Blood Functions and Plasma Composition
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Questions and Answers

Which of the following is a primary function of blood?

  • Filtering air for respiration
  • Transporting oxygen and carbon dioxide (correct)
  • Synthesizing hormones
  • Producing digestive enzymes
  • What role does blood play in regulating body temperature?

  • It insulates the body to prevent heat loss.
  • It absorbs heat from body cells and releases it at the skin. (correct)
  • It cools the body by producing sweat.
  • It generates heat through metabolic processes.
  • Which component makes up the highest percentage of blood plasma?

  • Proteins
  • Electrolytes
  • Water (correct)
  • Nutrients
  • What is the approximate percentage of blood volume made up by blood plasma?

    <p>55% (D)</p> Signup and view all the answers

    Which of the following electrolytes is found in blood plasma?

    <p>Sodium (C)</p> Signup and view all the answers

    Which enzyme initiates the digestion of starch in the mouth?

    <p>Salivary amylase (C)</p> Signup and view all the answers

    What is the name given to the mixture of food and gastric secretions in the stomach?

    <p>Chyme (B)</p> Signup and view all the answers

    Which organ stores, concentrates, and releases bile?

    <p>Gallbladder (A)</p> Signup and view all the answers

    What is the primary function of the large intestine?

    <p>Water and electrolyte absorption (C)</p> Signup and view all the answers

    Which of the following enzymes is responsible for breaking down proteins into smaller peptides in the stomach?

    <p>Pepsin (A)</p> Signup and view all the answers

    Which of the following is NOT produced by the pancreas?

    <p>Bile (C)</p> Signup and view all the answers

    Which of the following is the function of hydrochloric acid (HCl) in the stomach?

    <p>Activating pepsin (D)</p> Signup and view all the answers

    What is the role of bile in digestion?

    <p>Emulsifies fats (D)</p> Signup and view all the answers

    Where does the majority of nutrient absorption take place?

    <p>Small intestine (D)</p> Signup and view all the answers

    Which enzyme breaks down fats into glycerol and fatty acids?

    <p>Lipase (B)</p> Signup and view all the answers

    Which plasma protein group is the smallest and most abundant?

    <p>Albumins (D)</p> Signup and view all the answers

    What is the key function of fibrinogen?

    <p>Blood clotting (C)</p> Signup and view all the answers

    Which hormone causes more erythropoietin secretion by the kidney?

    <p>Testosterone (B)</p> Signup and view all the answers

    What is the primary function of red blood cells?

    <p>Transporting oxygen and carbon dioxide (C)</p> Signup and view all the answers

    Why do red blood cells lack a nucleus?

    <p>To increase flexibility and space for hemoglobin (D)</p> Signup and view all the answers

    What metal is at the center of the heme group in hemoglobin?

    <p>Iron (A)</p> Signup and view all the answers

    Which type of white blood cell is the most abundant?

    <p>Neutrophils (D)</p> Signup and view all the answers

    What is the function of B cells?

    <p>Producing antibodies (D)</p> Signup and view all the answers

    Which blood type is considered the universal recipient?

    <p>Type AB (B)</p> Signup and view all the answers

    What is the first phase in response to blood vessel injury?

    <p>Vascular spasm (D)</p> Signup and view all the answers

    What antigens does Type O blood have?

    <p>No A or B antigens (C)</p> Signup and view all the answers

    What causes greater vasoconstriction?

    <p>Major vessel damage (D)</p> Signup and view all the answers

    What happens during hemolysis in an incompatible blood transfusion?

    <p>Red blood cells are destroyed (D)</p> Signup and view all the answers

    What helps platelets adhere to collagen upon damage to blood vessel endothelium?

    <p>Von Willebrand factor (VWF) (A)</p> Signup and view all the answers

    What is agglutination?

    <p>The clumping of blood cells due to antibodies. (B)</p> Signup and view all the answers

    What limits the platelet plug?

    <p>PGI2 (D)</p> Signup and view all the answers

    What molecule does hemoglobin transport?

