Podcast
Questions and Answers
What is the primary function of tumor necrosis factor produced by white blood cells?
What is the primary function of tumor necrosis factor produced by white blood cells?
Which type of bone marrow transplant uses the patient's own marrow?
Which type of bone marrow transplant uses the patient's own marrow?
What type of environment is necessary before and during bone marrow transplantation?
What type of environment is necessary before and during bone marrow transplantation?
What is a common emotional response patients may experience during the process of treatment?
What is a common emotional response patients may experience during the process of treatment?
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Which of the following is a recommended approach for supporting patients undergoing cancer treatment?
Which of the following is a recommended approach for supporting patients undergoing cancer treatment?
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What is the primary treatment for managing symptoms associated with neutropenia in cancer patients?
What is the primary treatment for managing symptoms associated with neutropenia in cancer patients?
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Which of the following lab results indicates anemia in a cancer patient?
Which of the following lab results indicates anemia in a cancer patient?
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What nursing intervention is critical for a patient experiencing tumor lysis syndrome?
What nursing intervention is critical for a patient experiencing tumor lysis syndrome?
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Which medication is used to prevent the formation of uric acid during chemotherapy for tumor lysis syndrome?
Which medication is used to prevent the formation of uric acid during chemotherapy for tumor lysis syndrome?
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During chemotherapy, a patient may experience late symptoms of tumor lysis syndrome. Which of the following is a late symptom?
During chemotherapy, a patient may experience late symptoms of tumor lysis syndrome. Which of the following is a late symptom?
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Which grade of malignancy is characterized by no resemblance to parent tissue?
Which grade of malignancy is characterized by no resemblance to parent tissue?
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What does the 'T' in the CAUTION warning signs of cancer signify?
What does the 'T' in the CAUTION warning signs of cancer signify?
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Which of the following tests is specifically used to evaluate for ovarian cancer?
Which of the following tests is specifically used to evaluate for ovarian cancer?
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What type of radiation therapy does not make the patient radioactive?
What type of radiation therapy does not make the patient radioactive?
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What side effect is associated with external radiation treatment?
What side effect is associated with external radiation treatment?
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Which of the following is NOT considered a screening test for cancer?
Which of the following is NOT considered a screening test for cancer?
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What is the primary purpose of laser or cryosurgery in cancer treatment?
What is the primary purpose of laser or cryosurgery in cancer treatment?
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In the context of cancers with limited local spread, which stage is indicated if it spreads extensively locally and regionally?
In the context of cancers with limited local spread, which stage is indicated if it spreads extensively locally and regionally?
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What dietary recommendation is made for patients following radiation treatment?
What dietary recommendation is made for patients following radiation treatment?
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What is a critical nursing intervention for a patient receiving sealed internal radiation?
What is a critical nursing intervention for a patient receiving sealed internal radiation?
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What effective measure can be implemented to limit visitor exposure to a patient receiving unsealed internal radiation?
What effective measure can be implemented to limit visitor exposure to a patient receiving unsealed internal radiation?
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Which side effect from chemotherapy is linked to low levels of infection-fighting neutrophils?
Which side effect from chemotherapy is linked to low levels of infection-fighting neutrophils?
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What should be avoided to minimize the risk of infection in a patient experiencing neutropenia?
What should be avoided to minimize the risk of infection in a patient experiencing neutropenia?
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What precaution is necessary when handling body fluids of a patient undergoing unsealed internal radiation?
What precaution is necessary when handling body fluids of a patient undergoing unsealed internal radiation?
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What describes malignant tumors compared to benign tumors?
What describes malignant tumors compared to benign tumors?
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What is an important observation for a patient undergoing chemotherapy?
What is an important observation for a patient undergoing chemotherapy?
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Which of the following is NOT a risk factor for developing cancer?
Which of the following is NOT a risk factor for developing cancer?
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Which of the following are potential side effects of chemotherapy?
Which of the following are potential side effects of chemotherapy?
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Which of the following is a characteristic of carcinomas?
Which of the following is a characteristic of carcinomas?
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What does primary prevention of cancer involve?
What does primary prevention of cancer involve?
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What stage is designated for cancer that is localized and has not spread beyond its origin?
What stage is designated for cancer that is localized and has not spread beyond its origin?
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Which type of cancer is classified as a blood-forming cancer?
Which type of cancer is classified as a blood-forming cancer?
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Which of the following risk factors is associated with a higher incidence of cancer among African Americans?
Which of the following risk factors is associated with a higher incidence of cancer among African Americans?
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What typically characterizes benign tumors?
What typically characterizes benign tumors?
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Study Notes
Cancer Definition
- Cancer is characterized by abnormal, uncontrolled cell division that invades and crowds out healthy tissue.
- It is a non-discriminatory disease, meaning it can affect any tissue type.
- It is the second leading cause of death in the U.S.
- Higher incidence among African Americans.
