BSMLS 3F Mycology & Virology: Arthropod & Rodent-Borne Viruses
80 Questions
1 Views

Choose a study mode

Play Quiz
Study Flashcards
Spaced Repetition
Chat to Lesson

Podcast

Play an AI-generated podcast conversation about this lesson

Questions and Answers

What is the primary site of multiplication of the Togavirus in a susceptible vertebrate host?

  • Lymph node and other tissues
  • Myeloid and lymphoid cells, and vascular endothelium (correct)
  • CNS and bloodstream
  • Skin and joints

What is the role of E2 protein in the transmission of CHKV?

  • Triggers the activation of innate immune response
  • Envelopes the nucleocapsid
  • Allows the virus to enter the host
  • Mediates cell attachment (correct)

What is the typical incubation period of CHKV?

  • 5-7 days
  • 10-14 days
  • 1-2 days
  • 2-4 days (correct)

What is the name of the interferon produced via activation of non-hematopoietic cells during CHKV infection?

<p>Type 1 interferon (IFN) (D)</p> Signup and view all the answers

What is the diameter of the nucleocapsid of the Togavirus?

<p>70 nm (C)</p> Signup and view all the answers

What is the name of the cycle of transmission that involves an animal (wild animal) as a major host?

<p>Sylvatic Cycle (A)</p> Signup and view all the answers

What is the type of viral fusion protein that E1 is classified as?

<p>Class II (A)</p> Signup and view all the answers

What is the major host of the CHKV?

<p>Humans (D)</p> Signup and view all the answers

What is the role of the urban cycle of transmission in CHKV?

<p>Transmission from human to mosquito to human (A)</p> Signup and view all the answers

What is the size of the genome of the Togavirus?

<p>11-12 kb (C)</p> Signup and view all the answers

What is the percentage of cases where joint pain is a clinical manifestation of dengue?

<p>92% (B)</p> Signup and view all the answers

What is the duration of recovery from joint pain in dengue patients?

<p>1 week (B)</p> Signup and view all the answers

What is the age group that is more susceptible to dengue complications?

<p>65 years old or above (D)</p> Signup and view all the answers

What is the primary method of preventing dengue transmission?

<p>Removing stagnant water (C)</p> Signup and view all the answers

What is the result of infection in pregnant women?

<p>The virus can infect the developing fetus (C)</p> Signup and view all the answers

What is the family of viruses that dengue belongs to?

<p>Flaviviridae (A)</p> Signup and view all the answers

What is the common name of the virus that causes dengue?

<p>Flavivirus (C)</p> Signup and view all the answers

What is the type of nucleic acid that makes up the genetic material of dengue virus?

<p>RNA (B)</p> Signup and view all the answers

What is the result of infection in later stages of pregnancy?

<p>Splenomegaly and osteomyelitis among other birth defects (C)</p> Signup and view all the answers

What is the primary reservoir of the DENV virus?

<p>Humans (D)</p> Signup and view all the answers

What is the typical incubation period of DENV?

<p>3-14 days (D)</p> Signup and view all the answers

What is the name of the disease caused by the virus that is similar to dengue?

<p>Zika fever (A)</p> Signup and view all the answers

What is the result of intrauterine infection during the first trimester of pregnancy?

<p>Low birth weight, mental retardation, deafness, and congenital heart disease (B)</p> Signup and view all the answers

What is the size of the DENV virus?

<p>40-60 nm in diameter (D)</p> Signup and view all the answers

What is the genome structure of the DENV virus?

<p>Positive-sense, single-stranded RNA (C)</p> Signup and view all the answers

What is the primary method of diagnosing DENV infection?

<p>Detection of specific serum IgG and IgM antibodies (C)</p> Signup and view all the answers

What is the role of infected macrophages in DENV infection?

<p>They produce signaling proteins that help to combat the infection (B)</p> Signup and view all the answers

What is the result of a high viral load in DENV infection?

<p>Severe symptoms and a high risk of mortality (D)</p> Signup and view all the answers

What is the significance of collecting two serum samples in diagnosing DENV infection?

<p>To identify whether the patient has developed antibodies against the virus and to monitor the response to treatment (C)</p> Signup and view all the answers

What is the current status of vaccine availability for DENV infection?

<p>There is no vaccine available to treat DENV infection (C)</p> Signup and view all the answers

What is the result of intrauterine infection during the first trimester of pregnancy?

<p>Low birth weight, mental retardation, deafness, congenital heart disease, and neurologic defects (C)</p> Signup and view all the answers

What is the primary method of diagnosing DENV infection?

<p>Detection of specific serum IgG and IgM antibodies (B)</p> Signup and view all the answers

What is the primary reservoir of the DENV virus?

<p>Humans (A)</p> Signup and view all the answers

What is the role of infected macrophages in DENV infection?

<p>Production of signaling proteins (B)</p> Signup and view all the answers

What is the result of a high viral load in DENV infection?

<p>Severe symptoms (D)</p> Signup and view all the answers

What is the significance of collecting two serum samples in diagnosing DENV infection?

<p>To confirm the diagnosis (A)</p> Signup and view all the answers

What is the common name of the virus that causes dengue?

<p>Dengue virus (D)</p> Signup and view all the answers

What is the type of viral genome of the DENV virus?

<p>Positive-sense, single stranded RNA (B)</p> Signup and view all the answers

What is the primary vector of DENV transmission?

<p>Aedes mosquito (A)</p> Signup and view all the answers

What is the role of E2 protein in the transmission of DENV?

<p>Not specified in the text (C)</p> Signup and view all the answers

What is the result of CHKV replication in the central nervous system?

<p>Dependence on the ability of the virus to cross the blood-brain barrier (C)</p> Signup and view all the answers

What is the role of Type 1 interferon in CHKV infection?