    <p>Oxygen and carbon dioxide (D)</p> Signup and view all the answers

    What causes the biconcave disc shape of red blood cells?

    <p>Absence of a nucleus and organelles (D)</p> Signup and view all the answers

    What is the final product of blood clotting?

    <p>Fibrin mesh (C)</p> Signup and view all the answers

    What role do monocytes play in the immune system?

    <p>Becoming macrophages and engulfing pathogens (C)</p> Signup and view all the answers

    What is the enzyme responsible for breaking down a clot?

    <p>Plasmin (B)</p> Signup and view all the answers

    What is the inactive enzyme that is converted to plasmin?

    <p>Plasminogen (D)</p> Signup and view all the answers

    What do you call smaller fragments that plasmin breaks down?

    <p>Fibrin degradation products (FDPs) (A)</p> Signup and view all the answers

    What promotes tissue repair?

    <p>Fibrin mesh (B)</p> Signup and view all the answers

    What do you call a stationary clot within a blood vessel?

    <p>Thrombus (B)</p> Signup and view all the answers

    What removes remaining fragments from a blood clot?

    <p>Macrophages (C)</p> Signup and view all the answers

    What is the introduction of solid and liquid nurtients into the oral cavity?

    <p>Ingestion (C)</p> Signup and view all the answers

    What do you call breaking down food into smaller pieces, without changing the chemical compositions?

    <p>Mechanical digestion (D)</p> Signup and view all the answers

    What is the movement of digested molecules from the GI tract into blood or lymph?

    <p>Absorption (C)</p> Signup and view all the answers

    What do you call the removal of undigested food and waste?

    <p>Excretion (A)</p> Signup and view all the answers

    Flashcards

    Functions of Blood

    The primary roles of blood include transport, regulation, fluid balance, and protection.

    Transport Function

    Blood carries oxygen, carbon dioxide, nutrients, hormones, heat, and waste products.

    Blood Plasma Composition

    Blood plasma is about 90-92% water and 8-10% dissolved substances, including electrolytes, nutrients, and waste.

    Osmotic Pressure Proteins

    Proteins like albumin in plasma help maintain osmotic pressure and fluid balance in the blood.

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    Key Blood Proteins

    Important proteins in blood plasma include albumin, fibrinogen, and immunoglobulins for clotting and immunity.

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    Salivary Amylase

    Enzyme in saliva that starts starch digestion.

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    Bolus

    A mass of food formed in the mouth for swallowing.

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    Chyme

    Semi-liquid mixture of food and gastric juices in the stomach.

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    Duodenum

    First part of the small intestine where most digestion occurs.

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    Gallbladder

    Stores and concentrates bile from the liver.

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    Pancreas

    Produces digestive enzymes and hormones like insulin.

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    Pepsin

    Enzyme in the stomach that breaks down proteins.

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    Small Intestine

    Primary site for nutrient absorption and digestion.

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    Bile

    Digestive fluid produced by the liver that emulsifies fats.

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    Large Intestine

    Absorbs water and compacts waste into feces.

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    Albumins

    Smallest and most abundant plasma proteins (58%), crucial for osmotic pressure.

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    Fibrinogen

    Key plasma protein involved in blood clotting process.

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    Hematocrit

    Percentage of blood volume made up of red blood cells.

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    Red Blood Cells

    Small, flexible cells without a nucleus, packed with hemoglobin for gas transport.

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    Hemoglobin

    Red protein in RBCs that transports oxygen and carbon dioxide.

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    Oxygen Transport

    Process where RBCs carry oxygen from lungs to tissues.

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    Carbon Dioxide Transport

    RBCs transport CO2 from tissues to lungs for expulsion.

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    pH Regulation

    RBCs help maintain blood pH by buffering hydrogen ions.

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    Neutrophils

    Most abundant WBCs that fight bacterial and fungal infections.

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    Lymphocytes

    WBCs that include B cells and T cells for antibody production and attack.

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    Blood Type A

    Red blood cells have A antigens and produce anti-B antibodies.

