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Questions and Answers
What is the primary composition difference between colostrum and mature human milk?
What is the primary composition difference between colostrum and mature human milk?
Human mature milk contains more protein than cow's milk.
Human mature milk contains more protein than cow's milk.
False
What is the characteristic color of colostrum?
What is the characteristic color of colostrum?
Deep yellow
Colostrum is secreted from the first sucking day up to ______ days.
Colostrum is secreted from the first sucking day up to ______ days.
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Match the types of milk with their characteristics:
Match the types of milk with their characteristics:
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Which of the following is a significant advantage of breast milk over cow’s milk?
Which of the following is a significant advantage of breast milk over cow’s milk?
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Transitional milk is secreted between the 4th and 10th day of lactation.
Transitional milk is secreted between the 4th and 10th day of lactation.
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What is the average pH of mature human milk?
What is the average pH of mature human milk?
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Which immunoglobulins are found in breast milk that help promote gastrointestinal growth?
Which immunoglobulins are found in breast milk that help promote gastrointestinal growth?
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Breast milk has a composition that can be affected by human error.
Breast milk has a composition that can be affected by human error.
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Name one anti-inflammatory agent found in breast milk.
Name one anti-inflammatory agent found in breast milk.
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Breast milk contains living cells such as white blood cells, macrophages, and __________ that help lower infection rates in infants.
Breast milk contains living cells such as white blood cells, macrophages, and __________ that help lower infection rates in infants.
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Match the following benefits of breastfeeding to their descriptions:
Match the following benefits of breastfeeding to their descriptions:
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What is one growth factor mentioned that supports gastrointestinal function?
What is one growth factor mentioned that supports gastrointestinal function?
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Breastfeeding has no impact on blood glucose levels in infants.
Breastfeeding has no impact on blood glucose levels in infants.
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Which formula is intended for infants with a strong family history of allergies?
Which formula is intended for infants with a strong family history of allergies?
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The fat content in goat's milk formula is higher than that in human milk.
The fat content in goat's milk formula is higher than that in human milk.
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What is the predominant carbohydrate in goat's milk formula?
What is the predominant carbohydrate in goat's milk formula?
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The protein content in soy protein formula ranges from __________ gm/dl.
The protein content in soy protein formula ranges from __________ gm/dl.
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Match the following formulas with their key features:
Match the following formulas with their key features:
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Which component is present in higher concentration in the soy protein formula compared to human milk?
Which component is present in higher concentration in the soy protein formula compared to human milk?
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Goat's milk formula is not widely accepted due to a lack of clinical trials.
Goat's milk formula is not widely accepted due to a lack of clinical trials.
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What is the primary source of carbohydrates in sweetened condensed milk?
What is the primary source of carbohydrates in sweetened condensed milk?
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Human milk contains more protein than non-premium formula.
Human milk contains more protein than non-premium formula.
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What percentage of whey is found in human milk?
What percentage of whey is found in human milk?
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In human milk, the energy yield is __________ kcal/dl.
In human milk, the energy yield is __________ kcal/dl.
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What is the fat content in human milk per deciliter?
What is the fat content in human milk per deciliter?
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Which of the following is NOT a characteristic of goat's milk formula?
Which of the following is NOT a characteristic of goat's milk formula?
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The predominant protein in condensed milk is __________.
The predominant protein in condensed milk is __________.
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Match the following types of milk with their key characteristics:
Match the following types of milk with their key characteristics:
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Which vitamin is significantly higher in evaporated milk compared to human milk?
Which vitamin is significantly higher in evaporated milk compared to human milk?
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Premium formula is intended for infants with feeding difficulties.
Premium formula is intended for infants with feeding difficulties.
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What is the energy content in human milk per deciliter?
What is the energy content in human milk per deciliter?
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In non-premium formula, the fat content is primarily from __________.
In non-premium formula, the fat content is primarily from __________.
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Which formula type has a fat content range that does not exceed 4 gm/dl?
Which formula type has a fat content range that does not exceed 4 gm/dl?
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What is one advantage of lactose?