Risk Factors/Carcinogens
- Smoking (including tobacco and e-cigarettes)
- Diet high in fat, low in fiber, and inadequate nutrients
- Obesity and inactivity
- Ultraviolet radiation
- Environmental and chemical carcinogens
- Frequent heavy alcohol consumption
- Genetics
Comparison of Neoplasms (Malignant vs. Benign)
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Malignant:*
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Usually rapid growth
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Metastasizes (spreads to other areas)
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Outside capsule
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Irregular, more immovable
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Little resemblance to parent tissue
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Invades tissue
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May recur
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Fatal without treatment
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Benign:*
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Slow growth
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Localized
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Encapsulated
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Smooth, well-defined edges, movable
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Resembles parent tissue
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Crowds tissue
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Rarely reoccurs after removal
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Rarely fatal
Spread of Cancer (Metastasis)
- Diffusion to other body cavities
- Circulation via blood or lymphatic system
Forms of Cancer
- Carcinoma: Most common type; arises from epithelial tissue (e.g., skin, lining of organs)
- Sarcoma: Solid form; arises from connective tissue (e.g., bone, muscle, cartilage)
- Blood-forming: Leukemias, lymphomas (Hodgkin's and non-Hodgkin's), multiple myeloma
Primary Prevention
- Dietary changes
- Lifestyle modifications
Secondary Prevention
- Screening tests:
- SBE (Self breast exam)
- Clinical breast exam
- Mammograms
- Digital rectal exams
- Pap Smear
- Stop smoking
- Prostate exam and/or PSA
- Self skin examination
Classification of Malignancies (Grading and Staging)
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Grading:*
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GX: Normal tissue
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G1: Well-differentiated
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G2: Moderately differentiated
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G3: Poorly differentiated
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G4: Undifferentiated/poor resemblance to parent tissue
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Staging:*
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Stage 0: Cancer in situ (confined to original site)
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Stage 1-4: Increasing extent from localized to regional spread to metastasis
Warning Signs of Cancer
- Change in bowel or bladder habits
- Sore that does not heal
- Unusual bleeding or discharge
- Thickening or lump
- Indigestion or difficulty swallowing
- Obvious change in wart or mole
- Nagging cough or hoarseness
- White patches on tongue or inside mouth
Know Your ABCDE's (Skin Cancer)
- Asymmetry: One half doesn't match the other
- Border: Irregular borders
- Color: Variety of colors (brown, tan, black)
- Diameter: Larger than a pencil eraser (1/4 inch)
- Evolution: Change in size, shape, color, elevation
Diagnostic/Screening Tests
- Pap smear
- Biopsy
- Bronchoscopy
- EGD/colonoscopy/flexible sigmoidoscopy
- Mammograms
- GI series (UGI, BE)
- CT scans
- PET scans
- MRI
- Ultrasounds
- Radioisotope studies
- Lab tests (e.g., CEA, CA-125, PSA, CA-19-9, occult blood test)
Treatment - Surgery
- Often primary, curative, palliative, or diagnostic
- Newer techniques include laser and cryosurgery
Treatment - Radiation
- Damages DNA and disrupts cell division in cancerous cells, and occasionally normal cells nearby.
- Can be used alone or as an adjunct therapy.
- External Beam: Patient is not radioactive, sites marked with ink, shielded areas. Side effects include radiation sickness, stomatitis, alopecia, cystitis, bone marrow depression, and pneumonitis.
- Sealed Internal Radiation: Implants are placed near cancer site. Types include vaginal/uterus, head and neck. Nursing interventions focus on shielding, avoiding certain activities, and monitoring.
- Unsealed Internal Radiation: Patient is a source of radioactivity. Nursing interventions require using specific utensils, limiting visitors, and appropriate precautions and hygiene.
Treatment - Chemotherapy
- Acts systemically, affecting both cancerous and healthy cells, especially those in the GI system.
- Aims for cure, control, or palliative care. Common side effects include leukopenia, stomatitis, thrombocytopenia, alopecia, and assessing for infection.
Treatment - Targeted Therapy / Biotherapy
- Uses immunotherapy, human growth factors, and biological response modifiers, like interferons, interleukins, and tumor necrosis factor.
- Aims for antitumor effects via activating a variety of responses.
- Colony stimulating factors (e.g., G-CSF) promote growth of blood cells (granulocytes, RBCs).
Treatment - Bone Marrow Transplant
- Replaces diseased or damaged bone marrow with healthy marrow. Types include autologous (patient's own marrow), allogenic (compatible donor tissue), syngeneic (identical twins), and related/unrelated donors.
- Pre-transplant treatment typically involves chemo and/or radiation. Precautions for germ-free environment and recovery time are necessary.
Emotional Support
- Understanding the patient's perspective.
- Addressing anxiety, depression, and potential feelings of punishment associated with the illness.
- Encouraging patient progress and understanding the grieving process.
- Providing support groups and encouraging participation in self-help groups.
Rehab
- Encouraging patients to return to normal activities
- Supporting independence as much as possible
Other Key Considerations (from various slides)
- Cancer classifications: Carcinoma, sarcoma, blood-forming
- Warning signs: Comprehensive list across various body systems
- Cancer stages: Described as Stage 0, 1, 2, 3, and 4
- Treatment focus: Comfort, altered body image, nutrition, chemotherapy, evaluate response, respite for caretakers
- Review of ATI AMS cancer chapters.
- Tumor lysis syndrome: Emergency associated with rapid cancer cell death, including electrolyte imbalances (hyperkalemia, hyperuricemia). Nursing interventions involve hydration and medications (e.g., allopurinol)
- Anemia with chemotherapy: Potential for low hemoglobin levels (anemia) as a complication requiring rest, nutrition, and in some cases blood transfusions
- Neutropenia: Low white blood cell count, increasing risk of infection; treatment involves medications like colony stimulating factors. Nursing interventions focus on preventing infection and promoting hygiene.
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Description
Test your knowledge on the functions and treatments related to cancer management. This quiz covers topics like tumor necrosis factor, bone marrow transplants, emotional responses, and nursing interventions during cancer treatment. Enhance your understanding of crucial aspects in oncology care.