Cell Biology - Cell Communication Quiz

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Questions and Answers

Which characteristic of water contributes most to its ability to serve as a transport medium in biological systems?

  • High surface tension (correct)
  • High heat capacity
  • Neutral pH
  • Solvent properties

What is the main difference between diffusion and osmosis?

  • Osmosis stops at equilibrium, while diffusion continues indefinitely.
  • Diffusion occurs through a semi-permeable membrane, while osmosis does not.
  • Diffusion involves solutes, while osmosis exclusively involves water. (correct)
  • Diffusion can occur in gases only, while osmosis only occurs in liquids.

Which of the following statements about water's chemical nature is NOT true?

  • Water effectively promotes chemical reactions due to its solvent properties.
  • Water is a polar substance.
  • Water can dissolve many substances due to its polarity.
  • Water molecules are non-polar in nature. (correct)

What process involves the movement of solutes through a semi-permeable membrane to a solvent area of lower concentration?

<p>Dialysis (B)</p> Signup and view all the answers

Which property of water helps maintain body temperature through evaporation?

<p>High heat of vaporization (A)</p> Signup and view all the answers

What happens to a cell placed in a hypertonic solution?

<p>It loses water and undergoes plasmolysis. (B)</p> Signup and view all the answers

Which process involves the movement of water across a selectively permeable membrane?

<p>Osmosis (C)</p> Signup and view all the answers

Which type of transport requires energy to move substances against their concentration gradient?

<p>Active transport (C)</p> Signup and view all the answers

What is the primary characteristic of isotonic solutions?

<p>They have equal solute concentration compared to the cell. (D)</p> Signup and view all the answers

In facilitated diffusion, what is necessary for the movement of substances?

<p>Transport proteins (A)</p> Signup and view all the answers

What do acids do to blue litmus paper?

<p>Turn it pink. (C)</p> Signup and view all the answers

Which of the following correctly describes strong acids?

<p>They are completely ionised in solution. (D)</p> Signup and view all the answers

What is the expected pH for a basic (alkaline) solution?

<p>pH &gt; 7. (A)</p> Signup and view all the answers

What is the relationship between pH and hydrogen ion concentration?

<p>As pH increases, [H+] decreases exponentially. (A)</p> Signup and view all the answers

What is the composition of a salt formed from an acid-base reaction?

<p>Acid + base. (D)</p> Signup and view all the answers

Which of the following statements is true about weak acids?

<p>They are ionised to a small extent (&lt; 50%). (D)</p> Signup and view all the answers

What occurs when the pH of blood changes by more than half a pH unit?

<p>It leads to serious illness. (A)</p> Signup and view all the answers

What are the primary characteristics of salts at room temperature?

<p>They are ionic compounds and solid crystals. (A)</p> Signup and view all the answers

What is the primary function of electrolytes in living systems?

<p>To maintain hydration and facilitate muscle and nerve function (D)</p> Signup and view all the answers

Which of the following is NOT considered an electrolyte?

<p>Glucose (C)</p> Signup and view all the answers

What happens to the concentration of ions when an electrolyte solution is described as 'dilute'?

<p>It has a low concentration of ions (B)</p> Signup and view all the answers

Which of the following correctly describes an acid?

<p>It donates H+ ions and increases the H+ ion concentration (D)</p> Signup and view all the answers

Which of the following ions is NOT typically considered a primary electrolyte in physiology?

<p>Iron (Fe2+) (B)</p> Signup and view all the answers

What type of particle is formed when hydrochloric acid (HCl) dissociates in water?

<p>Chloride ion (Cl-) and Hydrogen ion (H+) (C)</p> Signup and view all the answers

Which statement about anions and cations is true?

<p>Cations are positively charged particles formed from atoms that lose electrons (C)</p> Signup and view all the answers

How does an electrolyte solution contribute to the process of an electrocardiogram (ECG)?

<p>Ions carry electrical signals that can be detected (D)</p> Signup and view all the answers

What level of biological organization is characterized by a group of similar cells and the materials surrounding them?

<p>Tissue Level (D)</p> Signup and view all the answers

Which of the following represents a macroscopic approach to studying anatomy?

<p>Regional Anatomy (C)</p> Signup and view all the answers

What is the primary function of negative feedback in biological systems?

<p>To stabilize variable levels around a set point (D)</p> Signup and view all the answers

Which branch of physiology specifically examines processes in the nervous system?

<p>Neurophysiology (D)</p> Signup and view all the answers

In which scenario is positive feedback typically harmful?

<p>After severe blood loss leading to decreased blood pressure (A)</p> Signup and view all the answers

What is the primary focus of histology within the field of microscopic anatomy?

<p>Study of tissues (A)</p> Signup and view all the answers

What describes the anatomical position of the body?

<p>Body erect, face forward, feet together, palms facing forward (B)</p> Signup and view all the answers

Which characteristic of life involves the ability to sense changes in the environment and adjust accordingly?

<p>Responsiveness (B)</p> Signup and view all the answers

Which anatomical approach involves examining body structures with the help of imaging techniques like X-rays?

<p>Surface Anatomy (B)</p> Signup and view all the answers

Which term refers to a change from a general state to a more specific state in an organism's development?

<p>Differentiation (B)</p> Signup and view all the answers

What is the term for the fluctuation of variables around a set point?

<p>Homeostasis (C)</p> Signup and view all the answers

In which level of organization do one or more tissues function together as a distinct entity?

<p>Organ Level (D)</p> Signup and view all the answers

Which directional term indicates a location toward the midline of the body?

<p>Medial (C)</p> Signup and view all the answers

What is the relationship of metabolism to the characteristics of life?

<p>It encompasses all chemical reactions. (B)</p> Signup and view all the answers

Which descriptive term refers to structures examined without the aid of a microscope?

