Cell Biology Quiz: Diffusion and Apoptosis
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Questions and Answers

Which process specifically involves the movement of water molecules across a semipermeable membrane?

  • Diffusion
  • Metastasis
  • Osmosis (correct)
  • Apoptosis
  • A benign tumor is characterized by uncontrolled cell division and the ability to spread to other parts of the body.

    False (B)

    What is the term for a substance or agent that can cause cancer?

    Carcinogen

    A cell that enters a resting state because it doesn't pass the G1 checkpoint is said to be in the _____ state.

    <p>G0</p> Signup and view all the answers

    Match the following terms with their descriptions:

    <p>Diffusion = Movement of molecules from high to low concentration Mutation = A permanent change in a cell's DNA Contact inhibition = Normal cells stop dividing when crowded Apoptosis = Programmed cell death</p> Signup and view all the answers

    Which of the following best describes the process of metastasis?

    <p>The spread of cancer cells to other parts of the body. (D)</p> Signup and view all the answers

    All mutations in a cell's DNA directly lead to the development of cancer.

    <p>False (B)</p> Signup and view all the answers

    Cancer cells lose their ______ ______, which is when normal cells stop dividing when they get too close to each other.

    <p>contact inhibition</p> Signup and view all the answers

    What is assessed at the G1 checkpoint?

    <p>Cell size, nutrient levels, molecular signals, and DNA integrity (C)</p> Signup and view all the answers

    If a cell has irreparable DNA damage at the G2 checkpoint, it will proceed to mitosis.

    <p>False (B)</p> Signup and view all the answers

    During which phase of mitosis does the spindle checkpoint occur?

    <p>metaphase</p> Signup and view all the answers

    Cancer cells lose ___________, which is a characteristic of normal cells.

    <p>contact inhibition</p> Signup and view all the answers

    Match the following cancer treatments with their mechanism:

    <p>Surgery = Physical removal of cancerous tissue Chemotherapy = Drugs that slow or stop cell division and spread Radiation therapy = Damages the DNA of the cancer cells Immunotherapies = Stimulates immune system to attack cancer cells</p> Signup and view all the answers

    Which of the following is NOT a characteristic of cancer cells?

    <p>Contact inhibition (C)</p> Signup and view all the answers

    Cancer cells typically have a small cytoplasm and multiple nuclei.

    <p>True (A)</p> Signup and view all the answers

    What is a potential side effect of chemotherapy that is related to hair follicle cells?

    <p>hair loss</p> Signup and view all the answers

    Which of these is NOT a characteristic of living things as described by MRS GREN?

    <p>Digestion (A)</p> Signup and view all the answers

    According to the cell theory, all cells come from non-living material.

    <p>False (B)</p> Signup and view all the answers

    What is the primary function of the mitochondria?

    <p>To make energy for the cell through cellular respiration.</p> Signup and view all the answers

    The cell membrane is described as being ______, which means it controls which substances can pass in and out of the cell.

    <p>semi permeable</p> Signup and view all the answers

    Match the following organelles with their primary function:

    <p>Nucleus = Controls cell activities, holds DNA Ribosomes = Create proteins Lysosome = Breaks down waste and bacteria Golgi Apparatus = Processes and packages proteins</p> Signup and view all the answers

    What is the correct order of the level of organization of living things from simplest to most complex?

    <p>Organelles → Cells → Tissues → Organs → Organ Systems → Organism (D)</p> Signup and view all the answers

    Plant cells have centrioles to assist with cell division.

    <p>False (B)</p> Signup and view all the answers

    What is the name of the process where cancer cells spread to other parts of the body?

    <p>Metastasis</p> Signup and view all the answers

    The ______ contains chlorophyll and is the site of photosynthesis.

    <p>chloroplast</p> Signup and view all the answers

    Which of these is NOT a function of vacuoles?

    <p>Store DNA (D)</p> Signup and view all the answers

    Which of the following structures are found in plant cells but not in animal cells?

    <p>Chloroplast (D)</p> Signup and view all the answers

    Prokaryotic cells are generally larger and more complex than eukaryotic cells.

    <p>False (B)</p> Signup and view all the answers

    What is the main reason cells divide when they reach a certain size?

    <p>To maintain a sufficient surface area to volume ratio for efficient transport of nutrients and waste.</p> Signup and view all the answers

    During the synthesis phase of interphase, ______ replication occurs.

    <p>DNA</p> Signup and view all the answers

    Match the following phases of mitosis with their descriptions:

    <p>Prophase = Chromatin condenses into chromosomes; nuclear membrane breaks down Metaphase = Chromosomes line up in the middle of the cell Anaphase = Sister chromatids are pulled apart to opposite poles Telophase = Two new nuclei form and chromatids decondense</p> Signup and view all the answers

    Which of the following is NOT a reason cells divide?

    <p>To decrease the S:V ratio (B)</p> Signup and view all the answers

    Cytokinesis is the stage where the nucleus of the cell divides.

    <p>False (B)</p> Signup and view all the answers

    What is the structure that attaches sister chromatids together?

    <p>centromere</p> Signup and view all the answers

    In animal cells, the cytoplasm splits during cytokinesis through a process called ______.

