Cancer of the Esophagus

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Questions and Answers

What is the frequency of the treatment LV5FU2?

  • Every 21 days
  • Every 7 days
  • Every 30 days
  • Every 14 days (correct)

What is the dosage of cisplatine in the LV5FU2 treatment?

  • 50 mg/m2 (correct)
  • 100 mg/m2
  • 75 mg/m2
  • 80 mg/m2

What is the indication for the FOLFIRI treatment?

  • Maladie métastatique ganglionnaire M1a
  • Adénocarcinomes, after failure of 5FU-platine (correct)
  • Maladie métastatique viscérale
  • Oesophage cervical et tiers supérieur

What is the standard treatment for oesophage cervical and tiers supérieur?

<p>Radiochimiothérapie concomitante (D)</p> Signup and view all the answers

What is the survival rate at 5 years for stage 0?

<p>&gt;95% (C)</p> Signup and view all the answers

What is the purpose of hydration before and after cisplatine treatment?

<p>To reduce the side effects of cisplatine (A)</p> Signup and view all the answers

What is the definition of esophageal cancer?

<p>A group of malignant tumors developed from different tunics of the esophagus (C)</p> Signup and view all the answers

What is the frequency of esophageal cancer?

<p>It is the 3rd most common digestive cancer (D)</p> Signup and view all the answers

What is the incidence of esophageal cancer in high-risk areas?

<p>More than 150/100 000 habitants (D)</p> Signup and view all the answers

What is the common symptom of esophageal cancer that is often neglected?

<p>Dysphagia (A)</p> Signup and view all the answers

What is the primary treatment for esophageal cancer?

<p>Surgery (D)</p> Signup and view all the answers

What is the purpose of a bilan pre-therapeutique?

<p>To evaluate the patient's overall health status (C)</p> Signup and view all the answers

What is the chemotherapy protocol used in the treatment of esophageal cancer?

<p>All of the above (D)</p> Signup and view all the answers

What is the prognosis of esophageal cancer?

<p>Poor (B)</p> Signup and view all the answers

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Study Notes

Definition and Interest

  • Cancer of the esophagus refers to all primary malignant tumors that develop from different tunics of the esophagus.
  • The frequency of esophageal cancer is increasing, and it is often diagnosed late, making treatment challenging.

Anatomical Overview

  • No key points mentioned in this section.

Epidemiology

  • Esophageal cancer is the 3rd most common digestive cancer and 9th most common cancer worldwide.
  • High-incidence zones include China, South Africa (Transkei), Iran, and South America, with an incidence rate of >150/100,000 inhabitants.
  • Intermediate-incidence zones include France and India, with an incidence rate of 10-20/100,000 inhabitants.
  • Low-incidence zones have an incidence rate of <15%.

Anatomical Pathology

  • No key points mentioned in this section.

Diagnosis

  • No key points mentioned in this section.

Extension Assessment

  • No key points mentioned in this section.

Classification

  • No key points mentioned in this section.

Pre-Therapeutic Assessment

  • Evaluation of dental status, cardiovascular status with ECG, and assessment of therapeutic efficacy after 2-3 cycles of chemotherapy.

Treatment

  • Chemotherapy protocols: 5FU continuous, Cisplatine, FOLFOX 4, FOLFOX 4 simplified, LV5FU2, LV5FU2 simplified, Navelbine +/- Cisplatine, and FOLFIRI.
  • Treatment options for metastatic disease: symptomatic treatment, palliative chemotherapy, radiochemotherapy, and therapeutic abstention.

Surveillance

  • No key points mentioned in this section.

Prognostic Factors

  • No key points mentioned in this section.

Conclusion

  • 5-year survival rates: Stage 0: >95%, Stage I: 50-80%, Stage IIA: 30-40%, Stage IIB: 10-30%, Stage III: 10-15%, and Stage IV: M1a: unknown.

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