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    Universal Donor

    Blood type O has no A or B antigens and can donate to any type.

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    Incompatible Transfusion

    Occurs when the wrong blood type is given, leading to immune reaction.

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    Agglutination

    Clumping of red blood cells due to antibodies binding to foreign cells.

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    Clotting Cascade

    Series of chemical reactions that lead to blood clot formation.

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    Vascular Spasm

    Constricted blood vessels that limit blood loss after injury.

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    Platelet Plug Formation

    Platelets adhere to exposed collagen, forming a plug at injury sites.

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    Von Willebrand Factor (VWF)

    A protein that helps platelets adhere to damaged blood vessels.

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    Thromboxane A2

    A chemical released by activated platelets that stimulates further platelet aggregation.

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    Coagulation

    The process of blood transforming from liquid to gel, forming a clot.

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    Fibrin Mesh

    A network of fibers that stabilizes a blood clot and prevents excessive bleeding.

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    Fibrinolysis

    The process of breaking down a blood clot after it has fulfilled its function.

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    Plasminogen

    An inactive enzyme incorporated into clots that gets activated to dissolve clots.

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    Deep Vein Thrombosis (DVT)

    A blood clot that forms in deep veins, often of the legs.

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    Pulmonary Embolism (PE)

    A clot that travels to the lungs, blocking blood flow.

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    Thrombosis

    Undesirable clot formation within blood vessels without injury.

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    Risk Factors for Thrombosis

    Conditions that increase the likelihood of unwanted blood clots.

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    Compression Therapy

    Use of compression stockings to improve leg circulation and prevent clots.

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    Blood Thinners

    Medications that reduce blood clotting risk, like heparin and warfarin.

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    Macrophages

    Immune cells that help clear out clot fragments after fibrinolysis.

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    Study Notes

    Blood Functions

    • Transports formed elements, dissolved molecules, and ions
      • Carries oxygen to and carbon dioxide from the lungs
      • Transports nutrients, hormones, heat, and waste products (e.g., carbon dioxide, urea)
    • Regulates body conditions
      • Body temperature: Absorbs heat; releases heat at skin blood vessels.
      • Body pH: Absorbs acids and bases; contains chemical buffers (e.g., bicarbonate).
      • Fluid balance: Adds water from the GI tract; loses water in urine, skin, and respiration; exchanges fluid with interstitial fluid, maintains osmotic balance with proteins and ions.
    • Protects against pathogens: Leukocytes, plasma proteins, and other immune system molecules.
    • Protects against blood loss: Platelets and plasma proteins.

    Blood Plasma

    • Accounts for ~55% of blood volume.
    • Liquid component transporting various substances.
    • Composition:
      • Mostly water (~90-92%)
      • Dissolved substances (8-10%): Electrolytes (Na+, K+, Ca2+, Cl-, HCO3-), nutrients, waste products (urea, creatinine, uric acid), hormones, and gases (O2, CO2, N2).

    Important Blood Proteins

    • Albumins: Smallest and most abundant (58%), exert significant colloid osmotic pressure, and transport lipids, hormones, and ions.
    • Fibrinogen: Key protein in blood clotting.

    Red Blood Cells (Erythrocytes)

    • Small, flexible, biconcave discs.
    • Lack nucleus and organelles, packed with hemoglobin.
    • Transport oxygen and carbon dioxide.
    • Why lack a nucleus?
      • More hemoglobin capacity.
      • Flexible shape for capillary passage.
      • Efficient gas exchange.
      • Increased lifespan (120 days) because they don't need to use oxygen internally.
    • Hemoglobin:
      • Red-pigmented protein.
      • Transports oxygen and carbon dioxide (oxygenated/deoxygenated forms).
      • Composed of four globins (two alpha, two beta chains), each with a heme group containing iron.
      • Oxygen binds to iron.