What is one advantage of lactose?
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Galactose and glucose form a type of cerebroside in the Central Nervous System.
Galactose and glucose form a type of cerebroside in the Central Nervous System.
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What is the primary role of bifidus factor found in oligosaccharides?
What is the primary role of bifidus factor found in oligosaccharides?
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The primary type of protein found in human milk is called __________.
The primary type of protein found in human milk is called __________.
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Which of the following statements is true regarding protein nitrogen in human and cow's milk?
Which of the following statements is true regarding protein nitrogen in human and cow's milk?
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Lactoferrin is found in higher concentrations in cow's milk than in human milk.
Lactoferrin is found in higher concentrations in cow's milk than in human milk.
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Match the following components with their respective percentages in human milk:
Match the following components with their respective percentages in human milk:
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What is the main benefit of promoting the growth of intestinal bacteria?
What is the main benefit of promoting the growth of intestinal bacteria?
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The beneficial effects of oligosaccharides are largely attributed to their ability to support __________ flora.
The beneficial effects of oligosaccharides are largely attributed to their ability to support __________ flora.
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What is one of the roles of proteins in human milk?
What is one of the roles of proteins in human milk?
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Which essential amino acid has the highest content in cow’s milk per 100 ml?
Which essential amino acid has the highest content in cow’s milk per 100 ml?
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Urea is a non-essential amino acid present in human milk.
Urea is a non-essential amino acid present in human milk.
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What is the primary energy source found in human milk?
What is the primary energy source found in human milk?
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The average content of _____ in human milk for Methionine is 25 mg/100 ml.
The average content of _____ in human milk for Methionine is 25 mg/100 ml.
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Match the following non-essential amino acids with their respective content in human milk (mg/100 ml):
Match the following non-essential amino acids with their respective content in human milk (mg/100 ml):
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Which dietary factor significantly affects the composition of fats in human milk?
Which dietary factor significantly affects the composition of fats in human milk?
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The fat content in human milk is lowest during the early mornings.
The fat content in human milk is lowest during the early mornings.
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Which amino acid has the lowest content in human milk?
Which amino acid has the lowest content in human milk?
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Human milk contains _____ mg/100 ml of Glutamate.
Human milk contains _____ mg/100 ml of Glutamate.
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Which chronic illnesses are breastfeeding associated with a reduced risk for in infants?
Which chronic illnesses are breastfeeding associated with a reduced risk for in infants?
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Breastfeeding has no effect on auditory function in infants.
Breastfeeding has no effect on auditory function in infants.
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What benefit does breastfeeding provide regarding child behavior and mental health?
What benefit does breastfeeding provide regarding child behavior and mental health?
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Breastfeeding may result in a slight reduction of blood pressure of approximately __________ mm Hg during childhood.
Breastfeeding may result in a slight reduction of blood pressure of approximately __________ mm Hg during childhood.
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Match the following breastfeeding benefits to their descriptions:
Match the following breastfeeding benefits to their descriptions:
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Which is a long-term benefit of breastfeeding for mothers?
Which is a long-term benefit of breastfeeding for mothers?
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Breastfeeding has a substantial contraceptive effect known as lactation amenorrhea.
Breastfeeding has a substantial contraceptive effect known as lactation amenorrhea.
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What is a primary usage of high-protein formulas?
What is a primary usage of high-protein formulas?
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Premature formulas are designed to support metabolic processes without disruption.
Premature formulas are designed to support metabolic processes without disruption.
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High-protein formulas typically contain __________ gm/dl of protein.
High-protein formulas typically contain __________ gm/dl of protein.
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Match the following formula types with their primary characteristics:
Match the following formula types with their primary characteristics:
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Which vitamin is notably increased in premature formulas compared to human milk?
Which vitamin is notably increased in premature formulas compared to human milk?
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What is the predominant carbohydrate found in high-protein formulas?
What is the predominant carbohydrate found in high-protein formulas?
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Soy protein formulas are suitable for infants with allergies to cow's milk protein.
Soy protein formulas are suitable for infants with allergies to cow's milk protein.
