18 Questions
Where does the maturation of B cells primarily occur?
Bone marrow
What is the function of T helper cells (Th) in the immune system?
Promote immune response by activating other immune cells
Which type of cell secretes antibodies?
Plasma cells
Where do T cells undergo maturation and selection processes?
Thymus
What happens during negative selection of T cells in the thymus?
Autoreactive cells undergo apoptotic cell death
Which progenitor gives rise to leukocytes, platelets, erythrocytes, and dendritic cells?
Common myeloid progenitor
What is the function of B lymphocytes?
Secrete antibodies to eliminate antigens
Which marker is specific to Helper T cells?
CD4
What is the role of Cytotoxic T cells?
Kill tumor cells
Which antigen recognition receptor is specific to B lymphocytes?
CD19
What is the nature of the recognized antigen by T lymphocytes?
Peptides only in the form of Peptide+MHC molecules on the surface of APCs
What distinguishes T regulatory cells from Helper T cells and Cytotoxic T cells?
They suppress the immune response
Which cells recognize antigens directly, unlike T lymphocytes?
B lymphocytes
What is the main function of T lymphocytes in antigen recognition?
Recognize a wide variety of antigens
What is the main function of B lymphocytes in the immune system?
Humoral immunity
Which type of lymphocytes do not express either BCR or TCR?
NK cells
What is the antigen receptor on B lymphocytes?
BCR (IgM, IgD)
What is the key difference in antigen recognition between CD4+ and CD8+ T cells?
CD4+ cells recognize peptides + class II MHC, while CD8+ cells recognize peptides + class I MHC.
Test your knowledge on the phenotype markers of blood lymphocytes, such as surface immunoglobulins, CD19, CD21, and class II MHC. Learn about their functions in antibody production and antigen recognition, as well as their role in humoral immunity. Explore the differentiation process into plasma cells and memory B cells.
Make Your Own Quizzes and Flashcards
Convert your notes into interactive study material.
Get started for free
