Breast Tumors and Cancer Pathology

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20 Questions

Which of the following is the commonest benign tumor of the breast?

Fibroadenoma

What is the characteristic feature of fibroadenoma when observed grossly?

Solitary, capsulated and freely mobile mass

What is the main difference between fibroadenoma and phyllodes tumor?

Stroma is hypercellular in fibroadenoma but not in phyllodes tumor

Which of the following breast tumors is related to increased estrogen levels?

Fibroadenoma

What are the microscopical features of fibroadenoma?

Proliferated ducts and acini lined by single layer of cuboidal epithelium

What is the most common type of breast carcinoma?

Ductal carcinoma

Which gene mutation is associated with hereditary breast cancer?

BRCA1 and BRCA2

What is the characteristic feature of duct papilloma?

Dilated duct with papillae filled with fibrovascular core

What is the peak age incidence of breast carcinoma?

40-60 years of age

Which type of breast carcinoma produces a small breast lump with bloody nipple discharge?

Intraductal carcinoma DCIS

Which condition may be mistaken for mammary carcinoma due to the presence of granulation tissue and foam histiocytes?

Fat necrosis

What is the most common complication associated with epitheliosis in Mammary Cystic Hyperplasia?

Atypical epitheliosis

Which breast lesion is characterized by a nodular ill-defined mass with grayish white cut section and multiple cysts on cut section?

Mammary Cystic Hyperplasia

Which type of breast mass may present with a small breast lump and bloody nipple discharge?

Malignant tumors

What is the main microscopic lesion seen in Mammary Cystic Hyperplasia?

Adenosis

What is the characteristic pathological feature of acute mastitis?

Swollen and congested breast with formation of breast abscess

What is the main pathological feature of chronic mastitis?

Extensive fibrosis

What is the defining feature of mammary duct ectasia?

Ductal dilatations with inspissated secretions

What causes the formation of a firm, tender, white mass with dilated ducts filled with cheesy material in the breast?

Elevated prolactin levels

What is the most common cause of acute suppurative inflammation in the breast during lactation?

Staphylococcus aureus infection

This quiz covers the classification and identification of benign breast tumors such as fibroadenoma, duct papilloma, and phylloids tumor, as well as the predisposing factors and pathological features of breast cancer including ductal carcinoma in situ, invasive ductal carcinoma, and lobular carcinoma.

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