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What is the energy content of a high-protein formula per deciliter?
What is the energy content of a high-protein formula per deciliter?
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Human milk provides __________ grams/dl of protein.
Human milk provides __________ grams/dl of protein.
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What is the predominant carbohydrate in human milk?
What is the predominant carbohydrate in human milk?
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Goat's milk formula is widely accepted due to its established clinical trials.
Goat's milk formula is widely accepted due to its established clinical trials.
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What percentage of whey protein is found in human milk?
What percentage of whey protein is found in human milk?
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The fat content in hypoallergenic formula is approximately ______ gm/dl.
The fat content in hypoallergenic formula is approximately ______ gm/dl.
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Match the following types of formula with their intended use:
Match the following types of formula with their intended use:
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Which of the following components is higher in soy protein formula compared to human milk?
Which of the following components is higher in soy protein formula compared to human milk?
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Carnitine is present in both human milk and soy protein formula.
Carnitine is present in both human milk and soy protein formula.
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What is the energy yield of human milk per deciliter?
What is the energy yield of human milk per deciliter?
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Linoleic acid is present in soy protein formula at a concentration of ______ mg/L.
Linoleic acid is present in soy protein formula at a concentration of ______ mg/L.
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Match the following nutrient components with their sources:
Match the following nutrient components with their sources:
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What is a primary characteristic of colostrum?
What is a primary characteristic of colostrum?
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Transitional milk has a lower protein content than mature human milk.
Transitional milk has a lower protein content than mature human milk.
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What is the average pH range of mature human milk?
What is the average pH range of mature human milk?
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Colostrum contains a high concentration of __________, which is crucial for the infant's immune system.
Colostrum contains a high concentration of __________, which is crucial for the infant's immune system.
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Which of these nutrients is present in higher concentration in human mature milk than in cow's milk?
Which of these nutrients is present in higher concentration in human mature milk than in cow's milk?
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What percentage of total calories in human milk comes from fats?
What percentage of total calories in human milk comes from fats?
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Breast milk provides the same protein content as cow's milk.
Breast milk provides the same protein content as cow's milk.
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What is the primary fat content in human milk per deciliter?
What is the primary fat content in human milk per deciliter?
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The calcium content in human milk is higher than in cow's milk.
The calcium content in human milk is higher than in cow's milk.
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Human milk contains _____ essential fatty acids compared to cow’s milk.
Human milk contains _____ essential fatty acids compared to cow’s milk.
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Match the vitamins found in human milk with their content compared to cow's milk:
Match the vitamins found in human milk with their content compared to cow's milk:
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Which vitamin is significantly higher in human milk compared to cow’s milk?
Which vitamin is significantly higher in human milk compared to cow’s milk?
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The iron content in human milk is higher than that in evaporated milk.
The iron content in human milk is higher than that in evaporated milk.
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What is the sodium content in cow's milk per 100 ml?
What is the sodium content in cow's milk per 100 ml?
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Which vitamin is found in significantly higher amounts in evaporated milk compared to human milk?
Which vitamin is found in significantly higher amounts in evaporated milk compared to human milk?
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The main type of carbohydrate found in sweetened condensed milk is lactose.
The main type of carbohydrate found in sweetened condensed milk is lactose.
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What is the protein content in human milk per deciliter?
What is the protein content in human milk per deciliter?
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In humanized milk, the fat content is primarily derived from __________.
In humanized milk, the fat content is primarily derived from __________.
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Match the following types of formulas with their intended purposes:
Match the following types of formulas with their intended purposes:
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What is the predominant fat source in non-premium formula?
What is the predominant fat source in non-premium formula?
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Which of the following is a long-term benefit of breastfeeding for infants?
Which of the following is a long-term benefit of breastfeeding for infants?
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The protein content in non-premium formula is generally lower than that in human milk.
The protein content in non-premium formula is generally lower than that in human milk.
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Breastfeeding has been shown to eliminate the risks of childhood obesity completely.
Breastfeeding has been shown to eliminate the risks of childhood obesity completely.
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How much fat is typically found in human milk per deciliter?
