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Questions and Answers
What is the first-line treatment for adults and adolescents when M. genitalium is detected, assuming resistance testing is unavailable?
What is the first-line treatment for adults and adolescents when M. genitalium is detected, assuming resistance testing is unavailable?
- Moxifloxacin 400 mg 1x/day for 7 days
- Azithromycin 1 gm orally in a single dose
- Doxycycline 100 mg orally 2x/day for 7 days (correct)
- Levofloxacin 500 mg orally 1x/day for 7 days
Which medication should be administered after doxycycline if moxifloxacin cannot be used for M. genitalium treatment?
Which medication should be administered after doxycycline if moxifloxacin cannot be used for M. genitalium treatment?
- Azithromycin 1 gm orally in a single dose (correct)
- Azithromycin 500 mg orally 1x/day
- Moxifloxacin 400 mg 1x/day for 7 days
- Amoxicillin 500 mg orally 3x/day for 7 days
In pregnant individuals, what is the recommended treatment for M. genitalium?
In pregnant individuals, what is the recommended treatment for M. genitalium?
- Azithromycin 1 gm orally in a single dose (correct)
- Azithromycin 500 mg orally 1x/day
- Moxifloxacin 400 mg 1x/day
- Doxycycline 100 mg orally 2x/day
For how long should doxycycline be administered to adults and adolescents in the treatment of M. genitalium?
For how long should doxycycline be administered to adults and adolescents in the treatment of M. genitalium?
What should be the follow-up treatment after levofloxacin if M. genitalium is confirmed?
What should be the follow-up treatment after levofloxacin if M. genitalium is confirmed?
Which treatment is available for children with a confirmed M. genitalium infection?
Which treatment is available for children with a confirmed M. genitalium infection?
What is the recommended dosage of azithromycin when it is used as the first treatment option?
What is the recommended dosage of azithromycin when it is used as the first treatment option?
For individuals where moxifloxacin is not suitable after doxycycline, which alternative is typically suggested?
For individuals where moxifloxacin is not suitable after doxycycline, which alternative is typically suggested?
What is the primary recommended regimen for treating Bacterial Vaginosis?
What is the primary recommended regimen for treating Bacterial Vaginosis?
In the treatment of Lymphogranuloma Venereum, which of the following is considered an alternative regimen?
In the treatment of Lymphogranuloma Venereum, which of the following is considered an alternative regimen?
Which treatment option is appropriate for a patient with Nongonococcal Urethritis (NGU)?
Which treatment option is appropriate for a patient with Nongonococcal Urethritis (NGU)?
What is a key aspect of STI treatment beyond pharmacological regimens?
What is a key aspect of STI treatment beyond pharmacological regimens?
What regimen is recommended for Cervicitis?
What regimen is recommended for Cervicitis?
For Persistent or Recurrent NGU, testing for which pathogen is recommended?
For Persistent or Recurrent NGU, testing for which pathogen is recommended?
Which alternative regimen can be used for Bacterial Vaginosis?
Which alternative regimen can be used for Bacterial Vaginosis?
Which oral medication is a primary treatment option for Chlamydial Infections?
Which oral medication is a primary treatment option for Chlamydial Infections?
Which of the following is NOT an alternative regimen for treating Lymphogranuloma Venereum?
Which of the following is NOT an alternative regimen for treating Lymphogranuloma Venereum?
Which is a key factor influencing the choice of therapeutic regimens in STI treatment?
Which is a key factor influencing the choice of therapeutic regimens in STI treatment?
What is the recommended duration for administering doxycycline to adults and adolescents for M. genitalium treatment?
What is the recommended duration for administering doxycycline to adults and adolescents for M. genitalium treatment?
Which medication is recommended for pregnant individuals with M. genitalium?
Which medication is recommended for pregnant individuals with M. genitalium?
If moxifloxacin cannot be used, which medication is given after doxycycline for M. genitalium treatment?
If moxifloxacin cannot be used, which medication is given after doxycycline for M. genitalium treatment?
In treatment administration for M. genitalium, what is the dosage of azithromycin given on the first day?
In treatment administration for M. genitalium, what is the dosage of azithromycin given on the first day?
Which of the following is NOT a regimen for treating a confirmed M. genitalium infection?
Which of the following is NOT a regimen for treating a confirmed M. genitalium infection?
How frequently is doxycycline administered to adults and adolescents during the 7-day treatment?
How frequently is doxycycline administered to adults and adolescents during the 7-day treatment?
What is the indicated follow-up treatment after levofloxacin in the M. genitalium treatment regimen?
What is the indicated follow-up treatment after levofloxacin in the M. genitalium treatment regimen?
What is the dosage of levofloxacin when treating M. genitalium in adults and adolescents?
What is the dosage of levofloxacin when treating M. genitalium in adults and adolescents?
What is the primary recommended regimen for treating Bacterial Vaginosis?
What is the primary recommended regimen for treating Bacterial Vaginosis?
Which of the following is an alternative regimen for treating Lymphogranuloma Venereum?
Which of the following is an alternative regimen for treating Lymphogranuloma Venereum?
In the treatment of Nongonococcal Urethritis (NGU), which regimen is recommended?
In the treatment of Nongonococcal Urethritis (NGU), which regimen is recommended?
Which drug is not considered an alternative for Bacterial Vaginosis?
Which drug is not considered an alternative for Bacterial Vaginosis?
What is a key component of STI treatment aside from pharmacological regimens?
What is a key component of STI treatment aside from pharmacological regimens?