<p>Macroscopic Anatomy (D)</p> Signup and view all the answers

Which of the following describes a positive feedback mechanism?

<p>Labor contractions during childbirth (A)</p> Signup and view all the answers

In anatomical terms, what does 'prone' refer to?

<p>Lying face down (D)</p> Signup and view all the answers

Which organ system is primarily associated with the heart and blood vessels?

<p>Cardiovascular System (D)</p> Signup and view all the answers

Which of the following represents a vital role of morphogenesis during development?

<p>Defining the shape and structure of tissues (C)</p> Signup and view all the answers

What does 'distal' refer to in terms of directional terms?

<p>Farther from the point of attachment (B)</p> Signup and view all the answers

What is the primary role of fibrinogen in the blood?

<p>Facilitating blood clotting (A)</p> Signup and view all the answers

What is one of the key functions of erythropoiesis in the circulatory system?

<p>Formation of red blood cells (A)</p> Signup and view all the answers

Which component of blood primarily affects the Rh factor in blood groups?

<p>Red blood cells (D)</p> Signup and view all the answers

Which waste product is a breakdown product of hemoglobin metabolism?

<p>Bilirubin (C)</p> Signup and view all the answers

What is a potential consequence of improper blood transfusion related to blood typing?

<p>Formation of antibodies (C)</p> Signup and view all the answers

Which of the following statements accurately describes a component of hemoglobin?

<p>Hemoglobin is comprised of four globin molecules and four heme molecules. (D)</p> Signup and view all the answers

Which of the following best describes the flow of erythropoiesis?

<p>Stem cells → proerythroblasts → early erythroblasts → reticulocytes → erythrocytes. (B)</p> Signup and view all the answers

What role do bicarbonate ions play in blood gas transport?

<p>They account for the majority of carbon dioxide transport in blood. (B)</p> Signup and view all the answers

Which factor increases the absorption of iron in the body?

<p>Vitamin C. (D)</p> Signup and view all the answers

Which type of blood cell is primarily derived from myeloblasts?

<p>Basophils. (D)</p> Signup and view all the answers

What is the primary function of carbonic anhydrase in red blood cells?

<p>Facilitating the conversion of carbon dioxide to bicarbonate ions. (D)</p> Signup and view all the answers

In which stage do proerythroblasts become reticulocytes during erythropoiesis?

<p>After the late erythroblast stage. (A)</p> Signup and view all the answers

What is the primary function of erythropoietin in the body?

<p>Promotes red blood cell production (D)</p> Signup and view all the answers

Why can Type O blood be considered a universal donor despite potentially causing transfusion reactions?

<p>It lacks A and B antigens (B)</p> Signup and view all the answers

What triggers the maternal immune response in Rh hemolytic disease of the newborn (HDN)?

<p>Crossing of Rh positive fetal antigens into maternal circulation (C)</p> Signup and view all the answers

What role do platelets play in the hemostatic process?

<p>They aid in the formation of platelet plugs (C)</p> Signup and view all the answers

What can be a consequence of the secondary immune response during an Rh positive pregnancy in an Rh negative mother?

<p>Development of antibodies that can destroy fetal red blood cells (B)</p> Signup and view all the answers

What happens to red blood cells during hemoglobin breakdown?

<p>Hemoglobin is converted into bilirubin (D)</p> Signup and view all the answers

What defines the Rh blood group?

<p>Presence or absence of Rh antigens on RBC surface (D)</p> Signup and view all the answers

Why might an introduction of fluid other than blood be referred to as an infusion?

<p>It does not involve blood components (D)</p> Signup and view all the answers

Which physiological reaction occurs when blood grouping antigens react with corresponding antibodies?

<p>Hemolysis or agglutination (D)</p> Signup and view all the answers

What is the primary role of DNA in cells?

<p>Encoding genetic instructions for protein synthesis (A)</p> Signup and view all the answers

Which component of nucleotides distinguishes DNA from RNA?

<p>Five-carbon sugar (A)</p> Signup and view all the answers

What is one reason cells utilize RNA as an intermediate between DNA and proteins?

<p>DNA can remain protected from cytoplasmic conditions (B)</p> Signup and view all the answers

Which of the following nitrogenous bases is found only in RNA?

<p>Uracil (C)</p> Signup and view all the answers

What is the significance of having multiple copies of RNA from one DNA molecule?

<p>It amplifies gene expression potential (B)</p> Signup and view all the answers

What role do purines play in nucleic acids?

<p>They are one type of nitrogenous base (B)</p> Signup and view all the answers

How does the structure of a nucleotide contribute to its function?

<p>Nitrogenous bases allow complementary pairing (B)</p> Signup and view all the answers

Which of the following statements about nucleic acid polymers is incorrect?

<p>RNA and DNA are both single-stranded. (A)</p> Signup and view all the answers

What allows for the regulation of gene expression in nucleic acids?

<p>The presence of multiple RNA copies (A)</p> Signup and view all the answers

Why is it important for DNA to remain separate from the cytoplasm?

<p>To maintain the purity of genetic material (C)</p> Signup and view all the answers

What is the role of RNA polymerase in the transcription process?

<p>It determines the correct DNA strand to use for mRNA synthesis. (B)</p> Signup and view all the answers

Which of the following statements about DNA structure is true?

<p>DNA helices are wrapped around proteins to form nucleosomes. (A)</p> Signup and view all the answers

How many chromosomes does a typical human cell contain?

<p>46 (C)</p> Signup and view all the answers

Which base is found in RNA but not in DNA?

<p>Uracil (D)</p> Signup and view all the answers

What occurs when a gene undergoes mutation?

<p>It may lead to the formation of a different protein. (C)</p> Signup and view all the answers

What is the primary function of messenger RNA (mRNA)?

