Podcast
Questions and Answers
What is the primary function of microtubules in the cell?
What is the primary function of microtubules in the cell?
Which type of cytoskeletal structure is primarily responsible for resisting pulling forces on the cell?
Which type of cytoskeletal structure is primarily responsible for resisting pulling forces on the cell?
What distinguishes cilia from flagella?
What distinguishes cilia from flagella?
Which of the following correctly describes microvilli?
Which of the following correctly describes microvilli?
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Which of the following statements about cytosol and cytoplasm is correct?
Which of the following statements about cytosol and cytoplasm is correct?
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What percentage of the cell membrane is made up of carbohydrates?
What percentage of the cell membrane is made up of carbohydrates?
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Which type of proteins extend through the entire thickness of the cell membrane?
Which type of proteins extend through the entire thickness of the cell membrane?
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What is the primary function of the cell membrane's ion channels?
What is the primary function of the cell membrane's ion channels?
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What is the main role of ribosomal RNA synthesis in the nucleus?
What is the main role of ribosomal RNA synthesis in the nucleus?
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What do lipoproteins and glycoproteins represent in the cell membrane?
What do lipoproteins and glycoproteins represent in the cell membrane?
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Which structure inside the nucleus is primarily involved in storing DNA?
Which structure inside the nucleus is primarily involved in storing DNA?
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How does the cell membrane contribute to cellular communication?
How does the cell membrane contribute to cellular communication?
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What feature of the nucleus is essential for the control of cell function?
What feature of the nucleus is essential for the control of cell function?
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What is the primary structural and functional unit of life?
What is the primary structural and functional unit of life?
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Which statement correctly describes the plasma membrane?
Which statement correctly describes the plasma membrane?
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What characteristic feature of phospholipids allows them to form a bilayer in the plasma membrane?
What characteristic feature of phospholipids allows them to form a bilayer in the plasma membrane?
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What is the function of the membrane proteins in the plasma membrane?
What is the function of the membrane proteins in the plasma membrane?
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Why is homeostasis important for the human body?
Why is homeostasis important for the human body?
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What describes the hydrophilic portion of phospholipids?
What describes the hydrophilic portion of phospholipids?
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Which component is NOT part of the lipid bilayer of the plasma membrane?
Which component is NOT part of the lipid bilayer of the plasma membrane?
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What does the Fluid Mosaic Model describe about the plasma membrane?
What does the Fluid Mosaic Model describe about the plasma membrane?
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What is the primary function of the mitochondria in the cell?
What is the primary function of the mitochondria in the cell?
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What is the composition of ribosomes within the cell?
What is the composition of ribosomes within the cell?
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Which organelle is primarily responsible for detoxifying drugs and synthesizing lipids?
Which organelle is primarily responsible for detoxifying drugs and synthesizing lipids?
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What structural components make up the cytoskeleton?
What structural components make up the cytoskeleton?
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How do lysosomes function within a cell?
How do lysosomes function within a cell?
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Study Notes
Cell and Cell Organelles
- The presentation is about cells and cell organelles.
- The presenter is Dr. Rasha Eldeeb, Associate Professor of Physiology, Gulf Medical University.
- The date of the presentation is September 3, 2024.
- Learning objectives include describing the general characteristics of cells, the structure of a typical cell, the structure of the plasma membrane (Fluid Mosaic Model), the function of membrane proteins, and the structure and function of different cell organelles.
What is Physiology?
- Physiology is the branch of biology that studies the functions and vital processes of living organisms.
- It explains the physical and chemical factors responsible for life's origin, development, and progression.
- Physiology includes subjects like cell biology, molecular chemistry, and biology.
- It also relates to factors like organs, populations/species, and ecosystems.
Why Do We Study Physiology?
- Physiology is studied to understand the physiologic principles of normal function in order to treat impairments.
- Physiology helps distinguish between the process and function of biological components.
- The function of components is determined by analyzing how components should work.
- Processes are about determining how something is done or works (e.g. respiration, blood flow, oxygen transport).
