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Questions and Answers
Which of the following is a primary function of blood?
Which of the following is a primary function of blood?
What role does blood play in regulating body temperature?
What role does blood play in regulating body temperature?
Which component makes up the highest percentage of blood plasma?
Which component makes up the highest percentage of blood plasma?
What is the approximate percentage of blood volume made up by blood plasma?
What is the approximate percentage of blood volume made up by blood plasma?
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Which of the following electrolytes is found in blood plasma?
Which of the following electrolytes is found in blood plasma?
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Which enzyme initiates the digestion of starch in the mouth?
Which enzyme initiates the digestion of starch in the mouth?
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What is the name given to the mixture of food and gastric secretions in the stomach?
What is the name given to the mixture of food and gastric secretions in the stomach?
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Which organ stores, concentrates, and releases bile?
Which organ stores, concentrates, and releases bile?
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What is the primary function of the large intestine?
What is the primary function of the large intestine?
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Which of the following enzymes is responsible for breaking down proteins into smaller peptides in the stomach?
Which of the following enzymes is responsible for breaking down proteins into smaller peptides in the stomach?
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Which of the following is NOT produced by the pancreas?
Which of the following is NOT produced by the pancreas?
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Which of the following is the function of hydrochloric acid (HCl) in the stomach?
Which of the following is the function of hydrochloric acid (HCl) in the stomach?
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What is the role of bile in digestion?
What is the role of bile in digestion?
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Where does the majority of nutrient absorption take place?
Where does the majority of nutrient absorption take place?
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Which enzyme breaks down fats into glycerol and fatty acids?
Which enzyme breaks down fats into glycerol and fatty acids?
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Which plasma protein group is the smallest and most abundant?
Which plasma protein group is the smallest and most abundant?
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What is the key function of fibrinogen?
What is the key function of fibrinogen?
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Which hormone causes more erythropoietin secretion by the kidney?
Which hormone causes more erythropoietin secretion by the kidney?
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What is the primary function of red blood cells?
What is the primary function of red blood cells?
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Why do red blood cells lack a nucleus?
Why do red blood cells lack a nucleus?
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What metal is at the center of the heme group in hemoglobin?
What metal is at the center of the heme group in hemoglobin?
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Which type of white blood cell is the most abundant?
Which type of white blood cell is the most abundant?
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What is the function of B cells?
What is the function of B cells?
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Which blood type is considered the universal recipient?
Which blood type is considered the universal recipient?
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What is the first phase in response to blood vessel injury?
What is the first phase in response to blood vessel injury?
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What antigens does Type O blood have?
What antigens does Type O blood have?
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What causes greater vasoconstriction?
What causes greater vasoconstriction?
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What happens during hemolysis in an incompatible blood transfusion?
What happens during hemolysis in an incompatible blood transfusion?
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What helps platelets adhere to collagen upon damage to blood vessel endothelium?
What helps platelets adhere to collagen upon damage to blood vessel endothelium?
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What is agglutination?
What is agglutination?
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What limits the platelet plug?
What limits the platelet plug?
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What molecule does hemoglobin transport?
What molecule does hemoglobin transport?
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What causes the biconcave disc shape of red blood cells?
What causes the biconcave disc shape of red blood cells?
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What is the final product of blood clotting?
What is the final product of blood clotting?
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What role do monocytes play in the immune system?
What role do monocytes play in the immune system?
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What is the enzyme responsible for breaking down a clot?
What is the enzyme responsible for breaking down a clot?
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What is the inactive enzyme that is converted to plasmin?
What is the inactive enzyme that is converted to plasmin?
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What do you call smaller fragments that plasmin breaks down?
What do you call smaller fragments that plasmin breaks down?
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What promotes tissue repair?
What promotes tissue repair?
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What do you call a stationary clot within a blood vessel?
What do you call a stationary clot within a blood vessel?
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What removes remaining fragments from a blood clot?
What removes remaining fragments from a blood clot?
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What is the introduction of solid and liquid nurtients into the oral cavity?
What is the introduction of solid and liquid nurtients into the oral cavity?
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What do you call breaking down food into smaller pieces, without changing the chemical compositions?
What do you call breaking down food into smaller pieces, without changing the chemical compositions?
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What is the movement of digested molecules from the GI tract into blood or lymph?
What is the movement of digested molecules from the GI tract into blood or lymph?
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What do you call the removal of undigested food and waste?
What do you call the removal of undigested food and waste?
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Flashcards
Functions of Blood
Functions of Blood
The primary roles of blood include transport, regulation, fluid balance, and protection.
Transport Function
Transport Function
Blood carries oxygen, carbon dioxide, nutrients, hormones, heat, and waste products.
Blood Plasma Composition
Blood Plasma Composition
Blood plasma is about 90-92% water and 8-10% dissolved substances, including electrolytes, nutrients, and waste.
