Breast Anatomy and Biopsy Techniques Quiz
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Questions and Answers

What is a significant limitation of fine needle aspiration (FNA)?

  • It does not provide any tumor markers.
  • It cannot distinguish between insitu and invasive cancer. (correct)
  • It requires an incision.
  • It is expensive and time-consuming.

Which biopsy technique is performed under local anesthesia and uses a large-diameter needle?

  • Core needle biopsy (correct)
  • True cut biopsy
  • Fine needle aspiration
  • Incisional biopsy

What is the main advantage of true cut biopsy over fine needle aspiration?

  • It is faster to perform.
  • It requires less skill from the operator.
  • It is less painful for the patient.
  • It can provide tumor marker results. (correct)

What is the main purpose of the triple assessment in breast problems?

<p>To enhance the accuracy of breast cancer diagnosis. (D)</p> Signup and view all the answers

Which imaging modality is considered the best practice for breast screening in a 45-year-old female?

<p>Mammogram (C)</p> Signup and view all the answers

What is the accuracy rate of the triple assessment for breast cancer diagnosis?

<p>99.9% (D)</p> Signup and view all the answers

Which embryonic tissue is the breast originally derived from?

<p>Ectoderm (D)</p> Signup and view all the answers

What is the purpose of Sappey's muscle in the breast?

<p>Causes nipple erection (D)</p> Signup and view all the answers

Which of the following structures primarily anchors the lobes of the breast?

<p>Suspensory ligament of Cooper (D)</p> Signup and view all the answers

What anatomical feature does the breast extend from superiorly to inferiorly?

<p>2nd to 6th intercostal space (B)</p> Signup and view all the answers

What type of tissue primarily decreases in the breast as menopause approaches?

<p>Glandular tissue (B)</p> Signup and view all the answers

Which arteries are primarily responsible for supplying the lateral part of the breast?

<p>Branches of the axillary artery (C)</p> Signup and view all the answers

What are supernumerary nipples referred to as?

<p>Polythelia (D)</p> Signup and view all the answers

What role do Montgomery glands play in the breast?

<p>Lubricate during lactation (D)</p> Signup and view all the answers

The areolar epithelium contains numerous glands during which phase of life?

<p>Pregnancy (B)</p> Signup and view all the answers

What primarily supplies the medial part of the breast?

<p>Medial mammary arteries (D)</p> Signup and view all the answers

Which drainage route accounts for the majority of lymphatic drainage from the breast?

<p>Axillary lymph nodes (D)</p> Signup and view all the answers

How many groups are the axillary lymph nodes arranged into?

<p>5 groups (B)</p> Signup and view all the answers

Which imaging technique is considered the gold standard for evaluating patients with breast implants?

<p>MRI (B)</p> Signup and view all the answers

What is the radiation dose of mammography per film?

<p>1 mGy (A)</p> Signup and view all the answers

What percentage of lymphatic drainage from the breast passes to internal mammary lymph nodes?

<p>20% (C)</p> Signup and view all the answers

Which group of axillary lymph nodes is located at the apex of the axilla?

<p>Apical group (D)</p> Signup and view all the answers

Which investigation is particularly useful for young females with dense breast tissue?

<p>Ultrasound (A)</p> Signup and view all the answers

What lymph nodes do the lymphatic vessels accompany to drain from the breast?

<p>Major blood vessels (D)</p> Signup and view all the answers

Which surgical classification group includes lymph nodes deep to pectoralis minor?

<p>Central group (C)</p> Signup and view all the answers

Flashcards

What is the breast's origin?

The breast is primarily a modified sweat gland developed from the embryonic ectoderm.

Where is the mammary line located?

The mammary line extends from the armpit (axilla) to the groin (inguinal region), marking the potential location of breast tissue development.

What are accessory breast tissues?

Accessory breast tissue can appear anywhere along the mammary line, a result of incomplete regression of embryonic tissue.

Where is the breast located?

The breast sits within the superficial fascia of the anterior chest wall, extending from the 2nd to 6th intercostal spaces, and from the lateral border of the sternum to the mid-axillary line.

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Where does breast tissue extend to?

The breast tissue extends into the anterior axillary fold, important for surgeons to consider during mastectomy.

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What are the main components of the breast?

The breast is composed of 15-20 lobes of glandular tissue responsible for milk production, supported by fibrous connective tissue (Cooper's ligaments), adipose tissue, blood vessels, nerves, and lymphatics.

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Where is adipose tissue located in the breast?

Adipose tissue resides within the parenchyma between the lobes, contributing to the breast's size and shape.

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What causes nipple erection and retraction?

The areola and nipple contain involuntary muscle fibers that contract for nipple erection (Sappeys muscle) and retraction (Myerholts muscle).

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What are the functions of glands in the areola?

The areola is covered with sweat glands and sebaceous glands (Montgomery glands) which enlarge during pregnancy and lubricate the nipple during lactation.

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Fine Needle Aspiration (FNA)

A minimally invasive procedure that uses a thin needle to extract cells from a suspicious area. It's quick, cheap, and doesn't require a cut, but it cannot tell the difference between non-invasive and invasive cancer or check for certain breast cancer markers.

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True Cut Biopsy

A type of biopsy that removes a small piece of tissue for examination. It's more in-depth than FNA, can distinguish between types of cancer, and can be used to check for specific breast cancer markers.

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Core Needle Biopsy

A procedure that utilizes a larger needle to extract a core of tissue for examination. It's performed under local anesthesia and image guidance, and is commonly used for breast tissue.

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Triple Assessment

A comprehensive approach to diagnosing breast problems involving 3 key components: physical examination, imaging (mammography and ultrasound), and FNAC. It's more accurate than any single component alone.