How much fat is typically found in human milk per deciliter?
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Evaporated milk has more __________ vitamins than human milk.
Evaporated milk has more __________ vitamins than human milk.
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What is one potential neurodevelopmental benefit of breastfeeding?
What is one potential neurodevelopmental benefit of breastfeeding?
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Match the following vitamins with their concentrations in human milk and evaporated milk:
Match the following vitamins with their concentrations in human milk and evaporated milk:
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Breastfeeding offers a contraceptive effect known as __________ amenorrhea.
Breastfeeding offers a contraceptive effect known as __________ amenorrhea.
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Match the benefits of breastfeeding to their descriptions:
Match the benefits of breastfeeding to their descriptions:
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Which of the following chronic illnesses is associated with longer durations of breastfeeding?
Which of the following chronic illnesses is associated with longer durations of breastfeeding?
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What is one long-term benefit of breastfeeding for mothers?
What is one long-term benefit of breastfeeding for mothers?
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What is one of the short-term benefits of breastfeeding for infants?
What is one of the short-term benefits of breastfeeding for infants?
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Which of the following is NOT an advantage of breastfeeding?
Which of the following is NOT an advantage of breastfeeding?
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Breastfeeding has no impact on reducing the risk of childhood mortality.
Breastfeeding has no impact on reducing the risk of childhood mortality.
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Breast milk contains high levels of immunoglobulin IgM.
Breast milk contains high levels of immunoglobulin IgM.
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Name one growth factor present in breast milk.
Name one growth factor present in breast milk.
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Name one chronic illness related to the duration of breastfeeding.
Name one chronic illness related to the duration of breastfeeding.
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Breast milk promotes greater __________ stability in late preterm infants.
Breast milk promotes greater __________ stability in late preterm infants.
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Breastfeeding helps reduce the risk of developing __________ in preterm infants.
Breastfeeding helps reduce the risk of developing __________ in preterm infants.
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Match the following components of breast milk with their functions:
Match the following components of breast milk with their functions:
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Match the following benefits of breastfeeding to their respective categories:
Match the following benefits of breastfeeding to their respective categories:
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What type of fatty acids are found in breast milk?
What type of fatty acids are found in breast milk?
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Which component is NOT found in human milk that contributes to its anti-infective properties?
Which component is NOT found in human milk that contributes to its anti-infective properties?
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The analgesic effect is a short-term benefit of breastfeeding.
The analgesic effect is a short-term benefit of breastfeeding.
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Higher intestinal lactase activity is observed in breastfed infants.
Higher intestinal lactase activity is observed in breastfed infants.
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What is the effect of early skin-to-skin contact between mothers and newborns?
What is the effect of early skin-to-skin contact between mothers and newborns?
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What is one property of colostrum that contributes to its health benefits for infants?
What is one property of colostrum that contributes to its health benefits for infants?
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The substance that plays a role in reducing the risk of upper respiratory infections in breastfed infants is __________.
The substance that plays a role in reducing the risk of upper respiratory infections in breastfed infants is __________.
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Breast milk helps lower rates of illnesses such as gastroenteritis and ________ tract infections.
Breast milk helps lower rates of illnesses such as gastroenteritis and ________ tract infections.
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Which of the following is a function of free amino acids found in breast milk?
Which of the following is a function of free amino acids found in breast milk?
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Match the following properties of breast milk with their functions:
Match the following properties of breast milk with their functions:
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Study Notes
Breastfeeding Overview
- Breast milk is nutritionally superior to cow's milk for infants
- Lactation physiology is a complex process involving many hormones
- Different stages of milk production (colostrum, transitional, mature) exhibit distinct compositions
- Key differences in the composition of human milk, cow's milk, and various formulas are presented in various tables.
- Breast milk is a living, biological fluid with antimicrobial properties (immunoglobulins IgA and IgG).
- Several factors (e.g., hormones, maternal diet) influence breast milk composition.