Osmotic Pressure Proteins
Osmotic Pressure Proteins
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Key Blood Proteins
Key Blood Proteins
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Salivary Amylase
Salivary Amylase
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Bolus
Bolus
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Chyme
Chyme
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Duodenum
Duodenum
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Gallbladder
Gallbladder
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Pancreas
Pancreas
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Pepsin
Pepsin
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Small Intestine
Small Intestine
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Bile
Bile
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Large Intestine
Large Intestine
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Albumins
Albumins
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Fibrinogen
Fibrinogen
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Hematocrit
Hematocrit
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Red Blood Cells
Red Blood Cells
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Hemoglobin
Hemoglobin
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Oxygen Transport
Oxygen Transport
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Carbon Dioxide Transport
Carbon Dioxide Transport
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pH Regulation
pH Regulation
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Neutrophils
Neutrophils
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Lymphocytes
Lymphocytes
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Blood Type A
Blood Type A
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Universal Donor
Universal Donor
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Incompatible Transfusion
Incompatible Transfusion
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Agglutination
Agglutination
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Clotting Cascade
Clotting Cascade
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Vascular Spasm
Vascular Spasm
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Platelet Plug Formation
Platelet Plug Formation
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Von Willebrand Factor (VWF)
Von Willebrand Factor (VWF)
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Thromboxane A2
Thromboxane A2
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Coagulation
Coagulation
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Fibrin Mesh
Fibrin Mesh
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Fibrinolysis
Fibrinolysis
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Plasminogen
Plasminogen
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Deep Vein Thrombosis (DVT)
Deep Vein Thrombosis (DVT)
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Pulmonary Embolism (PE)
Pulmonary Embolism (PE)
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Thrombosis
Thrombosis
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Risk Factors for Thrombosis
Risk Factors for Thrombosis
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Compression Therapy
Compression Therapy
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Blood Thinners
Blood Thinners
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Macrophages
Macrophages
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Study Notes
Blood Functions
- Transports formed elements, dissolved molecules, and ions
- Carries oxygen to and carbon dioxide from the lungs
- Transports nutrients, hormones, heat, and waste products (e.g., carbon dioxide, urea)
- Regulates body conditions
- Body temperature: Absorbs heat; releases heat at skin blood vessels.
- Body pH: Absorbs acids and bases; contains chemical buffers (e.g., bicarbonate).
- Fluid balance: Adds water from the GI tract; loses water in urine, skin, and respiration; exchanges fluid with interstitial fluid, maintains osmotic balance with proteins and ions.
- Protects against pathogens: Leukocytes, plasma proteins, and other immune system molecules.
- Protects against blood loss: Platelets and plasma proteins.
Blood Plasma
- Accounts for ~55% of blood volume.
- Liquid component transporting various substances.
- Composition:
- Mostly water (~90-92%)
- Dissolved substances (8-10%): Electrolytes (Na+, K+, Ca2+, Cl-, HCO3-), nutrients, waste products (urea, creatinine, uric acid), hormones, and gases (O2, CO2, N2).
Important Blood Proteins
- Albumins: Smallest and most abundant (58%), exert significant colloid osmotic pressure, and transport lipids, hormones, and ions.
- Fibrinogen: Key protein in blood clotting.
Red Blood Cells (Erythrocytes)
- Small, flexible, biconcave discs.
- Lack nucleus and organelles, packed with hemoglobin.
- Transport oxygen and carbon dioxide.
- Why lack a nucleus?
- More hemoglobin capacity.
- Flexible shape for capillary passage.
- Efficient gas exchange.
- Increased lifespan (120 days) because they don't need to use oxygen internally.
- Hemoglobin:
- Red-pigmented protein.
- Transports oxygen and carbon dioxide (oxygenated/deoxygenated forms).
- Composed of four globins (two alpha, two beta chains), each with a heme group containing iron.
- Oxygen binds to iron.
White Blood Cells (Leukocytes)
- Part of the immune system, defending against infections and abnormal cells.
- Have a nucleus, different types with specific functions:
- Neutrophils: Fight bacterial/fungal infections.
- Lymphocytes: Include B cells (antibodies), and T cells (attack infected/cancerous cells).
- Monocytes: Become macrophages engulfing pathogens and dead cells.
- Eosinophils: Fight parasites and have a role in allergic reactions.
- Basophils: Release histamine in allergic responses.
Blood Types and Compatibility
- Determined by antigens (A, B, Rh) on red blood cells.
- Types: A, B, AB, O.
- Rh factor (+/-)
- Incompatible transfusion causes hemolysis (RBC destruction), agglutination (clumping), leading to serious reactions in the recipient.
- Careful cross-matching is essential before transfusions.