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Breast Ultrasound

An imaging technique that uses sound waves to create images of the breast. It's especially useful for detecting abnormalities in dense breast tissue.

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Mammogram

The most common and effective imaging technique for screening for breast cancer in women over 40. It uses low-dose X-rays to detect subtle changes in breast tissue.

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Breast Blood Supply

The medial mammary arteries, branches of the internal thoracic artery, supply blood to the medial part of the breast. They are assisted by perforating branches from the second, third, and fourth intercostal arteries, contributing to the overall blood supply of the breast.

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Breast Venous Drainage

Breast veins follow the same path as the arteries, draining into the axillary, internal thoracic, and second to fourth intercostal veins.

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Breast Lymphatic Drainage

The complex network of lymphatic vessels in the breast plays a crucial role in draining fluid and potentially cancer cells. Contrary to previous belief, lymphatic plexuses are not the primary route, but instead, lymphatic vessels accompany major blood vessels to reach the following lymph nodes.

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Axillary Lymph Node Drainage (Majority)

75% of lymphatic drainage from the breast flows to the axillary lymph nodes, primarily to the pectoralis, central, and apical groups.

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Internal Mammary Lymph Node Drainage

20% of lymphatic drainage from the breast reaches the internal mammary lymph nodes.

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Other Breast Lymph Node Drainage

5% of breast lymphatic drainage flows to supraclavicular, infraclavicular, subscapular, and intercostal lymph nodes.

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Axillary Lymph Node Groups

The axillary lymph nodes are grouped into five main categories: Anterior (pectoral), Posterior (subscapular), Lateral (humeral), Central, and Apical.

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Axillary Lymph Node Surgical Classification

The surgical classification of axillary lymph nodes divides them into three levels:

  1. Above the pectoralis minor: Apical and infraclavicular nodes.
  2. Deep to the pectoralis minor: Central group.
  3. Below the pectoralis minor: Anterior, posterior, and lateral groups.
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Mammography for Breast Imaging

Mammography is a low-voltage, high-amperage X-ray technique specifically designed for soft tissue imaging. It uses a relatively safe dose of radiation (1mGy per film) to detect breast abnormalities.

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Ultrasound for Breast Imaging

Ultrasound is particularly useful in young women with dense breasts where mammography may be challenging to interpret. It also aids in differentiating cysts from solid breast lesions.

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Study Notes

Breast Anatomy

  • The breast is a modified sweat gland, originating from embryonic ectoderm.
  • It follows a milk line, found between the axilla and inguinal region.
  • Accessory breast tissues can be found along the milk line.
  • Located in the superficial fascia of the anterior chest wall.

Breast Structure

  • The breast comprises 15-20 lobes of tubulo-alveolar glandular tissue.
  • Fibrous connective tissue (Cooper's ligaments) supports the lobes and provides structure.
  • Adipose tissue occupies spaces between lobes, giving breasts their shape and cushioning them.

Breast Blood Supply

  • The breast receives blood from three main sources: the branches of the axillary artery, including superior thoracic, thoracoacromial, lateral thoracic, and subscapular arteries.
  • The internal thoracic artery also supplies blood, particularly to the medial portion of the breast, via medial mammary arteries.
  • Perforating branches of intercostal arteries also supply the breast.
  • Venous drainage follows the arterial supply, with vessels draining into the axillary, internal thoracic, and intercostal veins.

Breast Lymphatic Drainage

  • Lymphatic drainage from the breast primarily goes to the axillary lymph nodes.
  • Approximately 75% drains to the axillary nodes (pectoralis, central, and apical groups).
  • About 20% drains to the internal mammary lymph nodes.
  • A small percentage (5%) drains to supraclavicular, infraclavicular, subscapular, and intercostal lymph nodes.
  • Axillary lymph nodes are grouped into anterior (pectoral), posterior (subscapular), lateral (humeral), central, and apical groups.

Breast Investigation

  • Mammography: A low-voltage, high-amperage X-ray that is useful for assessing the breast. The radiation dose is low, making it safe to use repeatedly.
  • Ultrasound: Particularly useful for young women with dense breasts or when mammography is not effective to distinguish between cysts and solid lesions.
  • MRI: Useful for distinguishing scar tissue from recurrence in patients who have undergone breast surgery, particularly after radiation therapy. Also useful for patients with breast implants or for high-risk patients and for evaluating the axilla after breast cancer treatment.

Breast Investigations (continued)

  • Fine Needle Aspiration (FNA): A rapid, inexpensive procedure that is a helpful initial diagnostic tool. However, it cannot distinguish between in-situ and invasive cancers, and does not provide tumor markers.
  • True-Cut Biopsy: Also does not require incision, it is examined by a cytopathologist and it allows obtaining tumor markers; helping the physician distinguish invasive or non-invasive cancers.
  • Core Needle Biopsy: Performed under local anesthesia, using a large-core biopsy device.
  • Triple Assessment: A process combining physical examination, imaging (mammography and ultrasound), with fine-needle aspiration cytology (FNAC). It has a high diagnostic accuracy reaching 99.9%.

Additional Information

  • The breast is mainly composed of glandular (milk-producing) and fatty tissue. The ratio of these varies between individuals and can be heavily influenced by the hormone estrogen.
  • Areola and nipple contain involuntary muscles that cause nipple erection and retraction. The areolar epithelium also contains Montgomery glands, which produce lubrication during lactation.

Question

  • A 45-year-old woman wants to undergo a breast imaging exam. What is the best imaging to use?
  • Mammogram is generally the best option for women in this age group.

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Description

Test your knowledge on breast anatomy, biopsy techniques, and assessment methods related to breast problems. This quiz covers significant concepts such as the advantages of true cut biopsy and the purpose of the triple assessment. Perfect for students in medical or nursing fields.

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