<p>To serve as a template for protein synthesis. (D)</p> Signup and view all the answers

In the context of DNA, what is meant by 'gene loci'?

<p>The specific position of a gene on a chromosome. (B)</p> Signup and view all the answers

Which of the following processes involves DNA serving as a template?

<p>Transcription (A)</p> Signup and view all the answers

What is the primary characteristic of purines?

<p>They pair with pyrimidines in DNA. (A)</p> Signup and view all the answers

What difference distinguishes ribosomal RNA (rRNA) from other types of RNA?

<p>It forms part of the ribosomal structure. (C)</p> Signup and view all the answers

Which feature of pseudostratified epithelium distinguishes it from other epithelial types?

<p>Appears to have several layers of cells despite being a single layer (C)</p> Signup and view all the answers

What primary function is served by adipose connective tissue?

<p>Stores energy in the form of fat (B)</p> Signup and view all the answers

Which characteristic is unique to hyaline cartilage compared to other types of connective tissue?

<p>It is the most abundant type of cartilage (A)</p> Signup and view all the answers

What is the primary role of neurons within nervous tissue?

<p>To transmit impulses throughout the body (D)</p> Signup and view all the answers

What function do neuroglia serve in the nervous system?

<p>Protect and nurture neurons (B)</p> Signup and view all the answers

Which germ layer is primarily responsible for forming the epidermis and neural tissues?

<p>Ectoderm (B)</p> Signup and view all the answers

What is the main function of connective tissue?

<p>To connect, bind, and support structures (B)</p> Signup and view all the answers

Which type of tissue is primarily responsible for movement and locomotion?

<p>Muscle Tissue (C)</p> Signup and view all the answers

Which of the following is NOT a function of epithelial tissue?

<p>Generating nerve impulses (D)</p> Signup and view all the answers

Which primary tissue provides insulation and support to tissues and organs?

<p>Connective Tissue (D)</p> Signup and view all the answers

What is the main role of nervous tissue in the body?

<p>To control body functions and transmit signals (A)</p> Signup and view all the answers

What describes the primary function of serous fluid secreted by epithelial tissue?

<p>To lubricate structures within body cavities (B)</p> Signup and view all the answers

What type of epithelial tissue is characterized by being one cell thick and lining blood vessels and body cavities?

<p>Simple Squamous Epithelium (C)</p> Signup and view all the answers

Which type of connective tissue is primarily responsible for providing structural support and can be found in areas such as the nose and trachea?

<p>Hyaline Cartilage (C)</p> Signup and view all the answers

Which type of epithelium is specifically adapted for secretion and absorption in organs such as the kidneys?

<p>Simple Cuboidal Epithelium (D)</p> Signup and view all the answers

Which type of muscle tissue is characterized by involuntary control and is found in the walls of internal organs?

<p>Smooth Muscle (A)</p> Signup and view all the answers

Which of the following cell types is primarily responsible for conducting electrical impulses in the nervous system?

<p>Neurons (D)</p> Signup and view all the answers

What type of epithelium would you find lining the digestive tract, facilitating both absorption and secretion?

<p>Simple Columnar Epithelium (A)</p> Signup and view all the answers

What is the main distinguishing feature of stratified epithelium compared to simple epithelium?

<p>It consists of multiple layers of cells. (C)</p> Signup and view all the answers

What shape is typical of cuboidal epithelial cells, and where are they commonly found?

<p>Cube-shaped and found in ducts like the kidneys. (A)</p> Signup and view all the answers

Which type of connective tissue is specialized for energy storage and insulation?

<p>Adipose Tissue (D)</p> Signup and view all the answers

Which epithelial tissue type provides protection and is often found on the outer layer of the skin?

<p>Stratified Squamous Epithelium (C)</p> Signup and view all the answers

What are proteins primarily constructed from?

<p>Chains of amino acids (A)</p> Signup and view all the answers

Which type of protein facilitates specific chemical reactions in the body?

<p>Enzymes (B)</p> Signup and view all the answers

Which of the following amino acids characteristic features is shared among all amino acids?

<p>Central carbon atom bonded to NH2 and COOH (B)</p> Signup and view all the answers

What is the primary function of immunoglobulins within the context of proteins?

<p>Defense against foreign proteins (C)</p> Signup and view all the answers

Which class of protein primarily provides structural support to cells and tissues?

<p>Structural proteins (C)</p> Signup and view all the answers

How many amino acids are utilized to construct proteins in biological systems?

<p>21 (C)</p> Signup and view all the answers

What is NOT a function performed by proteins in cellular processes?

<p>Energy storage (D)</p> Signup and view all the answers

Which of the following proteins is involved in muscle contraction?

<p>Actin (A)</p> Signup and view all the answers

Taking into account their biological roles, what function do transport proteins serve?

<p>Transport small molecules and ions (B)</p> Signup and view all the answers

What is the largest known protein, known for its role in muscle structure?

<p>Titin (D)</p> Signup and view all the answers

What determines the shape of a protein?

<p>The sequence of nucleotide bases in the gene (D)</p> Signup and view all the answers

Which of the following best describes the primary structure of a protein?

<p>The linear sequence of amino acids (B)</p> Signup and view all the answers

Which level of protein structure involves the interaction of R-groups?

<p>Tertiary structure (D)</p> Signup and view all the answers

What happens to a protein when it is denatured?

<p>Its three-dimensional structure is disrupted (A)</p> Signup and view all the answers

Which of the following factors does NOT typically lead to protein denaturation?

<p>Hydrogen bond formation (C)</p> Signup and view all the answers

Polypeptides are referred to as proteins when they consist of how many amino acids?

<p>50 or more (D)</p> Signup and view all the answers

Which of the following statements regarding protein structure is false?