    <p>cleavage furrow</p> Signup and view all the answers

    What is the purpose of the G1 checkpoint in the cell cycle?

    <p>To determine if the cell should divide or not (C)</p> Signup and view all the answers

    Flashcards

    Diffusion

    The movement of molecules from an area of high concentration to an area of lower concentration. This can occur through a semipermeable membrane but is not always required.

    Osmosis

    The movement of water molecules from an area of high water concentration to an area of low water concentration. This movement always occurs through a semipermeable membrane until equilibrium is reached.

    Apoptosis

    Programmed cell death where a cell self-destructs during the G2 checkpoint of cell division. This occurs when DNA damage is irreparable.

    G0 - resting state

    A resting state entered by a cell when it doesn't pass the G1 checkpoint of cell division. The cell waits for conditions to become favorable for replication.

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    Mutation

    A permanent change in the cell's DNA sequence. This can alter cell division signals and may lead to cancer.

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    Carcinogen

    Any substance, organism, or agent that can cause cancer. Examples include UV light, radiation, and certain chemicals.

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    Benign

    A non-cancerous tumor that is contained and does not spread. Cell division is controlled and occurs at a moderate pace.

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    Malignant

    A dangerous tumor that is cancerous. Cell division is uncontrolled and occurs rapidly. Cancer cells spread and damage surrounding tissues.

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    Movement

    The ability of an organism to move, bend, sway, or relocate.

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    Respiration

    The process by which organisms take in oxygen and release carbon dioxide.

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    Sensitivity

    The ability of an organism to detect and respond to changes in the environment.

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    Growth

    The ability of an organism to increase in size.

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    Reproduction

    The ability of an organism to produce offspring.

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    Excretion

    The ability of an organism to remove cellular waste products.

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    Nutrition

    The ability of an organism to take in nutrients and use them for energy, growth, and development.

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    Death

    All organisms have a limited lifespan.

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    Cell

    The basic unit of life. Made up of organelles.

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    Organelle

    Tiny organelles within a cell that perform specific functions.

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    Prokaryotes

    Prokaryotes are single-celled organisms that lack a membrane-bound nucleus and other organelles. They are generally smaller and simpler than eukaryotic cells.

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    Eukaryotes

    Eukaryotes are organisms that have a membrane-bound nucleus and other organelles. They can be single-celled or multicellular and are more complex than prokaryotes.

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    Cell Cycle

    The cell cycle is the process by which cells grow and divide. It consists of two main phases: interphase and mitosis.

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    Interphase

    Interphase is the stage in the cell cycle where the cell grows and duplicates its DNA. It is divided into three phases: G1, S, and G2.

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    Mitosis

    Mitosis is the process of cell division where the nucleus divides into two identical nuclei. It is subdivided into four main phases: prophase, metaphase, anaphase, and telophase.

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    G1 Checkpoint

    The G1 checkpoint is a critical point in the cell cycle where the cell decides whether to divide or not. If the cell is healthy and has enough resources, it progresses to the S phase.

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    Prophase

    Prophase is the first stage of mitosis where the chromatin condenses into chromosomes, the nuclear membrane breaks down, and centrioles move to opposite poles.

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    Metaphase

    Metaphase is the second stage of mitosis where the chromosomes line up at the center of the cell.

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    Anaphase

    Anaphase is the third stage of mitosis where the sister chromatids of each chromosome are pulled apart to opposite poles.

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    Telophase

    Telophase is the final stage of mitosis where the chromosomes arrive at the poles, the nuclear membrane reforms, and two identical daughter nuclei are formed.

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    Spindle Checkpoint (M Checkpoint)

    A checkpoint that occurs during mitosis, specifically during metaphase. It ensures that all sister chromatids are correctly attached to spindle fibers from opposite poles of the cell, ensuring proper chromosome separation during anaphase. This step is crucial to avoid errors in cell division.

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    Loss of Contact Inhibition

    A characteristic of cancer cells where they ignore the signals from neighboring cells that normally limit their growth and proliferation. They continue to divide uncontrollably even when they bump into other cells.

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    Metastasis

    The ability of cancer cells to break away from the original tumor mass and travel to other parts of the body, where they can establish new tumors. This is a defining characteristic of aggressive cancers.

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    Lack of Specialization in Cancer Cells

    Cancer cells undergo a decrease in specialization; they lose their normal functions and don't contribute to the body's tissues or systems. They become selfish, focusing solely on their own survival and growth.

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    Abnormal Structure of Cancer Cells

    A characteristic of cancer cells showing an abnormal structure with several changes: a small cytoplasm, large nuclei, coarse chromatin (condensed chromosomes), and a reduced number of cells in interphase.

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    Chemotherapy

    The use of drugs that inhibit or slow down the growth and spread of cancer cells by interfering with cell division. It can also affect normal, healthy cells, causing side effects.

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    Radiation Therapy

    A cancer treatment that uses high-energy waves or radioactive sources to damage cancer cells' DNA, inhibiting their further replication. It targets specific areas to minimize harm to healthy tissues.

