Podcast
Questions and Answers
Identify the incorrect statement regarding blood groups other than ABO and Rh.
Identify the incorrect statement regarding blood groups other than ABO and Rh.
- They are less well known than the ABO and Rh groups.
- They only affect certain blood types.
- They rarely cause transfusion reactions.
- They frequently cause transfusion reactions. (correct)
Leukocytes spend only a few hours in the bloodstream, then migrate through the walls of the capillaries.
Leukocytes spend only a few hours in the bloodstream, then migrate through the walls of the capillaries.
True (A)
In healthy blood vessels, platelets do not adhere because the smooth endothelium is coated with ______________.
In healthy blood vessels, platelets do not adhere because the smooth endothelium is coated with ______________.
prostacyclin
In addition to the ABO and Rh groups, there are at least 100 other known blood groups, but they rarely cause transfusion reactions.
In addition to the ABO and Rh groups, there are at least 100 other known blood groups, but they rarely cause transfusion reactions.
After tissue repair is completed, factor XII catalyzes the formation of a plasma enzyme called kallikrein, that in turn converts an inactive plasminogen into _________.
After tissue repair is completed, factor XII catalyzes the formation of a plasma enzyme called kallikrein, that in turn converts an inactive plasminogen into _________.
Viscosity and osmolarity will both increase if the amount of ____________ in the blood increases.
Viscosity and osmolarity will both increase if the amount of ____________ in the blood increases.
Hemoglobin concentration and hematocrit are interchangeable terms used to describe the percentage of whole blood composed of RBC.
Hemoglobin concentration and hematocrit are interchangeable terms used to describe the percentage of whole blood composed of RBC.
What are the components of the circulatory system?
What are the components of the circulatory system?
Which of the following is NOT a function of platelets?
Which of the following is NOT a function of platelets?
Blood formation in the bone marrow and lymphatic organs is called, respectively, lymphoid and myeloid hemopoiesis.
Blood formation in the bone marrow and lymphatic organs is called, respectively, lymphoid and myeloid hemopoiesis.
Choose the correct statement regarding the function of platelets.
Choose the correct statement regarding the function of platelets.
The cessation of bleeding is specifically called __________.
The cessation of bleeding is specifically called __________.
Blood clots in the limbs put a patient most at risk for __________.
Blood clots in the limbs put a patient most at risk for __________.
The most important components in the cytoplasm of RBCs are hemoglobin and carbonic anhydrase.
The most important components in the cytoplasm of RBCs are hemoglobin and carbonic anhydrase.
After a wound is sealed, tissue repair is followed by fibrinolysis.
After a wound is sealed, tissue repair is followed by fibrinolysis.
The number of __________ typically increases in response to bacterial infections.
The number of __________ typically increases in response to bacterial infections.
Clotting deficiency can result from thrombocytopenia or hemophilia.
Clotting deficiency can result from thrombocytopenia or hemophilia.
Lymphoid hemopoiesis occurs mainly in the bone marrow.
Lymphoid hemopoiesis occurs mainly in the bone marrow.
Some lymphocytes can survive as long as __________.
Some lymphocytes can survive as long as __________.
A patient is diagnosed with leukocytosis if they have more than __________ WBCs/μL.
A patient is diagnosed with leukocytosis if they have more than __________ WBCs/μL.
Which of the following is not true regarding sickle-cell disease?
Which of the following is not true regarding sickle-cell disease?
The main reason why an individual with type AB, Rh-negative blood cannot donate blood to an individual with type A, Rh-positive blood is because __________.
The main reason why an individual with type AB, Rh-negative blood cannot donate blood to an individual with type A, Rh-positive blood is because __________.
Oxygen and carbon dioxide bind to different parts of hemoglobin.
Oxygen and carbon dioxide bind to different parts of hemoglobin.
Serum is essentially identical to plasma except for the absence of __________.
Serum is essentially identical to plasma except for the absence of __________.
Lymphocytes secrete antibodies, coordinate action of other immune cells, and serve in immune memory.
Lymphocytes secrete antibodies, coordinate action of other immune cells, and serve in immune memory.