Hemostasis (Blood Clotting)
- Three phases:
- Vascular spasm: Blood vessel constriction, limiting leakage.
- Platelet plug formation: Platelets adhere to exposed collagen fibers, forming a plug.
- Coagulation: Blood transforms from liquid to gel, forming a fibrin mesh.
Clot Breakdown (Fibrinolysis)
- Dissolves clots via plasmin.
- Plasminogen (inactive enzyme) converted to plasmin by activators.
- Fibrin broken down into fragments.
- Removal of fragments by macrophages.
Undesirable Clotting (Thrombosis)
- Thrombus: Stationary clot in a blood vessel.
- Embolus: Clot that travels and blocks vessels.
- Conditions: Deep vein thrombosis (DVT), pulmonary embolism (PE), stroke, heart attack.
- Causes include blood stasis, hypercoagulability, endothelial injury.
- Prevention and treatment: Medications (blood thinners), lifestyle changes, compression therapy.
Digestive System
- Organs (GI tract, accessory organs):
- Mouth, teeth, saliva, esophagus, stomach, small intestine, liver, gallbladder, pancreas, large intestine.
- Processes:
- Ingestion: Food intake.
- Propulsion: Moving food through GI tract.
- Mechanical digestion: Breaking food into smaller pieces.
- Chemical digestion: Breaking down food molecules with enzymes.
- Absorption: Transport of nutrients into blood or lymph.
- Excretion: Removal of undigested material.
- Details for sections above can be found in details given. Function of Bile
Bile is a digestive fluid produced by the liver and stored in the gallbladder. It plays a crucial role in fat digestion and absorption in the small intestine.
Functions of Bile: 1. Emulsification of Fats • Bile contains bile salts that break large fat globules into smaller droplets, increasing the surface area for the enzyme pancreatic lipase to act on. • This process helps digest and absorb dietary fats efficiently. 2. Aids in Fat Absorption • The breakdown of fats by bile and pancreatic lipase produces monoglycerides and free fatty acids, which form micelles (tiny fat droplets surrounded by bile salts). • Micelles help transport fats to the intestinal lining for absorption. 3. Elimination of Waste Products • Bile contains bilirubin, a byproduct of red blood cell breakdown, which gives feces its brown color. • It also helps remove cholesterol and toxins from the body. 4. Alkalinization of Intestinal Contents • Bile is slightly alkaline, helping neutralize stomach acid in the small intestine, creating a suitable pH for pancreatic enzymes to work. 5. Facilitates Vitamin Absorption • Bile aids in the absorption of fat-soluble vitamins (A, D, E, K) by helping dissolve them in micelles for transport across the intestinal lining.
Where is Bile Released? • When fatty food enters the duodenum (first part of the small intestine), the hormone cholecystokinin (CCK) signals the gallbladder to release bile into the bile duct, which then empties into the small intestine.
Would you like more details on bile disorders like gallstones or liver disease?
Hepatic Blood Flow
The liver receives blood from two main sources: 1. Hepatic Artery – Supplies oxygenated blood from the heart (~25% of liver’s blood supply). 2. Hepatic Portal Vein – Supplies nutrient-rich, deoxygenated blood from the digestive organs (~75% of liver’s blood supply).
After processing, blood exits the liver through the hepatic veins into the inferior vena cava, which returns blood to the heart.
Pathway of Hepatic Blood Flow: 1. Hepatic Artery (Oxygenated Blood) • Branches from the celiac trunk (off the aorta). • Delivers oxygen-rich blood to hepatocytes (liver cells). 2. Hepatic Portal Vein (Nutrient-Rich Blood) • Formed by the union of the superior mesenteric vein (from the small intestine) and the splenic vein. • Carries nutrients, toxins, and hormones from the digestive tract for processing in the liver. 3. Liver Sinusoids • Capillary-like structures in the liver where hepatic artery and portal vein blood mix. • Kupffer cells (liver macrophages) remove bacteria and toxins. • Hepatocytes process nutrients, detoxify chemicals, and produce bile. 4. Central Veins → Hepatic Veins → Inferior Vena Cava • Processed blood drains into central veins, which merge into hepatic veins. • Hepatic veins empty into the inferior vena cava, returning blood to the heart.
Functions of Hepatic Blood Flow • Nutrient Processing: Regulates glucose, amino acids, and lipids. • Detoxification: Removes drugs, alcohol, and toxins. • Immune Function: Kupffer cells filter pathogens. • Bile Production: Helps digest fats and remove waste.
Would you like a diagram or details on liver diseases affecting blood flow (e.g., cirrhosis, portal hypertension)?
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Description
Explore the vital roles of blood in transporting elements, regulating body conditions, and protecting against pathogens. This quiz also delves into the composition of blood plasma, which constitutes a significant portion of blood volume and its various dissolved substances.