CDC STI Treatment Guidelines 2021
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What is the first-line treatment for adults and adolescents when M. genitalium is detected, assuming resistance testing is unavailable?

  • Moxifloxacin 400 mg 1x/day for 7 days
  • Azithromycin 1 gm orally in a single dose
  • Doxycycline 100 mg orally 2x/day for 7 days (correct)
  • Levofloxacin 500 mg orally 1x/day for 7 days

    • Which medication should be administered after doxycycline if moxifloxacin cannot be used for M. genitalium treatment?

  • Azithromycin 1 gm orally in a single dose (correct)
  • Azithromycin 500 mg orally 1x/day
  • Moxifloxacin 400 mg 1x/day for 7 days
  • Amoxicillin 500 mg orally 3x/day for 7 days

    • In pregnant individuals, what is the recommended treatment for M. genitalium?

  • Azithromycin 1 gm orally in a single dose (correct)
  • Azithromycin 500 mg orally 1x/day
  • Moxifloxacin 400 mg 1x/day
  • Doxycycline 100 mg orally 2x/day

    • For how long should doxycycline be administered to adults and adolescents in the treatment of M. genitalium?

    <p>7 days</p> Signup and view all the answers

    What should be the follow-up treatment after levofloxacin if M. genitalium is confirmed?

    <p>Azithromycin 1 gm orally in a single dose</p> Signup and view all the answers

    Which treatment is available for children with a confirmed M. genitalium infection?

    <p>Azithromycin 1 gm orally in a single dose</p> Signup and view all the answers

    What is the recommended dosage of azithromycin when it is used as the first treatment option?

    <p>1 gm orally in a single dose</p> Signup and view all the answers

    For individuals where moxifloxacin is not suitable after doxycycline, which alternative is typically suggested?

    <p>Azithromycin 1 gm orally on the first day, followed by 500 mg 1x/day</p> Signup and view all the answers

    What is the primary recommended regimen for treating Bacterial Vaginosis?

    <p>metronidazole 500 mg orally 2x/day for 7 days</p> Signup and view all the answers

    In the treatment of Lymphogranuloma Venereum, which of the following is considered an alternative regimen?

    <p>azithromycin 1 gm orally 1x/week for 3 weeks</p> Signup and view all the answers

    Which treatment option is appropriate for a patient with Nongonococcal Urethritis (NGU)?

    <p>azithromycin 500 mg orally in a single dose, THEN 250 mg 1x/day for 4 days</p> Signup and view all the answers

    What is a key aspect of STI treatment beyond pharmacological regimens?

    <p>Partner management</p> Signup and view all the answers

    What regimen is recommended for Cervicitis?

    <p>azithromycin 1 gm orally in a single dose</p> Signup and view all the answers

    For Persistent or Recurrent NGU, testing for which pathogen is recommended?

    <p>Mycoplasma genitalium</p> Signup and view all the answers

    Which alternative regimen can be used for Bacterial Vaginosis?

    <p>metronidazole gel 0.75%, one 5 gm applicator intravaginally at bedtime</p> Signup and view all the answers

    Which oral medication is a primary treatment option for Chlamydial Infections?

    <p>doxycycline 100 mg orally 2x/day for 7 days</p> Signup and view all the answers

    Which of the following is NOT an alternative regimen for treating Lymphogranuloma Venereum?

    <p>clindamycin cream 2%, one 5 gm applicator intravaginally</p> Signup and view all the answers

    Which is a key factor influencing the choice of therapeutic regimens in STI treatment?

    <p>Efficacy, cost, or convenience</p> Signup and view all the answers

    What is the recommended duration for administering doxycycline to adults and adolescents for M. genitalium treatment?

    <p>7 days</p> Signup and view all the answers

    Which medication is recommended for pregnant individuals with M. genitalium?

    <p>Azithromycin</p> Signup and view all the answers

    If moxifloxacin cannot be used, which medication is given after doxycycline for M. genitalium treatment?

    <p>Azithromycin</p> Signup and view all the answers

    In treatment administration for M. genitalium, what is the dosage of azithromycin given on the first day?

    <p>1 gm</p> Signup and view all the answers

    Which of the following is NOT a regimen for treating a confirmed M. genitalium infection?

    <p>Amoxicillin for 7 days</p> Signup and view all the answers

    How frequently is doxycycline administered to adults and adolescents during the 7-day treatment?

    <p>Twice a day</p> Signup and view all the answers

    What is the indicated follow-up treatment after levofloxacin in the M. genitalium treatment regimen?

    <p>Azithromycin</p> Signup and view all the answers

    What is the dosage of levofloxacin when treating M. genitalium in adults and adolescents?

    <p>500 mg once a day</p> Signup and view all the answers

    What is the primary recommended regimen for treating Bacterial Vaginosis?

    <p>metronidazole 500 mg orally 2x/day for 7 days</p> Signup and view all the answers

    Which of the following is an alternative regimen for treating Lymphogranuloma Venereum?

    <p>azithromycin 1 gm orally 1x/week for 3 weeks</p> Signup and view all the answers

    In the treatment of Nongonococcal Urethritis (NGU), which regimen is recommended?

    <p>azithromycin 1 gm orally in a single dose</p> Signup and view all the answers

    Which drug is not considered an alternative for Bacterial Vaginosis?

    <p>fluconazole 150 mg orally single dose</p> Signup and view all the answers

    What is a key component of STI treatment aside from pharmacological regimens?

    <p>Partner management</p> Signup and view all the answers

    Which alternative regimen is suggested for Cervicitis?

    <p>azithromycin 2 gm orally in a single dose</p> Signup and view all the answers

    For Persistent or Recurrent NGU, testing for which pathogen is advised?

