BMS161 General Pharmacology Quiz

<p>Can transport molecules against the concentration gradient but requires ATP. (B)</p> Signup and view all the answers

<p>L-dopa absorption into the brain (A)</p> Signup and view all the answers

<p>Understanding the mechanisms of drug action and the body's response to them. (D)</p> Signup and view all the answers

<p>Weak acids are best absorbed in acidic environments. (B)</p> Signup and view all the answers

<p>Larger surface areas increase the rate of drug absorption. (A)</p> Signup and view all the answers

<p>They are critical factors in influencing drug absorption and excretion. (B)</p> Signup and view all the answers

<p>It acts as a transmembrane efflux pump, reducing drug concentration in the bloodstream. (A)</p> Signup and view all the answers

<p>Liver (A)</p> Signup and view all the answers

<p>Patient's emotional state (D)</p> Signup and view all the answers

<p>A specific assessment method involving self-directed group learning. (B)</p> Signup and view all the answers

<p>Pharmacology: A Text for Students and Professionals (3rd edition) (B)</p> Signup and view all the answers

<p>To explain how drugs move through the body from administration to reaching their target sites. (B)</p> Signup and view all the answers

<p>Pharmacokinetics focuses on how drugs are absorbed and eliminated, while pharmacodynamics focuses on how drugs interact with the body. (D)</p> Signup and view all the answers

<p>To treat, diagnose, or prevent diseases (C)</p> Signup and view all the answers

<p>Natural, semi-synthetic, and synthetic sources (B)</p> Signup and view all the answers

<p>Conducted as double-blind studies on large patient groups (D)</p> Signup and view all the answers

<p>To differentiate drug effects from psychological reactions (B)</p> Signup and view all the answers

<p>Focuses on safety and pharmacokinetics with healthy volunteers (B)</p> Signup and view all the answers

<p>They can elicit reactions unrelated to pharmacologic effects (C)</p> Signup and view all the answers

<p>Only psychological treatments (A)</p> Signup and view all the answers

<p>It monitors drug effects after market approval (A)</p> Signup and view all the answers

<p>Decreases drug absorption by pumping drugs out of cells (D)</p> Signup and view all the answers

<p>It determines the ionization of drugs at specific pH levels (D)</p> Signup and view all the answers

<p>Slower gastric emptying can lead to slower absorption (C)</p> Signup and view all the answers

<p>It is the amount of drug that reaches systemic circulation and is available for effect (D)</p> Signup and view all the answers

<p>It is primarily non-ionized in the acidic environment of the stomach (B)</p> Signup and view all the answers

<p>It enhances drug ionization and decreases reabsorption (C)</p> Signup and view all the answers

<p>Un-ionized drugs are lipophilic and can cross membranes for absorption (B)</p> Signup and view all the answers

<p>The presence of food in the gastrointestinal tract (C)</p> Signup and view all the answers

<p>The molecular weight and solubility of the drug (C)</p> Signup and view all the answers

<p>GIT secretions which can result in drug destruction (B)</p> Signup and view all the answers

<p>First-pass effect (C)</p> Signup and view all the answers

<p>Portal circulation, delivering drugs to the liver (D)</p> Signup and view all the answers

<p>Increased blood flow in the portal circulation (B)</p> Signup and view all the answers

<p>Oral and rectal (C)</p> Signup and view all the answers

<p>Intravenous (C)</p> Signup and view all the answers

<p>Subcutaneous (B)</p> Signup and view all the answers

The study of how the body affects a drug, including absorption, distribution, metabolism, and excretion.

The study of how a drug affects the body, including its mechanism of action and therapeutic effects.

The measure of how much of a drug reaches the bloodstream after administration.

The tendency of a drug to dissolve in fat or oil. This affects how easily a drug can cross cell membranes.

The process of a drug being absorbed into the bloodstream from the site of administration.

A protein found in cells that pumps certain drugs out of the body. It affects a drug's serum level.

The pH of the environment can affect a drug's ionization, which can influence its absorption and excretion.

The measure of a drug's tendency to exist in its ionized form. This affects how well a drug can cross cell membranes.

A substance with no pharmacological effect used to control for psychological effects or to compare against an active drug.

A drug that has no inherent medicinal properties, used to control for placebo effects in research studies.

The process by which a drug enters the bloodstream, often through the digestive system, skin, or injection.

The way a drug is transported throughout the body, reaching its intended target and other tissues.

The breakdown of a drug into inactive metabolites, primarily by the liver, making it easier to excrete.

The removal of a drug and its metabolites from the body, usually through urine, feces, or breath.

A technique in which neither the researcher nor the participant knows who is receiving the treatment or the placebo. This minimizes bias and ensures objective results.

A type of study where only the participant is unaware of whether they are receiving the treatment or the placebo, while the researcher knows.

The process by which a dosage form breaks down into smaller particles, allowing for drug release.

The process by which drug particles dissolve into molecules, allowing them to be absorbed.

Factors that influence the breakdown and release of a drug from its dosage form.

The process of a drug being metabolized in the liver, gut wall, or lungs before it reaches systemic circulation.

The metabolism of a drug in the liver before it reaches systemic circulation.

Factors that can affect the drug's absorption and distribution.

The ability of a drug to pass through cell membranes.

The ratio of ionized to unionized drug molecules in a solution.

A drug's tendency to remain bound to proteins in the bloodstream.

The pH at which half of the drug molecules are ionized and half are unionized.

The variation in how drugs are metabolized by different individuals.