14 Questions
What is the frequency of the treatment LV5FU2?
Every 14 days
What is the dosage of cisplatine in the LV5FU2 treatment?
50 mg/m2
What is the indication for the FOLFIRI treatment?
Adénocarcinomes, after failure of 5FU-platine
What is the standard treatment for oesophage cervical and tiers supérieur?
Radiochimiothérapie concomitante
What is the survival rate at 5 years for stage 0?
>95%
What is the purpose of hydration before and after cisplatine treatment?
To reduce the side effects of cisplatine
What is the definition of esophageal cancer?
A group of malignant tumors developed from different tunics of the esophagus
What is the frequency of esophageal cancer?
It is the 3rd most common digestive cancer
What is the incidence of esophageal cancer in high-risk areas?
More than 150/100 000 habitants
What is the common symptom of esophageal cancer that is often neglected?
Dysphagia
What is the primary treatment for esophageal cancer?
Surgery
What is the purpose of a bilan pre-therapeutique?
To evaluate the patient's overall health status
What is the chemotherapy protocol used in the treatment of esophageal cancer?
All of the above
What is the prognosis of esophageal cancer?
Poor
Study Notes
Definition and Interest
- Cancer of the esophagus refers to all primary malignant tumors that develop from different tunics of the esophagus.
- The frequency of esophageal cancer is increasing, and it is often diagnosed late, making treatment challenging.
Anatomical Overview
- No key points mentioned in this section.
Epidemiology
- Esophageal cancer is the 3rd most common digestive cancer and 9th most common cancer worldwide.
- High-incidence zones include China, South Africa (Transkei), Iran, and South America, with an incidence rate of >150/100,000 inhabitants.
- Intermediate-incidence zones include France and India, with an incidence rate of 10-20/100,000 inhabitants.
- Low-incidence zones have an incidence rate of <15%.
Anatomical Pathology
- No key points mentioned in this section.
Diagnosis
- No key points mentioned in this section.
Extension Assessment
- No key points mentioned in this section.
Classification
- No key points mentioned in this section.
Pre-Therapeutic Assessment
- Evaluation of dental status, cardiovascular status with ECG, and assessment of therapeutic efficacy after 2-3 cycles of chemotherapy.
Treatment
- Chemotherapy protocols: 5FU continuous, Cisplatine, FOLFOX 4, FOLFOX 4 simplified, LV5FU2, LV5FU2 simplified, Navelbine +/- Cisplatine, and FOLFIRI.
- Treatment options for metastatic disease: symptomatic treatment, palliative chemotherapy, radiochemotherapy, and therapeutic abstention.
Surveillance
- No key points mentioned in this section.
Prognostic Factors
- No key points mentioned in this section.
Conclusion
- 5-year survival rates: Stage 0: >95%, Stage I: 50-80%, Stage IIA: 30-40%, Stage IIB: 10-30%, Stage III: 10-15%, and Stage IV: M1a: unknown.
This quiz covers the definition, anatomy, epidemiology, diagnosis, treatment, and prognosis of cancer of the esophagus. It also discusses the classification, staging, and pre-therapeutic evaluation of the disease.
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