Podcast
Questions and Answers
What is the main mode of action of 5-Fluorouracil (5-FU)?
What is the main mode of action of 5-Fluorouracil (5-FU)?
- Inhibition of thymidylate synthase (TS) (correct)
- Incorporation of FdUTP into RNA resulting in alteration in RNA processing
- Activation of thymineless death
- Incorporation of FUTP into DNA resulting in inhibition of DNA synthesis
What are the possible treatments for tumors according to the text?
What are the possible treatments for tumors according to the text?
- Surgery and systemic chemotherapy only
- Local radiation and systemic chemotherapy only
- Surgery and local radiation only
- Surgery, local radiation, and/or systemic chemotherapy (correct)
What is the mechanism of action of most anticancer antibiotics?
What is the mechanism of action of most anticancer antibiotics?
- Inhibition of DNA topoisomerases (correct)
- Production of free radicals
- Interference with cell division
- Prevention of DNA replication
Anticancer antibiotics are isolated from?
Anticancer antibiotics are isolated from?
What makes bleomycin different from other anticancer antibiotics in terms of its mode of action?
What makes bleomycin different from other anticancer antibiotics in terms of its mode of action?
How do anticancer antibiotics like doxorubicin and bleomycin affect DNA?
How do anticancer antibiotics like doxorubicin and bleomycin affect DNA?
What is the main mechanism of action of Doxorubicin?
What is the main mechanism of action of Doxorubicin?
Which type of cancer is NOT listed as a use for Doxorubicin?
Which type of cancer is NOT listed as a use for Doxorubicin?
How is Doxorubicin metabolized when administered intravenously?
How is Doxorubicin metabolized when administered intravenously?
What is a potential adverse effect of Doxorubicin administration?
What is a potential adverse effect of Doxorubicin administration?
What is the main adverse effect of Doxorubicin administration?
What is the main adverse effect of Doxorubicin administration?
How is the cardiotoxicity of Doxorubicin reduced?
How is the cardiotoxicity of Doxorubicin reduced?
Which organ is NOT affected by Doxorubicin due to its inability to penetrate it?
Which organ is NOT affected by Doxorubicin due to its inability to penetrate it?
How is Doxorubicin primarily excreted from the body?
How is Doxorubicin primarily excreted from the body?
