BMS149 Lecture 08: Enzymes in Physical Therapy

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What are the general properties of enzymes?

They remain unchanged during a chemical reaction

What is the definition of an enzyme?

A substance that increases the rate of a chemical reaction without being changed itself

What do enzymes end in, according to the text?

-ase

Which suffix is added to the substrate of the reaction to name an enzyme?

-ase

What is a catalyst?

A substance that increases the rate of a chemical reaction without being changed itself

Why are enzymes needed in small amounts?

Because they can be reused multiple times

What is the role of a coenzyme in enzyme function?

To transiently associate with the enzyme

Which class of enzymes catalyze the transfer of electrons or oxygen?

Oxidoreductases

What is the function of hydrolases?

Catalyze the hydrolysis of a substrate by adding H2O

What is the role of ligases in enzymatic reactions?

Catalyze joining of two substrates using ATP as an energy source

What is the function of isomerases?

Catalyze geometric or structural changes within the molecule

How do enzymes accelerate the rate of a reaction?

By providing an alternate reaction pathway with a lower energy of activation

What is the active site of an enzyme?

A pocket formed by folding of the protein, containing amino acid side chains that participate in the reaction

What does the term 'holoenzyme' refer to?

The combination of an apoenzyme and its cofactor/coenzyme

Which term is used to describe a substance that increases the rate of a chemical reaction without being itself changed in the process?

Catalyst

What is the nomenclature rule for naming enzymes?

Adding suffix (ose) to the substrate of the reaction

Which property of enzymes distinguishes them from other biological molecules?

They increase the rate of chemical reactions

What is the primary composition of enzymes?

Proteins only

Which term describes a substance that decreases the rate of a chemical reaction?

Inhibitor

What is the purpose of adding suffix (ase) to a word in enzyme nomenclature?

Describes the action performed by the enzyme

What is the role of oxidoreductases?

Catalyze the transfer of electrons or oxygen

What is the function of isomerases?

Catalyze structural changes within the molecule

What is the function of hydrolases?

Catalyze the hydrolysis of a substrate

What do ligases catalyze in enzymatic reactions?

Catalyze joining of two substrates using ATP as an energy source

What is the active site of an enzyme?

A special pocket or cleft formed by folding of the protein

What is a coenzyme associated with enzymes?

Tightly bound small organic molecule

What is the effect of an enzyme on the energy barrier in a chemical reaction?

Lower the free activation energy

What is a characteristic of lyases in enzymatic reactions?

Catalyze simple splitting of the substrate without adding water

What do transferases catalyze in enzymatic reactions?

The transfer of a chemical group other than hydrogen or oxygen from one substance to another

What is the purpose of cofactors in enzymatic reactions?

To aid enzymes by acting as coenzymes or metal ions

Test your knowledge on enzymes in the context of physical therapy. This quiz covers topics such as enzyme structure, properties, mechanisms of action, factors affecting activity, types of inhibitors, and clinical applications in diagnosing diseases.

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