<p>Tertiary structure is determined solely by the primary structure. (A)</p> Signup and view all the answers

Which type of bond is primarily responsible for holding the secondary structure together?

<p>Hydrogen bonds (B)</p> Signup and view all the answers

In the context of protein folding, spontaneous folding is typically driven by what?

<p>The energetic stability of the folded form (A)</p> Signup and view all the answers

What kind of protein structure exists when a protein contains more than one polypeptide chain?

<p>Quaternary structure (A)</p> Signup and view all the answers

What is a common characteristic of Turner syndrome?

<p>Missing one X chromosome (B)</p> Signup and view all the answers

Which of the following conditions is associated with a male having an XXY chromosome pattern?

<p>Klinefelter syndrome (D)</p> Signup and view all the answers

Which trisomy condition is specifically linked to the 21st chromosome?

<p>Down syndrome (B)</p> Signup and view all the answers

What is a typical outcome for monosomic human zygotes missing any one copy of an autosome?

<p>Invariably fail to develop (D)</p> Signup and view all the answers

What is a common effect of Triple-X syndrome?

<p>Normal development in most cases (D)</p> Signup and view all the answers

What is the primary function of a gene?

<p>To influence hereditary traits in an individual (D)</p> Signup and view all the answers

Which autosome condition is associated with a risk of shorter lifespan due to severe organ system issues?

<p>Edward syndrome (C)</p> Signup and view all the answers

Which of the following correctly describes homologous chromosomes?

<p>Chromosomes with the same genetic sequence in the same locations (A)</p> Signup and view all the answers

Which characteristic is often observed in males with Jacob syndrome?

<p>Higher average height (D)</p> Signup and view all the answers

What is the main purpose of meiosis in the reproductive process?

<p>To shuffle genetic information and reduce the chromosome number (B)</p> Signup and view all the answers

What type of chromosomal abnormality does trisomy refer to?

<p>Presence of three copies of a chromosome (C)</p> Signup and view all the answers

What does the term 'locus' refer to in genetics?

<p>The location of a gene on a chromosome (A)</p> Signup and view all the answers

During which phase of mitosis do chromosomes become distinct?

<p>Metaphase (A)</p> Signup and view all the answers

How many daughter cells are produced at the end of meiosis?

<p>4 daughter cells (B)</p> Signup and view all the answers

What happens during the crossover phase of meiosis?

<p>Homologous chromosomes exchange genetic material (D)</p> Signup and view all the answers

Which type of cell division results in cells with the same DNA content as the parent cell?

<p>Mitosis (C)</p> Signup and view all the answers

Which of the following statements about meiosis is true?

<p>Meiosis includes two divisions leading to haploid cells (B)</p> Signup and view all the answers

What is the haploid number represented by the letter 'n' in human cells?

<p>23 distinct types of chromosomes (B)</p> Signup and view all the answers

Which phase follows prophase during mitosis?

<p>Metaphase (D)</p> Signup and view all the answers

What is nondisjunction during meiosis?

<p>When homologous chromosomes fail to separate correctly (D)</p> Signup and view all the answers

What type of chromosomes undergo nondisjunction?

<p>Both homologous chromosomes of a pair (A)</p> Signup and view all the answers

Which type of cell division occurs specifically in germ cells?

<p>Meiosis (A)</p> Signup and view all the answers

In which phase of meiosis is genetic material exchanged between chromatids?

<p>Meiosis I during prophase (A)</p> Signup and view all the answers

Which statement best describes the outcome of meiosis in relation to genetic diversity?

<p>Genetic information is shuffled, promoting diversity (D)</p> Signup and view all the answers

What is the primary purpose of meiosis?

<p>To shuffle genetic information and halve the chromosome number (A)</p> Signup and view all the answers

During which phase of meiosis do chromosomes exchange genetic material?

<p>Meiosis I (A)</p> Signup and view all the answers

What distinguishes haploid cells from diploid cells in meiosis?

<p>Haploid cells have one set of chromosomes (A)</p> Signup and view all the answers

What is the function of alleles in genetics?

<p>They influence one or more hereditary traits. (C)</p> Signup and view all the answers

What is a possible consequence of nondisjunction during meiosis?

<p>A gamete with two copies of a chromosome (A)</p> Signup and view all the answers

What describes homologous chromosomes?

<p>A pair of chromosomes that are similar in length and gene sequence. (C)</p> Signup and view all the answers

What is the primary outcome of mitosis?

<p>The production of two identical daughter cells. (D)</p> Signup and view all the answers

Which of the following describes the chromosome number in a haploid cell?

<p>23 chromosomes (C)</p> Signup and view all the answers

Which term represents the number of distinct types of chromosomes in a given cell?

<p>Haploid number. (A)</p> Signup and view all the answers

Which type of cells undergo meiosis?

<p>Germline cells (D)</p> Signup and view all the answers

What occurs during the anaphase of mitosis?

<p>Sister chromatids are pulled apart. (D)</p> Signup and view all the answers

What is the result of fertilization in terms of chromosome number?

<p>Restoration of the diploid chromosome number (B)</p> Signup and view all the answers

What is the total number of chromosomes present in a normal human karyotype?

<p>46 chromosomes. (B)</p> Signup and view all the answers

What is the primary characteristic of Turner syndrome?

<p>Missing one X chromosome (C)</p> Signup and view all the answers

Which process occurs exclusively in germ cells?

<p>Meiosis. (A)</p> Signup and view all the answers

Which condition is typically associated with males and an extra X chromosome?

<p>Klinefelter syndrome (C)</p> Signup and view all the answers

What are sister chromatids?

<p>Identical copies of a chromosome connected at a centromere. (C)</p> Signup and view all the answers

What is a common feature of individuals with Down syndrome?

