CDC STI Treatment Guidelines, 2021
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Questions and Answers

What is the recommended regimen for Lymphogranuloma Venereum?

  • metronidazole 500 mg orally 2x/day for 14 days
  • doxycycline 50 mg orally 2x/day for 14 days
  • azithromycin 500 mg orally 1x/day for 14 days
  • doxycycline 100 mg orally 2x/day for 21 days (correct)
  • In what order are the recommended therapeutic regimens presented in the CDC's Sexually Transmitted Infections Treatment Guidelines?

  • Priority order based on efficacy, cost, and convenience
  • Severity of the disease
  • Chronological order of introduction
  • Alphabetical order (correct)
  • What is an essential component of STI treatment according to the CDC's guidelines?

  • Vaccination
  • Laboratory testing
  • Partner management (correct)
  • Patient education
  • What is an alternative regimen for Bacterial Vaginosis?

    <p>secnidazole 2 gm orally in a single dose</p> Signup and view all the answers

    What is the recommended regimen for Cervicitis?

    <p>doxycycline 100 mg orally 2x/day for 7 days</p> Signup and view all the answers

    What is the primary purpose of the CDC's Sexually Transmitted Infections Treatment Guidelines?

    <p>To serve as a source of clinical guidance</p> Signup and view all the answers

    Where can healthcare providers find complete guidelines for STI treatment?

    <p><a href="http://www.cdc.gov/std/treatment">www.cdc.gov/std/treatment</a></p> Signup and view all the answers

    What is the recommended regimen for Nongonococcal Urethritis (NGU)?

    <p>doxycycline 100 mg orally 2x/day for 7 days</p> Signup and view all the answers

    What is an alternative regimen for Lymphogranuloma Venereum?

    <p>erythromycin base 500 mg orally 4x/day for 21 days</p> Signup and view all the answers

    Under what circumstances can alternative regimens be considered?

    <p>In instances of substantial drug allergy or other contraindications</p> Signup and view all the answers

    What is the recommended regimen for Persistent or Recurrent Nongonococcal Urethritis (NGU)?

    <p>test for Mycoplasma genitalium: If M. genitalium is detected</p> Signup and view all the answers

    What is an alternative regimen for Cervicitis?

    <p>azithromycin 1 gm orally in a single dose</p> Signup and view all the answers

    What is an alternative regimen for Bacterial Vaginosis?

    <p>metronidazole gel 0.75%, one 5 gm applicator intravaginally, 1x/day for 5 days</p> Signup and view all the answers

    What is the recommended treatment for adults and adolescents when M.genitalium is detected but moxifloxacin cannot be used?

    <p>doxycycline 100 mg orally 2x/day for 7 days, followed by azithromycin 1 gm orally on first day, followed by azithromycin 500 mg orally 1x/day for 3 days</p> Signup and view all the answers

    What is the recommended treatment for pregnant women?

    <p>amoxicillin 500 mg orally 3x/day for 7 days</p> Signup and view all the answers

    What is the recommended treatment for infants and children?

    <p>not specified in the provided content</p> Signup and view all the answers

    What is the recommended duration of treatment for adults and adolescents when M.genitalium is detected but moxifloxacin cannot be used?

    <p>7 days</p> Signup and view all the answers

    What is the recommended follow-up test for pregnant women after completion of therapy?

    <p>test-of-cure 21 days after completion of therapy</p> Signup and view all the answers

    What is the recommended treatment for adults and adolescents when M.genitalium is detected and resistance testing is available?

    <p>doxycycline 100 mg orally 2x/day for 7 days, followed by moxifloxacin 400 mg 1x/day for 7 days</p> Signup and view all the answers

    What is the recommended dose of azithromycin for pregnant women?

    <p>1 gm orally in a single dose</p> Signup and view all the answers

    What is the recommended treatment for adults and adolescents when M.genitalium is detected but resistance testing is unavailable?

    <p>doxycycline 100 mg orally 2x/day for 7 days, followed by azithromycin 1 gm orally on first day, followed by azithromycin 500 mg orally 1x/day for 3 days</p> Signup and view all the answers

    Study Notes

    STI Treatment Guidelines, 2021

    Bacterial Vaginosis

    • Recommended regimen: metronidazole 500 mg orally 2x/day for 7 days
    • Alternative regimens: clindamycin 300 mg orally 2x/day for 7 days, metronidazole gel 0.75%, one 5 gm applicator intravaginally, 1x/day for 5 days, clindamycin ovules 100 mg intravaginally at bedtime for 3 days, secnidazole 2 gm orally in a single dose

    Lymphogranuloma Venereum

    • Recommended regimen: doxycycline 100 mg orally 2x/day for 21 days
    • Alternative regimens: azithromycin 1 gm orally 1x/week for 3 weeks, erythromycin base 500 mg orally 4x/day for 21 days

    Nongonococcal Urethritis (NGU)

    • Recommended regimen: doxycycline 100 mg orally 2x/day for 7 days
    • Alternative regimens: azithromycin 1 gm orally in a single dose, tinidazole 2 gm orally 1x/day for 2 days, azithromycin 500 mg orally in a single dose, THEN 250 mg 1x/day for 4 days

    Cervicitis

    • Recommended regimen: doxycycline 100 mg orally 2x/day for 7 days
    • Alternative regimen: azithromycin 1 gm orally in a single dose

    Chlamydial Infections

    • Recommended regimen for adults and adolescents: doxycycline 100 mg orally 2x/day for 7 days
    • Alternative regimens for adults and adolescents: azithromycin 1 gm orally in a single dose, levofloxacin 500 mg orally 1x/day for 7 days
    • Recommended regimen for pregnancy: azithromycin 1 gm orally in a single dose
    • Alternative regimen for pregnancy: amoxicillin 500 mg orally 3x/day for 7 days

    Persistent or Recurrent NGU

    • Test for Mycoplasma genitalium: doxycycline 100 mg orally 2x/day for 7 days, FOLLOWED BY moxifloxacin 400 mg 1x/day for 7 days
    • For settings without resistance testing and when moxifloxacin cannot be used: doxycycline 100 mg orally 2x/day for 7 days, FOLLOWED BY azithromycin 1 gm orally on first day, FOLLOWED BY azithromycin 500 mg orally 1x/day for 3 days and a test-of-cure 21 days after completion of therapy

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    Description

    Summary of CDC's 2021 Sexually Transmitted Infections Treatment Guidelines, providing recommended regimens for clinical guidance.

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