgi apparatus

    Organelle composed of sacs that modifies, sorts, and packages proteins.

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    Polysome

    A cluster of ribosomes linked by mRNA during protein synthesis.

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    Secretory vesicles

    Vesicles that discharge their contents outside the cell or form lysosomes.

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    Cristae

    Folded inner membrane of mitochondria, increasing surface area for ATP production.

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    Study Notes

    Cell Structure and Function

    • Cell: The basic unit of life, possessing various organelles and structures.
    • Cytoplasm: The gel-like substance filling the cell.
    • Cytoplasmic contents: Comprised of organelles, inclusions, and cell matrix.
    • Organelles: Specialized structures with specific functions within the cytoplasm.
    • Membrane-bound organelles: Mitochondria, Golgi apparatus, lysosomes, endoplasmic reticulum, peroxisomes, and cytoplasmic vesicles.
    • Non-membrane-bound organelles: Ribosomes and cytoskeleton.
    • Cell membrane (Plasma membrane): A thin, flexible outer layer of the cell that regulates the passage of materials into and out of the cell.
      • 9-10 nm thick
      • Not visible in light microscopy
      • Trilaminar (3 layers) in electron microscopy
    • Chemical structure of cell membrane: Composed of lipids (phospholipids and cholesterol), proteins (integral and peripheral), and carbohydrates (glycoproteins and glycolipids).
    • Functions of cell membrane:
      • Exchanges of materials
      • Endocytosis (Phagocytosis for solid, Pinocytosis for fluids)
      • Exocytosis
      • Sodium-potassium pump
      • Functions of cell coat

    Mitochondria

    • Definition:
      • Membrane-bound organelles.
      • Powerhouse of the cell responsible for energy production.
    • Structure (L.M.): Rods, granules, filaments
    • Structure (E.M.): Rod-shaped or spherical, covered by two membranes.
      • Outer membrane: smooth
      • Inner membrane: forms cristae. Has an inter membranous space.
      • Matrix space: contains DNA, RNA, ribosomes, and proteins.
    • Function: Produce ATP (energy).
    • Number: Variable depending on cell type and function.

    Ribosomes

    • Definition:
      • Non-membrane-bound organelles.
      • Sites of protein synthesis.
    • Structure (L.M.): Basophilic (RNA containing)
    • Structure (E.M.):
      • Small particles, two subunits (large and small)
      • Composed of rRNA and proteins.
      • Formed within nucleolus.
      • Released through nuclear pores
    • Function: Protein synthesis.
    • Types: Free ribosomes (protein synthesis into cytosol) and attached ribosomes (protein synthesis for secretion or incorporation into membranes).

    Endoplasmic Reticulum (ER)

    • Types:

      • Rough ER (RER): studded with ribosomes; involved in protein synthesis destined for secretion or membrane incorporation.
      • Smooth ER (SER): lacks ribosomes; involved in lipid synthesis, detoxification, carbohydrate metabolism.
    • Structure (EM): Interconnecting tubules and cisternae (flattened sacs) to form a network.

    • Function (RER): Protein synthesis, particularly proteins destined for transport or secretion.

    • Function (SER): Synthesis of steroid hormones, glycogen metabolism, detoxification of toxins, and regulation of calcium in skeletal muscles.

    Golgi Apparatus

    • Structure (LM): Pale area near nucleus in routine stains; visible with silver staining
    • Structure (EM): Composed of flattened sacs called saccules, transfer vesicles, secretory vesicles
    • Function:
      • Chemical modification of proteins synthesized by ER.
      • Packaging of proteins into vesicles (for secretion).
      • Secretion of proteins (vesicles move along cytoskeleton to plasma membrane).
      • Formation of coated vesicles and lysosomes.

    Lysosomes

    • Definition: Membrane-bound organelles containing hydrolytic enzymes.
    • Structure: Round, electron-dense bodies.
    • Types:
      • Primary lysosomes: Newly formed lysosomes coming from the Golgi.
      • Secondary lysosomes: Primary lysosomes fused with other vesicles to digest material.
    • Function:
      • Phagocytosis of foreign particles/bacteria
      • Pinocytosis & digestion of fluids
      • Digestion/breakdown of old organelles.

    Cytoskeleton

    • Components: Microtubules, microfilaments, and intermediate filaments.
    • Microtubules (25nm): Pipe-like structures, made from tubulin protein.
      • Function: Support cell shape, transport substances, form cilia/flagella/centrioles, mitotic spindle.
    • Microfilaments (7 nm ): Thin, contractile filaments (actin).
      • Function: Muscle contraction, support for microvilli, cleavage furrow during cell division.
    • Intermediate filaments (10nm): Support cell shape, transmission of forces (smooth muscles), and involved in tumor identification.

    Centrioles and Centrosome

    • Structure: Paired perpendicular centrioles (made of microtubules).
    • Function: Organize microtubules for cell division (mitotic spindles) and basal bodies for cilia.

    Cilia

    • Definition: Hair-like projections on the cell surface.
    • Structure: 9 peripheral microtubule doublets and 2 central microtubules.
    • Function: Movement of fluids/substances across the cell surface
    • Location: Respiratory system, female reproductive system

    Cell Inclusions

    • Definition: Non-living materials stored in the cytoplasm.
    • Types:
      • Stored food (glycogen, lipids)
      • Pigments (exogenous and endogenous)

    Nucleus

    • Structure (LM):
      • Number: Single (mononucleated), binucleated, multinucleated, or anucleated.
      • Size: Variable (3-14 µm)
      • Shape: Spherically, oval, kidney-shaped, lobed (segmented), horse-shoe shaped.
      • Staining: Basophilic (due to DNA and RNA).
      • Appearance: Open-face (vesicular) or condensed.
    • Structure (EM): Nuclear envelope (membrane), nucleolus, chromatin, nuclear sap.

    Chromatin

    • Definition: Basophilic material forming chromosomes.
    • Structure: Nucleoprotein (DNA + histone proteins)
    • Types: Euchromatin (extended, active) and heterochromatin (condensed, inactive).

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    KSA Pharm Cell Biology 2025 PDF

    Description

    Test your knowledge on various aspects of cell biology including cellular structures, functions, and processes. This quiz covers topics such as axoneme components, cell inclusions, and membrane transport mechanisms. Challenge yourself with questions about the intricacies of cellular components and their roles.

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