<p>They have three copies of chromosome 21. (B)</p> Signup and view all the answers

What is the outcome for monosomic human zygotes that are missing an autosome?

<p>They invariably fail to develop to birth. (B)</p> Signup and view all the answers

What does Edward syndrome, associated with trisomy 18, primarily affect?

<p>Nearly every organ system in the body (C)</p> Signup and view all the answers

What is a potential learning issue for individuals with Jacob syndrome?

<p>Speech and reading problems (B)</p> Signup and view all the answers

Which of the following is true about the Triple-X syndrome?

<p>Most individuals have no apparent abnormalities. (A)</p> Signup and view all the answers

How is aneuploidy defined in relation to chromosome number?

<p>Gain or loss of one or more chromosomes (C)</p> Signup and view all the answers

Flashcards

Cell Communication

Cells communicate by receiving signals.

Extracellular Receptors

Hydrophilic signaling molecules bind to receptors on the cell surface, since they can't pass the cell membrane.

Intracellular Receptors

Small molecules can diffuse through the cell membrane and bind to receptors inside the cell.

Diffusion

Particles move from high to low concentrations due to thermal energy.

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Osmosis

Movement of water through a semi-permeable membrane along a concentration gradient.

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Isotonic Solution

A solution with an equal concentration of solutes compared to another solution, like inside a cell.

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Hypertonic Solution

A solution with a higher concentration of solutes compared to another solution, like in a cell.

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Facilitated Diffusion

The movement of molecules across a membrane with the help of a transport protein, still following a concentration gradient.

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Ion

An atom or molecule with a net positive or negative charge due to gaining or losing electrons.

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Cation

A positively charged ion.

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Anion

A negatively charged ion.

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Electrolyte

A substance that dissolves in water to form ions that conduct electricity.

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Acid

A compound that donates hydrogen ions (H+).

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Base

A compound that accepts hydrogen ions (H+).

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Electrolyte Balance

The proper ratio of ions in bodily fluids, essential for different body functions.

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What is an electrolyte's role in nerve and muscle function?

Electrolytes create electrical signals that allow nerves to communicate and muscles to contract.

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What is an acid?

An acid is a substance that releases hydrogen ions (H+) in solution.

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What is a base?

A base is a substance that accepts hydrogen ions (H+) in solution.

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pH Scale

The pH scale measures the acidity or alkalinity (basicity) of a solution. It ranges from 0 to 14, with 0 being the most acidic, 14 being the most alkaline, and 7 being neutral.

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What is a salt?

A salt is a compound formed by the reaction of an acid and a base.

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Litmus Test

A simple test to determine if a substance is acidic or basic. Blue litmus paper turns red in an acid and red litmus paper turns blue in a base.

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Strong Acid

An acid that ionizes completely in solution, releasing almost all of its hydrogen ions.

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Weak Acid

An acid that ionizes only partially in solution, releasing a small amount of hydrogen ions.

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pH of Blood

The pH of human blood is tightly regulated within a narrow range, typically around 7.35 to 7.45, slightly alkaline.

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Anatomy

The study of the body's structure, examining its parts and how they are organized.

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Physiology

The study of how the body's parts work together, focusing on their functions.

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Gross Anatomy

The study of body structures visible to the naked eye, like organs and tissues.

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Microscopic Anatomy

The study of body structures requiring a microscope, like cells and tissues.

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Histology

The study of tissues, focusing on how different cells work together.

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Organ System

A group of organs working together to perform a specific function, like the digestive system.

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Metabolism

All the chemical reactions that occur within the body, breaking down and building molecules.

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Responsiveness

The ability to sense and react to changes in the environment, like adjusting to cold temperatures.

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Growth

An increase in size or number of cells in the body, like a child growing taller.

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Organization

The specific arrangement of the body's parts, ensuring each has a role to play.

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Development

The process of change in an organism over time, from its initial stage to its mature form. This includes growth, differentiation, and morphogenesis.

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Differentiation

The process by which a less specialized cell becomes more specialized, acquiring a specific structure and function. This is essential for the formation of tissues and organs.

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Morphogenesis

The process of shaping and forming an organism's tissues and organs into their proper three-dimensional structure. It involves cell movement, growth, and death.

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Homeostasis

The maintenance of a stable internal environment within an organism, despite external changes. This is crucial for survival and involves regulating variables like temperature, pH, and blood sugar.

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Set Point

The ideal normal value for a variable that is being regulated in the body. For example, the set point for body temperature is 98.6°F.

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Negative Feedback

A mechanism that counteracts changes in a variable to maintain homeostasis. When a variable deviates from its set point, the response is to bring it back within the normal range.

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Positive Feedback

A mechanism that amplifies changes in a variable, leading to a greater deviation from the starting point. Usually not beneficial for normal homeostasis but important in specific scenarios like childbirth.

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Anatomical Position

A standardized reference position used to describe body structures. The body is standing erect, with feet together, palms facing forward, and head facing straight ahead.

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Superior (Cephalic)

Situated above or higher than another structure, closer to the head. Example: The head is superior to the chest.

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Inferior (Caudal)

Situated below or lower than another structure, closer to the tail. Example: The legs are inferior to the hips.

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Blood Composition

Blood is made up of two main components: plasma (the liquid part) and formed elements (cells and cell fragments).

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Plasma Functions

Plasma plays a crucial role in transporting substances throughout the body, regulating pH and osmosis, and maintaining body temperature.

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What are formed elements?

Formed elements are the cellular components of blood, including red blood cells (erythrocytes), white blood cells (leukocytes), and platelets (thrombocytes).

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Red Blood Cells

Red blood cells, also called erythrocytes, are biconcave discs that lack a nucleus and contain hemoglobin. They are responsible for oxygen and carbon dioxide transport.