Objectives of Study
- Students should be able to explain the physiology of lactation
- Differentiate between colostrum, transitional, and mature human milk
- Analyze the quantitative and qualitative properties of breast milk and cow's milk and commercial formulas
- List the advantages of breast milk over cow's milk, encompassing economic and societal benefits.
Milk Types
- Breast milk, evaporated milk, condensed milk, humanized milk, cow's milk-based, soy-based, goat's milk-based, hypoallergenic
Hormones During Pregnancy
- Human chorionic gonadotropin (hCG) levels rise dramatically during the first trimester, then plateau
- Placental lactogen, cortisol, progesterone, estradiol and prolactin levels show noticeable increases over time, depending on the stage of pregnancy
Hormonal Control of Lactation
- Reproductive hormones (estrogen, progesterone) influence mammary gland development and proliferation during pregnancy
- Prolactin, oxytocin, and other hormones regulate milk synthesis and ejection during lactation
- Various hormones influence mammary phases and lactation in different ways; some acting directly on the mammary glands and others indirectly via metabolic coordination.
- Hormones like cortisol, somatomedin-C, insulin-like growth factors (IGFs), insulin, and thyroid hormones have roles in milk production and infant development.
- Mothers who have experienced preterm labor may exhibit lower levels of certain milk hormones or immune factors.
Let-Down Reflex
- Infant sucking triggers sensory receptors
- Hypothalamus releases oxytocin, stored in the posterior pituitary
- Myoepithelial bands contract, ejecting milk
- Epinephrine and norepinephrine can block the let-down reflex
Colostrum
- Secreted from the first 5 days after giving birth (first sucking)
- Deep yellow in color
- Alkaline pH (7.7)
- Specific gravity 1.040 – 1.060
- 10-40 ml/day.
- Rich in antibodies (e.g., antibodies to E. coli).
- Contains high amounts of immunoglobulins (especially sIgA).
- Higher concentration of various proteins than later milk stages .
Colostrum - Nutrient Composition
- Lower lactose and fat content compared to later milk stages
- Higher protein and immunoglobulins (especially sIgA), making up 95% of the proteins.
- Richer in vitamin A, minerals (such as Na+, K+, Fe), and trace elements.
- Contains higher numbers of macrophages for phagocytosis (cell engulfment).
- Contains antibodies to E. coli, lysozyme, anti-staphylococcal factor, lactoperoxidase, and bile salt-stimulated lipase
- Has productive lipid byproducts, human milk oligosaccharides
Transitional Milk
- Produced from approximately days 4 to 10 after delivery
- Fats, lactose, and B vitamins gradually increase
- Phosphorus levels higher than in either colostrum or mature milk
Human Mature Milk
- Secreted beyond day 10 postpartum
- Bluish, watery appearance with pH 6.8 to 7.4 (avg. 7)
- Specific gravity 1.026 – 1.036 (avg. 1.031)
- High levels of fats, lactose, and most B vitamins
- Lower proteins, immunoglobulins, minerals, and fat-soluble vitamins
Milk Composition
- Extensive tables comparing nutrient composition between human mature milk, cow's milk, and various formulas.
- Includes calories, fat, protein, lactose, ash, calcium, phosphorus, sodium, potassium, chloride, iron, and vitamins (A, D, E, K, and water-soluble vitamins)
Lactose: Advantages
- Aids Ca+2 and Mg+2 intestinal absorption
- Promotes intestinal bacteria growth, helping lower pH and inhibit pathogen growth
- Promotes fermentative stool flora
- Has a lower sweetness in comparison to sugar
Oligosaccharides/ Complex Carbohydrates
- Small amounts of N2-containing complex carbohydrates (N-acetylglucosamine, sialic acid-containing oligosaccharides, and polysaccharides)
- Promote Bifidobacteria and Lactobacillus growth (beneficial microbes)
- Inhibit harmful GIT pathogens
Protein Nitrogen Fraction
- Protein concentration differs between human and cow's milk
- Human milk protein is primarily whey (60%) unlike cow's milk, which is more casein-based (82%)
Composition of Protein Nitrogen
- Detailed tables showing the concentration of various proteins (α-lactalbumin, lactoferrin, β-lactoglobulin, lysozyme, serum albumin, IgA (sIgA), IgG, IgM) in human milk and cow's milk
Essential Amino Acids
- Lists the concentration of essential amino acids in human milk and cow's milk
Non-Essential Amino Acids
- Lists the concentration of nonessential amino acids in human milk and cow's milk
Fats
- Major energy source for the infant
- Crucial for CNS myelination
- Most variable component of breast milk, impacted by maternal diet (diurnal variation)
Fatty Acid Profile
- Summarizes types of fatty acids in human and cow's milk (saturated, unsaturated, and essential fatty acids)
Minerals
- Compares calcium, phosphorus, sodium, potassium, and chloride content in human and cow's milk
Iron
- Iron content and absorption rates are compared for human milk and cow's milk. Note on iron absorption differences
Vitamins (Fat-Soluble and Water-Soluble)
- Presents the levels of vitamins A, D, E, K, and water-soluble vitamins in human and cow's milk.