    <p>Mycoplasma genitalium</p> Signup and view all the answers

    When treating Lymphogranuloma Venereum, how long should doxycycline be administered?

    <p>21 days</p> Signup and view all the answers

    What is the recommended dosage of azithromycin for treating Cervicitis?

    <p>1 gm orally in a single dose</p> Signup and view all the answers

    Which treatment should be considered in cases of substantial drug allergy for NGU?

    <p>tinidazole 2 gm orally 1x/day for 2 days</p> Signup and view all the answers

    Study Notes

    Overview of CDC STI Treatment Guidelines, 2021

    • Presents recommended therapeutic regimens for sexually transmitted infections (STIs) in a wall chart format.
    • Regimens are listed alphabetically unless prioritized by efficacy, cost, or convenience.
    • Recommended regimens should be primarily used, with alternatives considered only for significant drug allergies or contraindications.
    • Emphasizes the importance of partner management in STI treatment.

    • Bacterial Vaginosis:

      • Recommended: Metronidazole 500 mg orally, twice daily for 7 days.
      • Alternatives: Clindamycin 300 mg orally, twice daily for 7 days or various intravaginal options (metronidazole gel, clindamycin ovules, clindamycin cream).

    • Lymphogranuloma Venereum:

      • Recommended: Doxycycline 100 mg orally, twice daily for 21 days.
      • Alternatives: Azithromycin 1 gm orally, once a week for 3 weeks, or erythromycin base 500 mg orally, four times daily for 21 days.

    • Nongonococcal Urethritis (NGU):

      • Recommended: Doxycycline 100 mg orally, twice daily for 7 days.
      • Alternatives: Azithromycin 1 gm orally in a single dose, or tinidazole options (2 gm once daily for 2 days, or 1 gm once daily for 5 days).

    • Cervicitis:

      • Recommended: Doxycycline 100 mg orally, twice daily for 7 days.
      • Alternatives: Azithromycin 1 gm orally in a single dose.

    Chlamydial Infections

    • Adults and Adolescents:

      • Recommended: Doxycycline 100 mg orally, twice daily for 7 days.
      • Alternatives: Azithromycin 1 gm orally in a single dose or levofloxacin 500 mg orally, once daily for 7 days.

    • Pregnancy:

      • Recommended: Azithromycin 1 gm orally in a single dose.
      • Alternatives: Amoxicillin 500 mg orally, three times daily for 7 days.

    Persistent or Recurrent NGU

    • Testing for Mycoplasma genitalium is advised.
    • If M. genitalium is detected but resistance testing is unavailable:
      • Treatment follows an initial regimen of doxycycline, followed by moxifloxacin 400 mg, once daily for 7 days.

    Important Notes

    • A comprehensive guideline is accessible online at www.cdc.gov/std/treatment.
    • Partner management should be part of the treatment process, potentially involving health department cooperation.

    Overview of CDC STI Treatment Guidelines, 2021

    • Presents recommended therapeutic regimens for sexually transmitted infections (STIs) in a wall chart format.
    • Regimens are listed alphabetically unless prioritized by efficacy, cost, or convenience.
    • Recommended regimens should be primarily used, with alternatives considered only for significant drug allergies or contraindications.
    • Emphasizes the importance of partner management in STI treatment.

    • Bacterial Vaginosis:

      • Recommended: Metronidazole 500 mg orally, twice daily for 7 days.
      • Alternatives: Clindamycin 300 mg orally, twice daily for 7 days or various intravaginal options (metronidazole gel, clindamycin ovules, clindamycin cream).

    • Lymphogranuloma Venereum:

      • Recommended: Doxycycline 100 mg orally, twice daily for 21 days.
      • Alternatives: Azithromycin 1 gm orally, once a week for 3 weeks, or erythromycin base 500 mg orally, four times daily for 21 days.

    • Nongonococcal Urethritis (NGU):

      • Recommended: Doxycycline 100 mg orally, twice daily for 7 days.
      • Alternatives: Azithromycin 1 gm orally in a single dose, or tinidazole options (2 gm once daily for 2 days, or 1 gm once daily for 5 days).

    • Cervicitis:

      • Recommended: Doxycycline 100 mg orally, twice daily for 7 days.
      • Alternatives: Azithromycin 1 gm orally in a single dose.

    Chlamydial Infections

    • Adults and Adolescents:

      • Recommended: Doxycycline 100 mg orally, twice daily for 7 days.
      • Alternatives: Azithromycin 1 gm orally in a single dose or levofloxacin 500 mg orally, once daily for 7 days.

    • Pregnancy:

      • Recommended: Azithromycin 1 gm orally in a single dose.
      • Alternatives: Amoxicillin 500 mg orally, three times daily for 7 days.

    Persistent or Recurrent NGU

    • Testing for Mycoplasma genitalium is advised.
    • If M. genitalium is detected but resistance testing is unavailable:
      • Treatment follows an initial regimen of doxycycline, followed by moxifloxacin 400 mg, once daily for 7 days.

    Important Notes

    • A comprehensive guideline is accessible online at www.cdc.gov/std/treatment.
    • Partner management should be part of the treatment process, potentially involving health department cooperation.

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    Related Documents

    Summary of CDC STI Treatment Guidelines, 2021 PDF
    Summary of CDC STI Treatment Guidelines 2021 PDF

    Description

    This quiz covers the recommended therapeutic regimens for sexually transmitted infections (STIs) as outlined in the CDC's 2021 guidelines. It includes specific treatments for conditions like bacterial vaginosis and lymphogranuloma venereum. Understanding these regimens is crucial for effective STI management and partner care.

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