CDC STI Treatment Guidelines 2021 Summary
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Questions and Answers

Match the following STIs with their recommended regimens:

Bacterial Vaginosis = Metronidazole 500 mg orally 2x/day for 7 days Lymphogranuloma Venereum = Doxycycline 100 mg orally 2x/day for 21 days Nongonococcal Urethritis (NGU) = Doxycycline 100 mg orally 2x/day for 7 days Chlamydial Infections = Doxycycline 100 mg orally 2x/day for 7 days

What is the alternative regimen for Bacterial Vaginosis?

  • Erythromycin base 500 mg orally 4x/day for 3 days
  • Tinidazole 2 gm orally 1x/day for 2 days
  • Azithromycin 1 gm orally in a single dose
  • Clindamycin 300 mg orally 2x/day for 7 days (correct)

    • Partner management is an important component of STI treatment.

    True

    What is the recommended regimen for Chlamydial Infections during pregnancy?

    <p>Azithromycin 1 gm orally in a single dose</p> Signup and view all the answers

    What is the alternative regimen for Lymphogranuloma Venereum?

    <p>Azithromycin 1 gm orally 1x/week for 3 weeks</p> Signup and view all the answers

    For persistent or recurrent Nongonococcal Urethritis (NGU), test for ______.

    <p>Mycoplasma genitalium</p> Signup and view all the answers

    What is the recommended regimen for Bacterial Vaginosis?

    <p>Metronidazole 500 mg orally 2x/day for 7 days</p> Signup and view all the answers

    What should be considered in cases of substantial drug allergy or contraindications?

    <p>Alternative regimens</p> Signup and view all the answers

    Which antibiotic is an alternative regimen for Chlamydial Infections in adults and adolescents?

    <p>Azithromycin 1 gm orally in a single dose</p> Signup and view all the answers

    Doxycycline can be used for treating Lymphogranuloma Venereum.

    <p>True</p> Signup and view all the answers

    The recommended regimen for Nongonococcal Urethritis (NGU) is __________.

    <p>Doxycycline 100 mg orally 2x/day for 7 days</p> Signup and view all the answers

    What is the alternative regimen for Cervicitis?

    <p>Azithromycin 1 gm orally in a single dose</p> Signup and view all the answers

    What is the recommended treatment for pregnant women with Chlamydial Infections?

    <p>Azithromycin 1 gm orally in a single dose</p> Signup and view all the answers

    Study Notes

    Overview of CDC STI Treatment Guidelines, 2021

    • Recommended regimens are prioritized alphabetically unless efficacy, cost, or convenience dictate otherwise.
    • Utilize primary recommended regimens; consider alternatives for significant drug allergies or contraindications.
    • Partner management is crucial; evaluation and treatment of sexual partners can involve local health departments.

    Bacterial Vaginosis

    • Recommended Regimen: Metronidazole 500 mg orally twice daily for 7 days.
    • Alternative Regimens:
      • Clindamycin 300 mg orally twice daily for 7 days.
      • Metronidazole gel 0.75%, one 5 gm applicator intravaginally once daily for 5 days.
      • Clindamycin ovules 100 mg intravaginally at bedtime for 3 days.
      • Clindamycin cream 2%, one 5 gm applicator intravaginally at bedtime for 7 days.
      • Secnidazole 2 gm orally in a single dose.

    Lymphogranuloma Venereum

    • Recommended Regimen: Doxycycline 100 mg orally twice daily for 21 days.
    • Alternative Regimens:
      • Azithromycin 1 gm orally once a week for 3 weeks.
      • Erythromycin base 500 mg orally four times daily for 21 days.

    Nongonococcal Urethritis (NGU)

    • Recommended Regimen: Doxycycline 100 mg orally twice daily for 7 days.
    • Alternative Regimens:
      • Azithromycin 1 gm orally in a single dose.
      • Tinidazole 2 gm orally once daily for 2 days.
      • Azithromycin 500 mg orally in a single dose followed by 250 mg once daily for 4 days.

    Cervicitis

    • Recommended Regimen: Doxycycline 100 mg orally twice daily for 7 days.
    • Alternative Regimen: Azithromycin 1 gm orally in a single dose.

    Chlamydial Infections

    • Adults and Adolescents: Doxycycline 100 mg orally twice daily for 7 days is preferred.
    • Alternative Regimens:
      • Azithromycin 1 gm orally in a single dose.
      • Levofloxacin 500 mg orally once daily for 7 days.

    Pregnancy

    • Recommended Regimen: Azithromycin 1 gm orally in a single dose.
    • Alternative Regimen: Amoxicillin 500 mg orally three times daily for 7 days.

    Pediatric Considerations

    • Specific regimens for infants and children are not detailed in this summary.

    Overview of CDC STI Treatment Guidelines, 2021

    • Recommended regimens are prioritized alphabetically unless efficacy, cost, or convenience dictate otherwise.
    • Utilize primary recommended regimens; consider alternatives for significant drug allergies or contraindications.
    • Partner management is crucial; evaluation and treatment of sexual partners can involve local health departments.

    Bacterial Vaginosis

    • Recommended Regimen: Metronidazole 500 mg orally twice daily for 7 days.
    • Alternative Regimens:
      • Clindamycin 300 mg orally twice daily for 7 days.
      • Metronidazole gel 0.75%, one 5 gm applicator intravaginally once daily for 5 days.
      • Clindamycin ovules 100 mg intravaginally at bedtime for 3 days.
      • Clindamycin cream 2%, one 5 gm applicator intravaginally at bedtime for 7 days.
      • Secnidazole 2 gm orally in a single dose.

    Lymphogranuloma Venereum

    • Recommended Regimen: Doxycycline 100 mg orally twice daily for 21 days.
    • Alternative Regimens:
      • Azithromycin 1 gm orally once a week for 3 weeks.
      • Erythromycin base 500 mg orally four times daily for 21 days.

    Nongonococcal Urethritis (NGU)

    • Recommended Regimen: Doxycycline 100 mg orally twice daily for 7 days.
    • Alternative Regimens:
      • Azithromycin 1 gm orally in a single dose.
      • Tinidazole 2 gm orally once daily for 2 days.
      • Azithromycin 500 mg orally in a single dose followed by 250 mg once daily for 4 days.

    Cervicitis

    • Recommended Regimen: Doxycycline 100 mg orally twice daily for 7 days.
    • Alternative Regimen: Azithromycin 1 gm orally in a single dose.

    Chlamydial Infections

    • Adults and Adolescents: Doxycycline 100 mg orally twice daily for 7 days is preferred.
    • Alternative Regimens:
      • Azithromycin 1 gm orally in a single dose.
      • Levofloxacin 500 mg orally once daily for 7 days.

    Pregnancy

    • Recommended Regimen: Azithromycin 1 gm orally in a single dose.
    • Alternative Regimen: Amoxicillin 500 mg orally three times daily for 7 days.

    Pediatric Considerations

    • Specific regimens for infants and children are not detailed in this summary.

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    Description

    This quiz provides an overview of the CDC’s Sexually Transmitted Infections Treatment Guidelines for 2021. It summarizes recommended therapeutic regimens and offers clinical guidance based on efficacy, cost, and convenience. Test your knowledge on the latest treatments for STIs.

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