Evaporated Milk
- Cow's milk is evaporated at 55-60°C reducing volume to 50%.
- Homogenized and autoclaved
- Pasteurization causes protein quality reduction.
Composition of Human Milk vs. Evaporated Milk
- Compares various components (protein, fat, lactose, calcium, etc.) between human milk and evaporated milk
Sweetened Condensed Milk
- Manufacturing processes involve evaporation, concentration, and sometimes addition of sugar
Composition of Human Milk vs. Condensed Milk
- Compares various components (protein, fat, lactose, various carbohydrates) between human milk and sweetened condensed milk
Humanized Milk
- Summary of humanized milk information, including characteristics
Non-premium Formula
- Discussion of formula characteristics, including protein source composition, compared to human milk; nutritional considerations
Premium Formula
- Intended for healthy infants, composition, and cost compared to human milk
High-Protein Formulas
- Details about high protein formula use after 6 months, rapid growth needs, and composition comparison including protein, fat, and carbs; and comparison to human milk.
Premature Formula
- Use for premature infants and composition comparison to human milk; note on possible enrichment with Vitamins (esp. Vitamin D) in premature formulas. (Composition factors: energy, protein, fat, carbohydrates, minerals, vitamins).
Soy Protein Formulas
- Description with soy protein source, suitability for infants with cow's milk allergy or lactose intolerance, and composition comparison including protein, fat, and carbohydrate content.
Goat's Milk Formula
- Discussion of goat milk formulas and suitability for infants with cow's milk allergy, lactose predominance, and reduced ẞ-lactoglobulin
- Composition comparison.
Goat's Milk Formula Discussion
- Features including intended use for infants with cow's milk/soy allergies, lactose dominance, reduced B-lactoglobulin, Ca+2, protein, and ash content, and cost
Hypoallergenic Formula
- Discussion of hypoallergenic formulas for infants with family history or allergy or those with allergies to proteins; risk reduction of allergies in infants and children, and composition comparison including protein, fat, and carbohydrate content.
Composition of Human Milk vs. Hypoallergenic Formula
- Contrasts of components (energy, protein, fat, CHO, minerals) between human milk and hypoallergenic formula.
Summary of Modifications and Enrichments of Commercial Milk Formulas
- Summary of modifications and enrichments, use of vegetable oils (condensed), lactose-free formulas, soy-based, CHO blends, and other aspects (including added nutrients) and the nutritional effect of the modifications.
Advantages of Breastfeeding
- Both short-term and long-term benefits for mothers and babies are detailed, encompassing aspects in various stages. Including immune system benefits; prevention of acute and chronic illnesses; neurodevelopment; auditory function; behavioral issues; and metabolic processes. - Includes factors such as skin-to-skin contact; improved bonding between mothers and babies; immunity; various protein and hormone effects, and possible protection against some illnesses. (Note on the evidence for benefits of breastfeeding and the associated limitations)
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Description
Test your knowledge on the differences between colostrum and mature human milk. This quiz covers key characteristics, benefits of breastfeeding, and important components in breast milk. Explore essential facts to deepen your understanding of lactation.