Wellbutrin (bupropion) Flashcards
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Questions and Answers

What is the drug classification of Wellbutrin?

  • MAOI
  • Atypical antidepressant (correct)
  • SSRI
  • Tricyclic antidepressant
  • The typical dose range for Wellbutrin is ___ mg daily.

    200-300

    What are the pharmacological actions of Wellbutrin?

    Decrease reuptake of dopamine, serotonin & norepinephrine.

    Which of the following are therapeutic uses of Wellbutrin? (Select all that apply)

    <p>Treat seasonal affective disorder (A), Treat ADHD in adults (C), Diminish depression (D)</p> Signup and view all the answers

    Name two side effects of Wellbutrin.

    <p>Seizures, dry mouth.</p> Signup and view all the answers

    Which of the following medications should not be taken with Wellbutrin? (Select all that apply)

    <p>Antidepressants (A), Oral hypoglycemic meds (B), Benzodiazepines (C), MOAIs (D)</p> Signup and view all the answers

    What nursing intervention is recommended to minimize seizure risk for Wellbutrin?

    <p>Administer in equally spaced doses.</p> Signup and view all the answers

    It is safe to administer Wellbutrin if the patient has a history of seizures.

    <p>False (B)</p> Signup and view all the answers

    What indicates effectiveness of Wellbutrin medication?

    <p>Increased sense of well-being, renewed interest in surroundings.</p> Signup and view all the answers

    Study Notes

    Wellbutrin (Bupropion) Overview

    • Classified as an atypical antidepressant.
    • Administered orally with a dose range of 100 mg three times per day; typical dose is 200-300 mg daily.

    Pharmacological Action

    • Primarily inhibits the reuptake of dopamine.
    • Also decreases the reuptake of serotonin and norepinephrine.

    Therapeutic Uses

    • Treats major depressive disorder and seasonal affective disorder.
    • Approved for adult ADHD treatment.
    • Off-label uses include enhancing sexual desire in women and aiding in nicotine addiction treatment.

    Side Effects and Adverse Effects

    • Potential severe side effects: seizures, suicidal thoughts, agitation, and hallucinations.
    • Other common effects: headaches, aggression, anxiety, dry mouth, nausea/vomiting, and appetite changes.
    • Weight fluctuations, photosensitivity, tremors, and risks of hypo/hyperglycemia may occur.

    Medication and Food Interactions

    • Significant interactions with MAOIs, antidepressants, nicotine replacement therapies, warfarin, and tamoxifen.
    • Caution advised with corticosteroids, OTC stimulants, alcohol, benzodiazepines, and medications for diabetes.

    Nursing Interventions and Client Education

    • Administer doses evenly to minimize seizure risk and take with food to reduce gastrointestinal issues.
    • Regularly monitor mood changes, renal, and hepatic function.
    • Be aware of potential false positives in urine tests for amphetamines.
    • Advise avoidance of driving until effect is known and assess use of OTC and herbal remedies.

    Nursing Administration Concerns

    • Do not exceed 450 mg/day to avoid seizure risk.
    • Administer in the morning.
    • Contraindicated in individuals with a history of seizures, cranial trauma, or those taking oral hypoglycemics if diabetic.
    • Avoid use in patients with alcohol dependence or those withdrawing from alcohol and those addicted to opiates, cocaine, or stimulants.

    Evaluation of Medication Effectiveness

    • Effectiveness is indicated by an increased sense of well-being and renewed interest in daily activities.
    • Note that it may take several months of treatment to observe acute episode improvements.

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    Description

    Test your knowledge on the drug Wellbutrin (bupropion) through these flashcards. Explore its classification, dosage, pharmacological actions, and therapeutic uses. Perfect for students and healthcare professionals alike.

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