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    Study Notes

    Diffusion

    • Movement of molecules from high concentration to low concentration
    • Can occur across semi-permeable membranes or not

    Osmosis

    • Movement of water molecules from high water concentration to low water concentration
    • Occurs across a semi-permeable membrane
    • Continues until equilibrium is reached

    Apoptosis

    • "Cellular suicide"
    • A cell kills itself during the G2 checkpoint
    • Irreversible DNA damage
    • Programmed cell death

    Go-resting state

    • If a cell does not pass the G1 checkpoint, it may enter a resting state
    • Delays replication until conditions improve

    Mutation

    • A permanent change in a cell's DNA
    • All cancers begin with a mutation
    • Mutations affect how the cell responds to division signals
    • Can be passed to other cells through mitosis (but not all cause cancer)

    Carcinogen

    • Substances, organisms, or agents that can cause cancer
    • Examples: chemicals, radiation, infectious agents

    Benign Tumor

    • Harmless tumor
    • Cell division is controlled
    • Slow-growing
    • Not invasive, does not spread

    Malignant Tumor

    • Cancerous tumor
    • Uncontrolled cell division
    • Rapid growth
    • Invasive, spreads to other parts of the body

    Contact Inhibition

    • Normal Cells: Cells stop dividing when they come into contact with other cells
    • Cancer Cells: Cells lose contact inhibition, continue to divide even when crowded

    Metastasis

    • Cancer cells detach from original tumor
    • Move and divide in other parts of the body
    • Makes treatment harder

    MRS GREND

    • Movement - ability to move
    • Respiration - cellular respiration to produce energy
    • Sensitivity - ability to detect and respond to changes in the environment
    • Growth - increase in size
    • Reproduction - producing offspring
    • Excretion - removing waste
    • Nutrition - obtaining food for energy and growth
    • Death - all organisms have a limited lifespan

    Cell Theory

    • Organisms are composed of one or more cells
    • Cells are the basic unit of structure and organization in living things
    • Cells come only from pre-existing cells

    Organelles

    • Nucleus - controls cell activity, houses DNA;
    • Centrioles - involved in cell division.

    Cytoplasm

    • Jelly like substance
    • surrounds and cushions organelles
    • Maintains internal pressure for chemical reactions

    Cell Membrane

    • thin and flexible surrounds the cell
    • controls flow of materials in and out of the cell (semi-permeable)

    Mitochondria

    • oval with folds
    • produces energy for cell through cellular respiration

    Golgi Apparatus

    • pancake stack with Protein
    • processes and packages protein for shipment

    Endoplasmic Reticulum

    • Rough or Smooth
    • Rough has ribosomes attached which synthesis proteins
    • Smooth Synthesizes or transports fats

    Ribosomes

    • Small round dots with no membrane
    • Create proteins
    • break down waste and bacteria

    Vacuoles

    • Liquid-filled space with a thin membrane
    • stores water, food and waste

    Cell Wall

    • Thick layer of cellulose (plants only)
    • protects and supports the cell

    Chloroplast

    • Small green discs containing chlorophyll (plants only)
    • Site of photosynthesis

    Animal Cell vs Plant Cell

    • Animal cells have centrioles and plant cells do not.
    • Plant cells have a cell wall and vacuole.
    • Both cells have a nucleus, membrane, cytoplasm, and other organelles.

    Prokaryotic vs Eukaryotic Cells

    • Prokaryotic: always unicellular, no membrane-bound organelles, simple structure, bacteria, archaea.
    • Eukaryotic: unicellular or multicellular, many membrane-bound organelles, complex structure, animals, plants, fungi, protists.

    Reasons for Cell Division

    • Reproduction: passing DNA from one generation to the next
    • Growth: the increase/division of cells is needed for organisms grow
    • Repair: damaged cells need to be replaced.

    Cell Cycle

    • G1: growth and preparation for DNA replication
    • S: DNA replication
    • G2: preparation for mitosis
    • M: mitosis (prophase, metaphase, anaphase, telophase)

    Prophase

    • Chromatin condenses into chromosomes.
    • Centrioles move to opposite ends of the cell.
    • Nuclear membrane starts to break down.
    • Spindle fibers appear.

    Metaphase

    • Chromosomes line up in the middle of the cell, attached to spindle fibers.

    Anaphase

    • Sister chromatids separate and move to opposite ends of the cell.

    Telophase

    • Chromosomes reach opposite ends of the cell.
    • Nuclear membranes reform.
    • Chromosomes de-condense.
    • Spindle fibers disappear.

    Cytokinesis

    • Cytoplasm divides, creating two new daughter cells.

    Stages for Cell Division Checkpoints

    • Cell size, nutrient availability, molecular signals, and DNA integrity (G1)
    • DNA replication completeness (G2)
    • Attachment of each chromosome to the spindle fibers (M)

    Characteristics in Cancer Cells

    • loses contact inhibition
    • lack specialization
    • abnormal structures(many nuclei)
    • lack cytokinesis/interphase

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    Test your knowledge on key concepts of cell biology including diffusion, osmosis, apoptosis, and the role of mutations in cancer development. This quiz will challenge your understanding of cellular processes and their implications. Perfect for students studying biology at any level.

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