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Breast Pathology II: Breast Cancer and Disorders

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20 Questions

What percentage of general cancer cases are breast cancer cases in the US?

30%

What is the most common non-skin cancer in women?

Breast cancer

At what age does breast cancer rarely occur?

Below 25 years

What is a predisposing factor for breast cancer?

Diet high in animal fat

What is the relative risk for breast cancer with atypical hyperplasia?

RR = 2.1 - 4.0

What is a high-risk factor for breast cancer?

Advanced age (>65 years)

What is a risk factor for breast cancer in postmenopausal women?

High endogenous estrogen level

What is a risk factor for breast cancer in women with a family history?

One first-degree relative with breast cancer

What percentage of breast tissue is considered dense?

> 50%

What is a risk factor for breast cancer in men?

Inherited genetic mutations

What is the first site of metastasis for breast cancer?

Axillary lymph nodes

What is the most common type of invasive breast cancer?

Invasive ductal carcinoma

What is the characteristic of lobular carcinoma in situ (LCIS)?

Has discohesive growth

What is the purpose of sentinel node biopsy?

To detect axillary lymph node metastases

What is the risk factor for invasive carcinoma in both breasts?

Lobular carcinoma in situ

What is the genetic mutation associated with male breast cancer?

BRCA2

What is the mammographic feature of ductal carcinoma in situ?

Microcalcifications

What is the prognosis of inflammatory carcinoma?

Poor

What is the function of the HER2 gene?

Human epidermal growth factor receptor

What is the risk factor for breast cancer in women under 40?

Triple negative tumors

Test your knowledge of breast disorders, including breast cancer, its incidence, and predisposing factors. Learn about the demographics affected and the risks associated with this common non-skin cancer in women.

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