Which of the following is not a function of blood?
Which of the following is not a function of blood?
The structural framework of a blood clot is formed by __________.
The structural framework of a blood clot is formed by __________.
Which of the following is not contained in the buffy coat?
Which of the following is not contained in the buffy coat?
Which of these does not prevent the spontaneous formation of a clot?
Which of these does not prevent the spontaneous formation of a clot?
What is the function of thromboplastin in hemostasis?
What is the function of thromboplastin in hemostasis?
Which of the following is most likely to cause anemia?
Which of the following is most likely to cause anemia?
Rh incompatibility between a sensitized Rh+ woman and an Rh- fetus can cause hemolytic disease of the newborn.
Rh incompatibility between a sensitized Rh+ woman and an Rh- fetus can cause hemolytic disease of the newborn.
Which cells aid in the body's defense processes by secreting histamine and heparin?
Which cells aid in the body's defense processes by secreting histamine and heparin?
Erythrocytes transport oxygen and ________.
Erythrocytes transport oxygen and ________.
Hemostasis is the production of formed elements of blood.
Hemostasis is the production of formed elements of blood.
Where in the body are hemopoietic stem cells found?
Where in the body are hemopoietic stem cells found?
A patient is suffering from ketoacidosis caused by an unregulated high protein diet. Which function of the blood has been compromised?
A patient is suffering from ketoacidosis caused by an unregulated high protein diet. Which function of the blood has been compromised?
Why are pregnant Rh- women given an injection of Rh immune globulin?
Why are pregnant Rh- women given an injection of Rh immune globulin?
An individual has type B, Rh-positive blood. The individual has __________ antigen(s) and can produce anti-__________ antibodies.
An individual has type B, Rh-positive blood. The individual has __________ antigen(s) and can produce anti-__________ antibodies.
Leukopoiesis begins with the differentiation of __________.
Leukopoiesis begins with the differentiation of __________.
A deficiency of __________ can cause pernicious anemia.
A deficiency of __________ can cause pernicious anemia.
What are the least abundant of the formed elements?
What are the least abundant of the formed elements?
Which of the following would not lead to polycythemia?
Which of the following would not lead to polycythemia?
What are the most abundant agranulocytes?
What are the most abundant agranulocytes?
The viscosity of blood is due more to the presence of __________ than to any other factor.
The viscosity of blood is due more to the presence of __________ than to any other factor.
Where do most RBCs die?
Where do most RBCs die?
Most oxygen is transported in the blood bound to _________.
Most oxygen is transported in the blood bound to _________.
A normal hematocrit is __________ of the total blood volume.
A normal hematocrit is __________ of the total blood volume.
Correction of hypoxemia is regulated by _________.
Correction of hypoxemia is regulated by _________.
Where are most clotting factors synthesized in the body?
Where are most clotting factors synthesized in the body?
Which of the following is not true of a patient with anemia?
Which of the following is not true of a patient with anemia?
Monocytes differentiate into large phagocytic cells.
Monocytes differentiate into large phagocytic cells.
What is the final product of the breakdown of the organic nonprotein moiety of hemoglobin?
What is the final product of the breakdown of the organic nonprotein moiety of hemoglobin?
Flashcards
Blood groups beyond ABO and Rh
Blood groups beyond ABO and Rh
Blood groups other than ABO and Rh rarely cause transfusion reactions
Leukocyte migration
Leukocyte migration
Leukocytes move quickly out of the bloodstream into tissues.
Neutrophils in infection
Neutrophils in infection
Neutrophils increase when there's a bacterial infection.