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White Blood Cells

White blood cells, also called leukocytes, are involved in the body's immune defense. They come in different types: granulocytes and agranulocytes.

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Hematopoiesis

The process of blood cell production, starting from stem cells.

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Stem Cells

Undifferentiated cells that can develop into any type of blood cell, like a blank slate for blood.

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Red Blood Cell Function

Primarily responsible for transporting oxygen from the lungs to tissues and carbon dioxide from tissues back to the lungs.

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Hemoglobin

A protein inside red blood cells that binds to oxygen and transports it throughout the body. It also plays a role in carbon dioxide transport.

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Types of Hemoglobin

There are different types of hemoglobin: embryonic, fetal, and adult. Each has a different affinity for oxygen.

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Erythropoiesis

The process of red blood cell production, starting from stem cells and progressing through various stages.

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Red Blood Cell Life Cycle

Red blood cells live for approximately 120 days and are then recycled. The process involves various stages from stem cells to mature red blood cells.

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Transfusion

The transfer of blood or blood components from one individual to another.

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Antibody

A protein produced by the immune system that binds to specific antigens, leading to their inactivation or destruction.

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Agglutination

The clumping together of red blood cells due to the reaction between antibodies and antigens.

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ABO Blood Group

A blood grouping system based on the presence or absence of two antigens (A and B) and their corresponding antibodies on red blood cells.

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Hemolytic Disease of the Newborn (HDN)

A condition where antibodies from a Rh negative mother attack the red blood cells of an Rh positive fetus during pregnancy or delivery.

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Platelet

Small, cell fragments that play a crucial role in hemostasis (stopping bleeding) by forming platelet plugs and promoting blood clotting.

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What is DNA?

DNA is the hereditary material that determines our traits. It's passed down from parents to children.

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Where is DNA located?

DNA is found within the nucleus of every cell.

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How much DNA is in a cell?

Each cell contains about 3 billion bases of DNA, coiled up tightly.

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What are chromosomes?

Chromosomes are structures made of DNA that contain genes. Humans have 46 chromosomes, 23 from each parent

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What are genes?

Genes are segments of DNA that code for specific proteins, which perform various functions in the body.

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What are the building blocks of DNA?

DNA is made up of sugar (deoxyribose), phosphate, and four nitrogenous bases: adenine (A), guanine (G), cytosine (C), and thymine (T).

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What are the base pairing rules in DNA?

Adenine (A) always pairs with thymine (T), and guanine (G) always pairs with cytosine (C).

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What is DNA replication?

DNA replication is the process of making an exact copy of DNA before cell division. This ensures each new cell receives a complete set of genetic instructions.

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What is transcription?

Transcription is the process of making a copy of DNA called RNA, which then carries the genetic information to the ribosomes for protein production.

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What are the types of RNA?

There are 3 main types of RNA: messenger RNA (mRNA), transfer RNA (tRNA), and ribosomal RNA (rRNA). They work together to translate genetic information into proteins.

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Nucleic Acids: What are they?

Nucleic acids are polymers made of nucleotides, serving as the cell's information storage devices. They are responsible for storing and transmitting genetic information.

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DNA vs. RNA

DNA (deoxyribonucleic acid) is the primary genetic material, while RNA (ribonucleic acid) is involved in protein synthesis. DNA stores the genetic code, while RNA helps translate it into proteins.

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Why is DNA essential?

DNA contains the genetic instructions for building and maintaining an organism. It directs the synthesis of proteins, which are the building blocks and workhorses of the body.

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Central Dogma of Genetics

The central dogma describes the flow of genetic information from DNA to RNA to protein. DNA is transcribed into RNA, and RNA is translated into protein.

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What is a Nucleotide?

A nucleotide is the basic building block of nucleic acids. It consists of a sugar molecule, a phosphate group, and a nitrogenous base.

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Purines and Pyrimidines

These are the two groups of nitrogenous bases found in nucleotides. Purines have a double-ring structure (adenine, guanine), while pyrimidines have a single-ring structure (cytosine, thymine, uracil).

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Why have RNA?

RNA acts as an intermediary between DNA and proteins. It allows DNA to remain protected in the nucleus while RNA acts as a messenger, carrying information to the ribosomes for protein synthesis.

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RNA Amplification

Multiple copies of RNA can be made from a single DNA template, amplifying gene information. This allows for efficient protein production without compromising the DNA.

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Gene Expression Regulation

The flow of genetic information can be controlled at each step from DNA to protein, enabling fine-tuning of gene expression. This allows cells to adapt to different environments.

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Importance of Nucleic Acid Structure

The specific sequence of nucleotides in DNA and RNA determines the genetic code, which dictates the order of amino acids in proteins. This structure is crucial for accurate protein synthesis and ultimately for cell function.

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Pseudostratified Epithelium

A single layer of cells that appears to have multiple layers due to the varying heights of the cells and their nuclei placement. It's often found lining the respiratory tract and parts of the male reproductive system.

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Adipose Connective Tissue

A type of connective tissue made up of fat cells (adipocytes) that store energy in the form of triglycerides. It also insulates the body and cushions organs.

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Bone Connective Tissue

A hard and rigid connective tissue made up of collagen fibers and calcium phosphate. It provides support and protection for the body, stores minerals, and produces blood cells.

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Hyaline Cartilage

A type of cartilage that is smooth and glassy in appearance. It provides support while allowing flexibility, and is found in joints, respiratory passages, and the nose.

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Neurons

Specialized cells in the nervous system that transmit electrical signals throughout the body. They have long processes called axons and dendrites, and a cell body containing the nucleus.

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Epithelial Tissue

A sheet of tightly packed cells covering body surfaces, lining body cavities, and forming glands. It acts as a barrier, filter, and secretory surface.