Which alternative regimen is suggested for Cervicitis?
Which alternative regimen is suggested for Cervicitis?
For Persistent or Recurrent NGU, testing for which pathogen is advised?
For Persistent or Recurrent NGU, testing for which pathogen is advised?
When treating Lymphogranuloma Venereum, how long should doxycycline be administered?
When treating Lymphogranuloma Venereum, how long should doxycycline be administered?
What is the recommended dosage of azithromycin for treating Cervicitis?
What is the recommended dosage of azithromycin for treating Cervicitis?
Which treatment should be considered in cases of substantial drug allergy for NGU?
Which treatment should be considered in cases of substantial drug allergy for NGU?
Study Notes
Overview of CDC STI Treatment Guidelines, 2021
- Presents recommended therapeutic regimens for sexually transmitted infections (STIs) in a wall chart format.
- Regimens are listed alphabetically unless prioritized by efficacy, cost, or convenience.
- Recommended regimens should be primarily used, with alternatives considered only for significant drug allergies or contraindications.
- Emphasizes the importance of partner management in STI treatment.
Key Recommended Regimens
-
Bacterial Vaginosis:
- Recommended: Metronidazole 500 mg orally, twice daily for 7 days.
- Alternatives: Clindamycin 300 mg orally, twice daily for 7 days or various intravaginal options (metronidazole gel, clindamycin ovules, clindamycin cream).
-
Lymphogranuloma Venereum:
- Recommended: Doxycycline 100 mg orally, twice daily for 21 days.
- Alternatives: Azithromycin 1 gm orally, once a week for 3 weeks, or erythromycin base 500 mg orally, four times daily for 21 days.
-
Nongonococcal Urethritis (NGU):
- Recommended: Doxycycline 100 mg orally, twice daily for 7 days.
- Alternatives: Azithromycin 1 gm orally in a single dose, or tinidazole options (2 gm once daily for 2 days, or 1 gm once daily for 5 days).
-
Cervicitis:
- Recommended: Doxycycline 100 mg orally, twice daily for 7 days.
- Alternatives: Azithromycin 1 gm orally in a single dose.
Chlamydial Infections
-
Adults and Adolescents:
- Recommended: Doxycycline 100 mg orally, twice daily for 7 days.
- Alternatives: Azithromycin 1 gm orally in a single dose or levofloxacin 500 mg orally, once daily for 7 days.
-
Pregnancy:
- Recommended: Azithromycin 1 gm orally in a single dose.
- Alternatives: Amoxicillin 500 mg orally, three times daily for 7 days.
Persistent or Recurrent NGU
- Testing for Mycoplasma genitalium is advised.
- If M. genitalium is detected but resistance testing is unavailable:
- Treatment follows an initial regimen of doxycycline, followed by moxifloxacin 400 mg, once daily for 7 days.
Important Notes
- A comprehensive guideline is accessible online at www.cdc.gov/std/treatment.
- Partner management should be part of the treatment process, potentially involving health department cooperation.
Overview of CDC STI Treatment Guidelines, 2021
- Presents recommended therapeutic regimens for sexually transmitted infections (STIs) in a wall chart format.
- Regimens are listed alphabetically unless prioritized by efficacy, cost, or convenience.
- Recommended regimens should be primarily used, with alternatives considered only for significant drug allergies or contraindications.
- Emphasizes the importance of partner management in STI treatment.
Key Recommended Regimens
-
Bacterial Vaginosis:
- Recommended: Metronidazole 500 mg orally, twice daily for 7 days.
- Alternatives: Clindamycin 300 mg orally, twice daily for 7 days or various intravaginal options (metronidazole gel, clindamycin ovules, clindamycin cream).
-
Lymphogranuloma Venereum:
- Recommended: Doxycycline 100 mg orally, twice daily for 21 days.
- Alternatives: Azithromycin 1 gm orally, once a week for 3 weeks, or erythromycin base 500 mg orally, four times daily for 21 days.
-
Nongonococcal Urethritis (NGU):
- Recommended: Doxycycline 100 mg orally, twice daily for 7 days.
- Alternatives: Azithromycin 1 gm orally in a single dose, or tinidazole options (2 gm once daily for 2 days, or 1 gm once daily for 5 days).
-
Cervicitis:
- Recommended: Doxycycline 100 mg orally, twice daily for 7 days.
- Alternatives: Azithromycin 1 gm orally in a single dose.
Chlamydial Infections
-
Adults and Adolescents:
- Recommended: Doxycycline 100 mg orally, twice daily for 7 days.
- Alternatives: Azithromycin 1 gm orally in a single dose or levofloxacin 500 mg orally, once daily for 7 days.
-
Pregnancy:
- Recommended: Azithromycin 1 gm orally in a single dose.
- Alternatives: Amoxicillin 500 mg orally, three times daily for 7 days.
Persistent or Recurrent NGU
- Testing for Mycoplasma genitalium is advised.
- If M. genitalium is detected but resistance testing is unavailable:
- Treatment follows an initial regimen of doxycycline, followed by moxifloxacin 400 mg, once daily for 7 days.
Important Notes
- A comprehensive guideline is accessible online at www.cdc.gov/std/treatment.
- Partner management should be part of the treatment process, potentially involving health department cooperation.
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Description
This quiz covers the recommended therapeutic regimens for sexually transmitted infections (STIs) as outlined in the CDC's 2021 guidelines. It includes specific treatments for conditions like bacterial vaginosis and lymphogranuloma venereum. Understanding these regimens is crucial for effective STI management and partner care.