What You Should Know
- The human body is organized from cells to organs as integrated units.
- The human body needs a constant internal environment to function properly.
- Physiology deals with the mechanisms that maintain a stable internal environment despite changes in the external environment. This is known as homeostasis.
- Diagrams of atomic structures and cellular levels were shown.
The Cell
- Divided into prokaryotic and eukaryotic cells.
- Prokaryotic cells lack a nucleus and membrane-bound organelles.
- Eukaryotic cells contain a nucleus and membrane-bound organelles.
The Cell Membrane
- The cell membrane is a thin, semipermeable barrier between the cell and its surroundings.
- It consists of a lipid bilayer.
- Phospholipids form the base of the bilayer with a hydrophilic head and hydrophobic tail.
- Cholesterol is also present in the membrane.
- The hydrophilic heads face the water-based environment, while the hydrophobic tails face each other to create a hydrophobic interior to the membrane.
The Cell Membrane - Proteins
- Proteins (55%) are not a continuous layer like lipids, but instead exist as discrete units.
- Integral proteins extend through the whole membrane.
- Peripheral proteins are on a surface of the membrane, either inside or outside the cell.
- Functional proteins have different purposes such as receptors, channels, pumps, etc.
The Cell Membrane - Functions
- Regulating the passage of substances into and out of cells.
- Detecting chemical messengers at the cell surface.
- Linking adjacent cells via membrane junctions.
- Anchoring proteins (intracellular/extracellular) for force generation.
The Nucleus
- Usually the largest organelle, surrounded by a nuclear membrane with pores.
- Contains the cell's DNA in chromosomes.
- Controls cell function.
- The genes control cell characteristics.
What is inside the Nucleus?
- The genetic material (DNA) is found, organized as chromatin in non-dividing cells, and chromosomes in dividing cells.
- Chromatin is formed by DNA wrapped around proteins.
- Inside the nucleus is the nucleolus; responsible for ribosomal RNA synthesis.
The Mitochondria
- The size of a bacterium.
- Has a double membrane (smooth outer, inner with cristae).
- Contains DNA, mDNA, RNA, and ribosomes.
- Produces ATP (high-energy compound).
- The power-house of the cell
The Endoplasmic Reticulum
- A complex network of transport channels.
- Two types:
- Smooth (no ribosomes): detoxifies and produces lipids.
- Rough (with ribosomes): manufactures proteins.
The Ribosomes
- Consist of two subunits.
- The site of protein synthesis ("protein factory").
- Can be free-floating or attached to the ER.
The Golgi Apparatus
- Flattened sacs that modify, package, store, and transport materials out of the cell.
- Works with ribosomes and ER.
The Lysosome
- Membrane-bound organelle containing digestive enzymes.
- Digests food particles inside or outside the cell.
- Also called "suicide bags".
The Cytoskeleton
- The framework of the cell.
- Consists of three main components: microfilament, intermediate filament, and microtubules.
- They help maintain cell shape, support organelles, and regulate cell movement.
The Cytoskeleton – Microfilaments
- Attached to the cytoplasmic membrane for strength and to resist cell deformation.
- Tough proteins.
The Cytoskeleton – Microtubules
- Hollow tubes.
- Present in all cells (but not RBCs).
- Important in moving materials around the cells.
- Forms cilia and flagella.
The Cellular Extensions
- Extensions of the plasma membrane, such as:
- microvilli
- stereocilia
- cilia
- flagella
Cytosol vs Cytoplasm
- Cytosol: liquid portion of cytoplasm.
- Cytoplasm: all contents of the cell excluding the nucleus.
Learning Resources
- A list of suggested textbooks and websites to consult for further learning.
Disclaimer
- The presentation content is for educational use only within Gulf Medical University.
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Description
Explore the fascinating world of cells and their organelles with Dr. Rasha Eldeeb. This quiz covers key characteristics, structures, and functions of various cell components and the plasma membrane. Join us to enhance your understanding of physiology and cellular biology.