Breast Anatomy

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Questions and Answers

Where does lymph from the parasternal nodes ultimately drain into?

  • Subclavian vein
  • Right lymphatic duct (correct)
  • Thoracic duct
  • Bronchomediastinal trunks

Which nerves supply the breast?

  • Thoracodorsal nerves
  • Anterior and lateral cutaneous branches of the fourth to sixth intercostal nerves (correct)
  • Vagus nerves
  • Phrenic nerves

How can carcinoma of the breast spread?

  • Via arteries
  • Via bones
  • Via muscles
  • Via lymphatics and veins (correct)

What is the term for the thickened, leatherlike appearance of the skin in breast cancer?

<p>Peau d'orange sign (C)</p> Signup and view all the answers

What is the term for the edema, or excess fluid in the subcutaneous tissue, that can occur in breast cancer?

<p>Lymphedema (A)</p> Signup and view all the answers

What is the space between the breast and the deep pectoral fascia filled with?

<p>Loose connective tissue and a small amount of fat (A)</p> Signup and view all the answers

Which of the following arteries is NOT a contributor to the arterial supply of the breast?

<p>Bronchial artery (C)</p> Signup and view all the answers

What is the function of the suspensory ligaments of Cooper?

<p>To attach the mammary glands to the dermis (C)</p> Signup and view all the answers

What is the anatomical term for the circular pigmented area surrounding the nipple?

<p>Areola (C)</p> Signup and view all the answers

How many lactiferous ducts are present in each breast?

<p>15 to 20 (D)</p> Signup and view all the answers

What is the extension of the mammary gland located in the superolateral quadrant?

<p>Axillary tail (A)</p> Signup and view all the answers

What is the primary source of arterial supply to the breast?

<p>Posterior intercostal arteries (A)</p> Signup and view all the answers

Where does most of the venous drainage of the breast occur?

<p>Axillary vein (B)</p> Signup and view all the answers

Which lymph nodes receive most of the lymphatic drainage from the lateral quadrants of the breast?

<p>Pectoral lymph nodes (A)</p> Signup and view all the answers

Where does lymph from the inferior breast quadrants may drain to?

<p>Abdominal lymph nodes (inferior phrenic nodes) (B)</p> Signup and view all the answers

What is the significance of lymphatic drainage of the breast in relation to cancer?

<p>It is important for the spread of cancer cells (C)</p> Signup and view all the answers

Where does lymph from the axillary nodes drain to?

<p>All of the above (D)</p> Signup and view all the answers

Flashcards

Retromammary space

This separates the breast from the deep pectoral fascia, allowing movement.

Lactiferous ducts

These drain each of the 15-20 lobules of glandular tissue in the breast and open independently on the nipple.

Lactiferous sinus

The dilated section of each lactiferous duct, located just deep to the areola.

Breast Quadrants

This is used for anatomical location and description of pathology in the breast.

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Axillary tail

An extension of the mammary gland located in the superolateral quadrant of the breast.

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Internal thoracic artery

These arteries supply the breast via medial mammary branches

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Axillary artery

These are the arteries that supply the breast via lateral thoracic and thoraco-acromial branches.

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Thoracic aorta

These arteries supply the breast via posterior intercostal branches.

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Axillary vein

This is the main route of venous drainage from the breast.

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Internal thoracic vein

This is an alternative route for venous drainage from the breast.

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Lymphatic drainage

This is crucial in the context of breast cancer metastasis.

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Subareolar lymphatic plexus

A network that receives lymph from the nipple, areola, and lobules.

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Axillary Lymph Nodes

The primary nodes to which >75% of lymph from the breast drains.

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Subclavian lymphatic trunk

Where lymph from axillary nodes ultimately drains.

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Carcinomas of the Breast

Malignant tumors arising from the epithelial cells of the lactiferous ducts.

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Lymphedema

A clinical sign of breast cancer resulting from excess fluid in the subcutaneous tissue.

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Peau d'orange sign

A clinical sign of breast cancer characterized by a thickened, leatherlike appearance of the skin.

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Study Notes

Breast Structure and Function

  • The breast rests on the pectoral fascia covering the pectoralis major (2/3) and the fascia covering the serratus anterior muscle (1/3)
  • The retromammary space (bursa) separates the breast from the deep pectoral fascia, allowing for some degree of movement
  • The breast is composed of 15-20 lobules of glandular tissue, each drained by a lactiferous duct that opens independently on the nipple
  • Each duct has a dilated portion, the lactiferous sinus, just deep to the areola

Breast Quadrants

  • The breast is divided into four quadrants for anatomical location and description of pathology (e.g., cysts and tumors)
  • The axillary tail is an extension of the mammary gland of the superolateral quadrant

Vascularity

  • The arterial supply of the breast is derived from:
    • Medial mammary branches of perforating branches and anterior intercostal branches of the internal thoracic artery
    • Lateral thoracic and thoraco-acromial arteries, branches of the axillary artery
    • Posterior intercostal arteries, branches of the thoracic aorta in the intercostal spaces
  • Venous drainage is mainly to the axillary vein, with some drainage to the internal thoracic vein

Lymphatic Drainage

  • Lymphatic drainage is important for the metastasis (spread) of cancer cells
  • Lymph passes from the nipple, areola, and lobules of the gland to the subareolar lymphatic plexus, and from it:
    • Most lymph (>75%) drains to the axillary lymph nodes (pectoral, humeral, subscapular, central, and apical)
    • Some lymph may drain directly to other axillary nodes, or to interpectoral, deltopectoral, supraclavicular, or inferior deep cervical nodes
  • Lymph from the medial breast quadrants drains to the parasternal lymph nodes or to the opposite breast
  • Lymph from the inferior breast quadrants may pass deeply to abdominal lymph nodes (inferior phrenic nodes)
  • Lymph from the axillary nodes drains to infraclavicular and supraclavicular nodes and from them to the subclavian lymphatic trunk

Carcinoma of Breast

  • Carcinomas of the breast are malignant tumors, usually adenocarcinomas arising from the epithelial cells of the lactiferous ducts
  • Breast cancer can spread via lymphatics (lymphogenic metastasis) and veins
  • Clinical signs include:
    • Lymphedema (edema, excess fluid in the subcutaneous tissue), which may result in deviation of the nipple and a thickened, leatherlike appearance of the skin
    • Peau d'orange sign (orange-peel appearance)

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