40 Questions
What is the purpose of performing a crossmatch?
To prevent transfusion reactions and increase in vivo survival of red cells
Why are units negative for the antigen not given to patients with clinically significant antibodies?
To prevent transfusion reactions
What is the purpose of the antibody screen?
To detect the presence of any unexpected antibodies in patient serum
Why is the minor crossmatch not required by AABB since 1976?
Because donated units are already tested for antibodies through antibody paneling
What is the temperature at which clinically significant antibodies are reactive?
37°C
What would be the next step if an antibody screen is positive?
ID antibody and select antigen negative blood
What type of technology is similar to gel technology?
Red cell affinity column technology
What is the purpose of the crossmatch?
To detect antibodies directed against antigens on the donor cell
What type of assay can be used to detect both antigen and antibody?
Solid-Phase Adherence Assays
What would be the next step if the antibody screen is negative and the crossmatch is positive?
ID antibody and select antigen negative blood
What is the primary purpose of performing a crossmatch?
To verify donor cell ABO compatibility and detect most antibodies against donor cells
What is not a limitation of crossmatching?
It can guarantee normal survival of RBCs
What is the significance of detecting antibodies in crossmatching?
To verify the compatibility of the donor and recipient
Under what condition is a complete crossmatch performed?
When an antibody or previous alloantibody is detected
Why are donor cells taken from segments attached to the unit itself?
To prevent contamination of the blood in the bag
What is the primary reason for performing an antibody screen before crossmatching?
To detect clinically significant antibodies in the patient's serum
What is the purpose of the immediate spin phase in crossmatching?
To detect ABO incompatibility between the donor and recipient
What is the significance of a non-reactive result in crossmatching?
The units are compatible for transfusion
What is the requirement for storing samples for donor testing?
Samples must be stored at room temperature for 7 days
What is the purpose of the antiglobulin phase in crossmatching?
To detect clinically significant antibodies to red cell antigens
What is the ultimate objective of the serologic and non-serologic protocols in pretransfusion testing?
To prevent an immune-mediated hemolytic transfusion reaction
What is the primary reason for retaining segments from the released unit in an emergency release?
For possible crossmatching in the future if the patient's sample becomes available
What is the main goal of Medical Technologists in pretransfusion testing?
To ensure safe transfusion of blood units between the donor and the recipient
What may happen to the patient's antibodies in their serum after a large volume blood transfusion?
They become undetectable due to dilution
What is the outcome of properly performed compatibility tests?
Confirmation of ABO compatibility between the component and the recipient
What is the primary purpose of reviewing patient transfusion history during pretransfusion testing?
To detect any existing antibodies that may react with transfused blood
What is the primary purpose of documenting every detail, including names and dates, in an emergency release?
To ensure accountability and protect the medical technologist
What is the most critical step in the pre-analytical phase of pretransfusion testing?
Patient identification
What is the purpose of compatibility testing?
To select blood components that will not cause harm to the recipient
Why is it necessary to perform ABO/Rh typing and antibody screening on the patient's sample once it becomes available?
To ensure the patient's blood type is compatible with the transfused blood
What may be performed as a precaution if more blood is needed in an emergency release?
Crossmatching additional units
What is the primary objective of pretransfusion testing?
To ensure safe transfusion of blood units between the donor and the recipient
What is the purpose of performing an antibody screen during pretransfusion testing?
To detect any existing antibodies that may react with transfused blood
What is the greatest threat to safe transfusion therapy?
Clerical error
What information should be confirmed with the patient during the pretransfusion testing process?
Full patient name and date of birth
What is the primary purpose of crossmatching during pretransfusion testing?
To ensure compatibility between the patient's blood and the donor blood
What is the most common cause of transfusion-related fatalities?
Clerical error
What should be included on the request form and sample during pretransfusion testing?
Patient name, hospital number, physician's name, and date and time of collection
What is the primary responsibility of healthcare professionals during the pretransfusion testing process?
To ensure correct and uneventful transfusion process
What should be done to confirm the patient's identity during pretransfusion testing?
Check the patient's identification bracelet
This quiz covers the importance of crossmatching in blood transfusions, the role of antibodies, and the prevention of transfusion reactions. It explains the difference between major and minor crossmatching and their purposes.
Make Your Own Quizzes and Flashcards
Convert your notes into interactive study material.
Get started for free