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What are Tissues?

Tissues are groups of similar cells that work together to perform a specific function. There are approximately 200 different types of cells in the human body.

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Totipotent Cell

A totipotent cell is a cell that has the potential to develop into any type of cell in the body. A fertilized egg is totipotent.

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Squamous Epithelium

Epithelium composed of thin, flat cells. It's found in areas where diffusion or filtration is important, like lining blood vessels and alveoli.

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Cuboidal Epithelium

Epithelium made up of cube-shaped cells. It's involved in secretion and absorption, found in glands and kidney tubules.

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Germ Layers

Germ layers are three basic layers of cells that form during embryonic development. These layers give rise to all the different tissues in the body.

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Columnar Epithelium

Epithelium with tall, column-shaped cells. It's involved in absorption and secretion, found in the lining of the digestive tract.

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Ectoderm

The outer layer of the three germ layers. It forms the epidermis, nervous tissues, and some skeletal and connective tissues in the head.

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Connective Tissue

Tissue that supports and connects other tissues and organs. It provides structure, protection, and insulation.

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Mesoderm

The middle layer of the three germ layers. It forms most muscles, skeletal tissues, the urogenital system, heart, and blood vessels.

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Adipose Tissue

A type of connective tissue that stores fat. It insulates the body, provides cushioning, and stores energy.

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Endoderm

The inner layer of the three germ layers. It forms the lining of the digestive and respiratory systems and associated organs.

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Bone Tissue

A type of connective tissue that forms the skeleton. It provides support, protection, and allows movement.

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Four Basic Tissue Types

The four basic kinds of tissues in the body are epithelial, connective, muscle, and nervous tissue.

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Muscle Tissue

Tissue composed of specialized cells capable of contraction. It allows movement, maintains posture, and generates heat.

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Nervous Tissue

Tissue composed of neurons and neuroglia. It transmits information throughout the body, controlling and coordinating functions.

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Polypeptide

A long chain of amino acids linked together by peptide bonds. It is a primary component of proteins.

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Primary Structure

The linear sequence of amino acids in a protein. It is like the alphabet of the protein.

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Secondary Structure

The local folding of the polypeptide chain into specific shapes, due to hydrogen bonding between amino acids. Common forms include alpha helices and beta sheets.

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Tertiary Structure

The overall three-dimensional shape of a protein molecule, resulting from interactions between R-groups of the amino acids. It determines the protein's function.

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Quaternary Structure

The arrangement of multiple polypeptide chains (subunits) to form a functional protein. It is found in some proteins, but not all.

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Protein Denaturation

The unfolding of a protein's structure, disrupting its function. This can be caused by factors like heat, pH changes, or chemicals.

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Hydrogen Bonds

Weak bonds that form between partially positive and partially negative atoms, like between amino acids in a protein.

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R-groups

The variable side chains of amino acids, which give them their unique chemical properties. They contribute to protein structure and function.

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Hydrophobic Interactions

Interactions between nonpolar amino acids that tend to cluster together, avoiding water. These interactions help drive protein folding.

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Function of a Protein

The specific biological role a protein performs, which is determined by its three-dimensional shape.

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What are proteins made from?

Proteins are made from chains of amino acids, linked together like beads on a string. These chains are called polypeptides.

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What are amino acids?

Amino acids are the building blocks of proteins. They have a central carbon atom connected to four groups: a carboxyl group (COOH), an amino group (NH2), a hydrogen atom (H), and a variable side chain (R).

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What is the role of proteins in cells?

Proteins are involved in many essential functions in cells, including speeding up chemical reactions (enzymes), fighting infections (defense), moving substances (transport), providing structural support (support), allowing movement (motion), and regulating processes (regulation).

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What is a polypeptide?

A polypeptide is a chain of amino acids linked together by peptide bonds. It's a shorter version of a protein.

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What is a peptide bond?

A peptide bond is a special chemical link that connects amino acids together in a polypeptide. It's formed between the carboxyl group of one amino acid and the amino group of the next.

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What is the difference between polypeptides and proteins?

Polypeptides are short chains of amino acids, while proteins are longer, folded chains of amino acids. A single protein can be made of one or more polypeptide chains.

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What are enzymes?

Enzymes are proteins that act as biological catalysts, speeding up chemical reactions in cells without being changed themselves. They have specific shapes that allow them to bind to specific molecules.

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What are antibodies?

Antibodies are proteins produced by the immune system that bind to specific foreign molecules (antigens) and help to destroy them.

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What is a side chain (R-group)?

The R-group is the unique part of an amino acid. It varies from one amino acid to the next and gives each amino acid its specific properties.

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What are alleles?

Alleles are different versions of the same gene. Each individual inherits two alleles for each gene, one from each parent.

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What is a locus?

A locus is the specific location of a gene on a chromosome. It's like a 'street address' for a gene.

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What are homologous chromosomes?

Homologous chromosomes are a pair of chromosomes that have the same gene sequences at the same locations. They come from the mother and father.

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What is a karyotype?

A karyotype is a complete set of chromosomes arranged in order of size and shape. It's like a photo of all the chromosomes in a cell.

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What is the haploid number?

The haploid number (n) is the number of distinct types of chromosomes in a cell. It's half the number of chromosomes in a diploid cell.

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What are the two types of cell division?

The two types of cell division are mitosis and meiosis.

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What does mitosis produce?

Mitosis produces two identical daughter cells, each with the same number of chromosomes as the parent cell.

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What is meiosis for?

Meiosis is a type of cell division that halves the number of chromosomes in a cell, producing gametes (sperm and egg) with only half the genetic material of the parent cell.

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What happens during meiosis I?

