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Questions and Answers
What is the brand name for Bupropion?
What is the brand name for Bupropion?
- Wellbutrin® (SR, XL)
- Forfivo® XL
- Zyban®
- All of the above (correct)
What are the indications for the use of Bupropion?
What are the indications for the use of Bupropion?
Depression, associated with seasonal affective disorder; prophylaxis of major depressive disorder; smoking cessation assistance.
What is the mechanism of action of Bupropion?
What is the mechanism of action of Bupropion?
Inhibits weakly the neuronal uptake of dopamine and norepinephrine but does not inhibit monoamine oxidase or the reuptake of serotonin.
What is the most common dosage for extended-release Bupropion?
What is the most common dosage for extended-release Bupropion?
What should you do if a dose of Bupropion is missed?
What should you do if a dose of Bupropion is missed?
How should Bupropion be stored?
How should Bupropion be stored?
What are some common adverse effects of Bupropion?
What are some common adverse effects of Bupropion?
Who should avoid taking Bupropion?
Who should avoid taking Bupropion?
What interactions should be noted for Bupropion?
What interactions should be noted for Bupropion?
What is one recommendation for taking Bupropion?
What is one recommendation for taking Bupropion?
Study Notes
Bupropion Overview
- Brand names include Wellbutrin® (SR, XL), Forfivo® XL, and Zyban®.
- Classified as an aminoketone antidepressant.
Indications for Use
- Treats major depressive disorder and seasonal affective disorder.
- Assists in smoking cessation.
Mechanism of Action
- Inhibits the reuptake of dopamine and norepinephrine.
- Does not affect monoamine oxidase or serotonin levels.
Dosage Directions
- Extended-release (XL): 150 mg to 300 mg once daily, with 300 mg as the most common target.
- Immediate-release: Initiate at 100 mg twice daily, can increase by a maximum of 100 mg/day; usual adult total is 300 mg/day, with a max of 450 mg/day.
- Sustained release: Up to 400 mg/day, typically in two doses, with a target of 300 mg/day.
Missed Dose Instructions
- If a dose is missed, wait for the next scheduled dose; do not double doses.
Storage Instructions
- Store in a cool, dry place away from sunlight.
Efficacy
- Aims to improve depression symptoms or support smoking cessation efforts.
Adverse Effects
- Potential side effects include dizziness, constipation, weight loss, dry mouth, insomnia, sweating, agitation, and tremor.
Contraindications
- Avoid in individuals with seizure disorders, history of bulimia, or anorexia nervosa.
- Increased risk of suicidal thoughts and actions in children, adolescents, and young adults.
Drug Interactions
- Risk of toxicity rises with monoamine oxidase inhibitors and L-dopa.
- Alcohol may decrease seizure threshold.
Other Points
- Recommended to take in the morning to minimize insomnia risk.
- Advisable to avoid alcohol.
- Monitor for any sudden mood or behavior changes.
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Description
This quiz provides flashcards on Bupropion, a medication commonly used for depression and smoking cessation. You'll learn about the brand names, generic names, and various indications for use. Test your knowledge on this important pharmaceutical agent!