<p>Trigger the activation of an innate immune response (C)</p> Signup and view all the answers

What is the primary route of transmission of CHKV?

<p>Through the bite of an infected mosquito (D)</p> Signup and view all the answers

What is the target cell type of CHKV in humans?

<p>Epithelial cells and fibroblasts (D)</p> Signup and view all the answers

What is the classification of the E1 protein in CHKV?

<p>Class II viral fusion protein (B)</p> Signup and view all the answers

What is the characteristic of the genome of CHKV?

<p>Positive-sense, single-stranded RNA (B)</p> Signup and view all the answers

What is the typical duration of viremia in CHKV infection?

<p>Several days (A)</p> Signup and view all the answers

What is the role of the urban cycle in CHKV transmission?

<p>Transmission from human to mosquito to human (C)</p> Signup and view all the answers

What is the primary vector of CHKV transmission?

<p>Aedes aegypti (B)</p> Signup and view all the answers

What is the outcome of CHKV infection in pregnant women?

<p>Vertical transmission to the fetus (B)</p> Signup and view all the answers

What is the most common clinical manifestation of dengue?

<p>Joint pain (B)</p> Signup and view all the answers

What is the outcome of infection in pregnant women?

<p>Congenital anomalies in the fetus (C)</p> Signup and view all the answers

What is the primary method of preventing dengue transmission?

<p>Removing stagnant water (D)</p> Signup and view all the answers

What is the family of viruses that dengue belongs to?

<p>Flaviviridae (D)</p> Signup and view all the answers

What is the duration of recovery from joint pain in dengue patients?

<p>1 week (A)</p> Signup and view all the answers

What is the age group that is more susceptible to dengue complications?

<p>People over 65 years old (B)</p> Signup and view all the answers

What is the result of infection in later stages of pregnancy?

<p>Splenomegaly and osteomyelitis (A)</p> Signup and view all the answers

What is the common name of the virus that causes dengue?

<p>Flavivirus (B)</p> Signup and view all the answers

What is the outcome of infection in an individual?

<p>Immunity to dengue (D)</p> Signup and view all the answers

What is the type of nucleic acid that makes up the genetic material of dengue virus?

<p>RNA (D)</p> Signup and view all the answers

Which of the following is a common complication of dengue infection in pregnant women?

<p>Splenomegaly (B)</p> Signup and view all the answers

What is the approximate percentage of dengue cases that exhibit joint pain as a clinical manifestation?

<p>92% (B)</p> Signup and view all the answers

What is the typical duration of recovery from joint pain in dengue patients?

<p>1 week (B)</p> Signup and view all the answers

Which of the following is a method of preventing dengue transmission?

<p>Removing stagnant water (B)</p> Signup and view all the answers

What is the family of viruses that dengue belongs to?

<p>Flaviviridae (A)</p> Signup and view all the answers

What is the consequence of infection in later stages of pregnancy?

<p>Congenital anomalies (D)</p> Signup and view all the answers

What is the primary mechanism by which CHKV triggers the activation of an innate immune response?

<p>Through the production of cytokines and chemokines (A)</p> Signup and view all the answers

What is the characteristic of the nucleocapsid of the Togavirus?

<p>It is 70 nm in diameter (B)</p> Signup and view all the answers

What is the primary route of transmission of CHKV in the urban cycle?

<p>From human to mosquito to human (A)</p> Signup and view all the answers

What is the role of fibroblasts in CHKV infection?

<p>They are a target cell type for CHKV replication (C)</p> Signup and view all the answers

What is the consequence of intrauterine infection during the first trimester of pregnancy?

<p>Low birth weight, mental retardation, deafness, congenital heart disease, and neurologic defects (D)</p> Signup and view all the answers

What is the characteristic of the genome of the Togavirus?

<p>It is positive-sense, single-stranded RNA (B)</p> Signup and view all the answers

What is the outcome of CHKV replication in the central nervous system?

<p>It depends on the ability of the virus to cross the blood-brain barrier (D)</p> Signup and view all the answers

What is the structure of the DENV virus?

<p>Spherical, 40-60 nm in diameter (A)</p> Signup and view all the answers

What is the primary method of diagnosing DENV infection?

<p>Detection of specific serum IgG and IgM antibodies (C)</p> Signup and view all the answers

What is the role of infected macrophages in DENV infection?

<p>Produce interferons and cytokines (C)</p> Signup and view all the answers

What is the primary route of transmission of DENV?

<p>Infected female Aedes mosquito bite (D)</p> Signup and view all the answers

What is the result of a high viral load in DENV infection?

<p>Severe symptoms (D)</p> Signup and view all the answers

What is the significance of collecting two serum samples in diagnosing DENV infection?

<p>To confirm the presence of antibodies (B)</p> Signup and view all the answers

What is the current status of vaccine availability for DENV infection?

<p>There is currently no vaccine available (A)</p> Signup and view all the answers

More Like This

Virology: Togaviruses and Arboviruses
12 questions

Virology: Togaviruses and Arboviruses

PrivilegedCoralReef avatar
PrivilegedCoralReef
Arboviruses: Types and Transmission
8 questions

Arboviruses: Types and Transmission

ManeuverableYeti avatar
ManeuverableYeti
Virology Quiz on Arboviruses
48 questions

Virology Quiz on Arboviruses

SuccessfulNavy3461 avatar
SuccessfulNavy3461
Virology Quiz on Hepatitis and Arboviruses
49 questions

Virology Quiz on Hepatitis and Arboviruses

LionheartedChrysoprase7996 avatar
LionheartedChrysoprase7996
Use Quizgecko on...
Browser
Open
Browser
Browser