In meiosis I, homologous chromosomes pair up and exchange genetic material through a process called crossing over. This creates new combinations of genes on each chromosome.

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What happens during meiosis II?

Meiosis II is similar to mitosis, where sister chromatids separate, resulting in four daughter cells, each with half the number of chromosomes as the original cell.

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Haploid vs Diploid

Haploid cells have only one set of chromosomes (n), like sperm and egg. Diploid cells have two sets (2n), like most cells in the body.

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What is fertilization?

Fertilization is the fusion of a sperm and an egg cell, restoring the diploid number of chromosomes and creating a zygote, the first cell of a new individual.

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Nondisjunction

Nondisjunction is an error in meiosis where chromosomes fail to separate properly, resulting in gametes with an abnormal number of chromosomes.

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What are the consequences of nondisjunction?

Nondisjunction can lead to genetic disorders such as Down syndrome (trisomy 21) and Turner syndrome (XO) where individuals have an extra or missing chromosome.

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How does meiosis contribute to genetic diversity?

Meiosis creates genetic diversity through crossing over, which shuffles genes on chromosomes, and independent assortment, which randomly separates chromosomes into gametes.

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Turner Syndrome

A genetic condition in females caused by the partial or complete absence of an X chromosome, resulting in a XO karyotype. It's characterized by short stature, lack of puberty, normal intelligence, and a higher risk of kidney and heart problems.

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Klinefelter Syndrome

A genetic condition in males with an extra X chromosome, resulting in an XXY karyotype. It's characterized by underdeveloped sexual characteristics, sterility, possible breast development, language impairment, and may affect gender identity.

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Triple-X Syndrome

A genetic condition in females with an extra or multiple X chromosomes, resulting in XXX or XXXX karyotype. Most individuals with this condition have no obvious abnormalities, but some may experience early menopause, learning delays, or language impairment.

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Jacob Syndrome

A genetic condition in males with an extra Y chromosome, resulting in an XYY karyotype. Individuals with this condition often have above-average height and may experience speech and reading difficulties.

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Euploid

An individual with the normal number of chromosomes for their species, with 22 pairs of autosomes and one pair of sex chromosomes in humans.

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Aneuploid

An individual with an abnormal number of chromosomes, including monosomy (loss of one chromosome) or trisomy (gain of an extraneous chromosome).

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Trisomy

The presence of three copies of a particular chromosome, instead of the usual two.

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Down Syndrome

A genetic disorder caused by trisomy 21, characterized by distinct physical features, learning difficulties, and a higher risk of health problems.

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What is Meiosis?

Meiosis is a type of cell division that reduces the number of chromosomes in a cell by half, creating gametes (sperm and egg cells) with only 23 chromosomes each.

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What is the main function of Meiosis?

The purpose of meiosis is to ensure that when an egg and sperm cell combine during fertilization, the resulting embryo will inherit the correct number of chromosomes and a unique combination of genetic information from each parent.

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What is Nondisjunction?

Nondisjunction is an error during meiosis where homologous chromosomes fail to separate properly, resulting in gametes with an abnormal number of chromosomes. This can lead to genetic disorders.

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What is Haploid?

Haploid refers to cells that contain only one set of chromosomes. Gametes (sperm and egg cells) are haploid cells.

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What is Diploid?

Diploid refers to cells that contain two sets of chromosomes, one from each parent. Most cells in our body are diploid.

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Compare Mitosis and Meiosis

Mitosis produces two daughter cells that are identical to the parent cell, while meiosis produces four daughter cells that are genetically different from the parent cell. Mitosis is for growth and repair, while meiosis is for sexual reproduction.

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Study Notes

Cell Biology - Cell Communication

  • Signaling molecules can be hydrophilic or hydrophobic
  • Hydrophilic molecules cannot cross the plasma membrane, binding to cell-surface receptors
  • Small hydrophobic molecules diffuse across the membrane, binding to intracellular receptors

Cell Communication - Types

  • Contact-dependent: Signaling cell and target cell have direct contact, with membrane-bound signaling molecules.
  • Paracrine: Signalling cells release local mediators that act on nearby target cells
  • Synaptic: Neurotransmitters released from neurons affect target cells at synapses
  • Endocrine: Endocrine cells release hormones into the bloodstream to act on distant target cells

Cell Membrane Structure

  • Composed of a phospholipid bilayer
  • Contains various proteins:
    • Integral proteins, spanning the membrane
    • Peripheral proteins, attached to the membrane surface
    • Channel proteins
    • Globular proteins
    • Glycoproteins
    • Glycolipids
    • Cholesterol

Role of Water in Cell Biology

  • Water serves as an excellent solvent for a wide range of substances
  • Water's high surface tension and capillary action facilitate processes
  • Water regulates temperature through its high heat capacity and heat of vaporization
  • Water is neutral, neither acidic nor alkaline

Processes of Substance Movement

  • Diffusion: Movement of dissolved or suspended particles from high to low concentration due to thermal energy (heat)
  • Osmosis: Movement of water across a selectively permeable membrane from a high to low water concentration
  • Dialysis: Movement of solutes across a semipermeable membrane from a high to low solute concentration

Osmosis

  • Hypertonic: Solution with higher solute concentration than the cell. Water moves out of the cell, causing the cell to shrink.
  • Hypotonic: Solution with lower solute concentration than the cell. Water moves into the cell, causing the cell to swell.
  • Isotonic: Solution with equal solute concentration to the cell. No net movement of water.

Transport across the Plasma Membrane

  • Passive transport: Movement of substances across the membrane without energy input. Includes diffusion and facilitated diffusion
  • Facilitated transport: Movement of polar or charged substances with assistance of membrane proteins. This is a type of passive transport.
  • Active transport: Energy-dependent movement of substances across the membrane against their concentration gradient

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