Monocyte differentiation
Monocyte differentiation
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Platelet adherence
Platelet adherence
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Platelet function in clotting
Platelet function in clotting
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Hemostasis
Hemostasis
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Factor XII role in clotting
Factor XII role in clotting
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Fibrin in clotting
Fibrin in clotting
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Thromboplastin and clotting
Thromboplastin and clotting
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Components of blood circulatory system
Components of blood circulatory system
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Blood oxygen transport
Blood oxygen transport
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Serum vs. plasma
Serum vs. plasma
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Hemoglobin vs. Hematocrit
Hemoglobin vs. Hematocrit
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RBC destruction sites
RBC destruction sites
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Normal hematocrit range
Normal hematocrit range
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Hemopoiesis location
Hemopoiesis location
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Hemopoietic stem cells
Hemopoietic stem cells
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Blood viscosity source
Blood viscosity source
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Sickle cell disease
Sickle cell disease
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Causes of anemia
Causes of anemia
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Blood viscosity in anemia
Blood viscosity in anemia
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Rh incompatibility
Rh incompatibility
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Rh immune globulin
Rh immune globulin
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Basophil secretions
Basophil secretions
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Lymphocyte roles
Lymphocyte roles
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Blood viscosity factors
Blood viscosity factors
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Hypoxemia correction
Hypoxemia correction
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Liver's role in clotting
Liver's role in clotting
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Most abundant agranulocyte
Most abundant agranulocyte
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Least abundant formed element
Least abundant formed element
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Blood hormone production
Blood hormone production
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Study Notes
Blood Groups and Transfusion Reactions
- Blood groups beyond ABO and Rh typically do not cause transfusion reactions.
- Over 100 known blood groups exist, but transfusion reactions are rare.
Leukocytes and Immune Response
- Leukocytes spend limited time in bloodstream; quickly migrate through capillary walls.
- Neutrophils increase in response to bacterial infections.
- Monocytes differentiate into large phagocytic cells for immune defense.
Platelets and Hemostasis
- Platelets do not adhere to healthy blood vessels due to a smooth endothelium coated with prostacyclin.
- Functions of platelets include secreting procoagulants to promote blood clotting.
- Cessation of bleeding is termed hemostasis.
Clotting Mechanisms
- Factor XII leads to the formation of kallikrein, converting plasminogen to plasmin, which breaks down clots.
- Fibrin polymer forms the structural framework of a blood clot.
- Thromboplastin initiates the extrinsic pathway of coagulation.
Components and Functions of Blood
- Components include heart, blood vessels, and blood.
- Blood transports oxygen bound to heme groups in hemoglobin and some carbon dioxide.
- Serum is plasma without fibrinogen.
Erythrocyte Characteristics
- Hemoglobin concentration and hematocrit are not interchangeable; hematocrit refers specifically to RBC percentage.
- RBCs primarily die in the spleen and liver.
- A normal hematocrit ranges from 37% to 52%.
Hematopoiesis and Blood Formation
- Blood formation in bone marrow and lymphatic organs is termed hemopoiesis.
- Hemopoietic stem cells reside in red bone marrow.
- Blood viscosity is mainly attributed to erythrocyte presence.
Blood Disorders and Conditions
- Sickle-cell disease is incorrectly identified as a malaria cause; it is a genetic condition affecting hemoglobin.
- Anemia can arise from various causes, including renal disease and vitamin B12 deficiency.
- Patients with anemia often experience decreased blood viscosity.
Pregnancy and Blood Compatibility
- Rh incompatibility between sensitized Rh+ mothers and Rh- fetuses can lead to hemolytic disease of the newborn.
- Pregnant Rh- women receive Rh immune globulin to prevent anti-D antibody production.
Other Blood Elements
- Basophils secrete histamine and heparin, aiding defense processes.
- Lymphocytes play roles in antibody secretion and immune memory.
Blood Composition and Health Regulation
- Erythrocytes and plasma protein levels affect blood viscosity and osmolarity.
- Correction of hypoxemia is maintained through a negative feedback loop.
- Most clotting factors are synthesized in the liver.
General Blood Facts
- Lymphocytes are the most abundant agranulocytes.
- Basophils are the least abundant formed elements.
- Blood does not produce plasma hormones; that function is not attributed to blood.
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Description
This quiz covers essential concepts about blood groups beyond ABO and Rh, as well as key facts about leukocytes and their behavior in the bloodstream. Test your knowledge on these important components of the human circulatory system. Suitable for students studying human biology or medical sciences.