    White Blood Cells (Leukocytes)

    • Part of the immune system, defending against infections and abnormal cells.
    • Have a nucleus, different types with specific functions:
      • Neutrophils: Fight bacterial/fungal infections.
      • Lymphocytes: Include B cells (antibodies), and T cells (attack infected/cancerous cells).
      • Monocytes: Become macrophages engulfing pathogens and dead cells.
      • Eosinophils: Fight parasites and have a role in allergic reactions.
      • Basophils: Release histamine in allergic responses.

    Blood Types and Compatibility

    • Determined by antigens (A, B, Rh) on red blood cells.
    • Types: A, B, AB, O.
    • Rh factor (+/-)
    • Incompatible transfusion causes hemolysis (RBC destruction), agglutination (clumping), leading to serious reactions in the recipient.
    • Careful cross-matching is essential before transfusions.

    Hemostasis (Blood Clotting)

    • Three phases:
      • Vascular spasm: Blood vessel constriction, limiting leakage.
      • Platelet plug formation: Platelets adhere to exposed collagen fibers, forming a plug.
      • Coagulation: Blood transforms from liquid to gel, forming a fibrin mesh.

    Clot Breakdown (Fibrinolysis)

    • Dissolves clots via plasmin.
    • Plasminogen (inactive enzyme) converted to plasmin by activators.
    • Fibrin broken down into fragments.
    • Removal of fragments by macrophages.

    Undesirable Clotting (Thrombosis)

    • Thrombus: Stationary clot in a blood vessel.
    • Embolus: Clot that travels and blocks vessels.
    • Conditions: Deep vein thrombosis (DVT), pulmonary embolism (PE), stroke, heart attack.
    • Causes include blood stasis, hypercoagulability, endothelial injury.
    • Prevention and treatment: Medications (blood thinners), lifestyle changes, compression therapy.

    Digestive System

    • Organs (GI tract, accessory organs):
      • Mouth, teeth, saliva, esophagus, stomach, small intestine, liver, gallbladder, pancreas, large intestine.
    • Processes:
      • Ingestion: Food intake.
      • Propulsion: Moving food through GI tract.
      • Mechanical digestion: Breaking food into smaller pieces.
      • Chemical digestion: Breaking down food molecules with enzymes.
      • Absorption: Transport of nutrients into blood or lymph.
      • Excretion: Removal of undigested material.
    • Details for sections above can be found in details given. Function of Bile

    Bile is a digestive fluid produced by the liver and stored in the gallbladder. It plays a crucial role in fat digestion and absorption in the small intestine.

    Functions of Bile: 1. Emulsification of Fats • Bile contains bile salts that break large fat globules into smaller droplets, increasing the surface area for the enzyme pancreatic lipase to act on. • This process helps digest and absorb dietary fats efficiently. 2. Aids in Fat Absorption • The breakdown of fats by bile and pancreatic lipase produces monoglycerides and free fatty acids, which form micelles (tiny fat droplets surrounded by bile salts). • Micelles help transport fats to the intestinal lining for absorption. 3. Elimination of Waste Products • Bile contains bilirubin, a byproduct of red blood cell breakdown, which gives feces its brown color. • It also helps remove cholesterol and toxins from the body. 4. Alkalinization of Intestinal Contents • Bile is slightly alkaline, helping neutralize stomach acid in the small intestine, creating a suitable pH for pancreatic enzymes to work. 5. Facilitates Vitamin Absorption • Bile aids in the absorption of fat-soluble vitamins (A, D, E, K) by helping dissolve them in micelles for transport across the intestinal lining.

    Where is Bile Released? • When fatty food enters the duodenum (first part of the small intestine), the hormone cholecystokinin (CCK) signals the gallbladder to release bile into the bile duct, which then empties into the small intestine.

    Would you like more details on bile disorders like gallstones or liver disease?

    Hepatic Blood Flow

    The liver receives blood from two main sources: 1. Hepatic Artery – Supplies oxygenated blood from the heart (~25% of liver’s blood supply). 2. Hepatic Portal Vein – Supplies nutrient-rich, deoxygenated blood from the digestive organs (~75% of liver’s blood supply).

    After processing, blood exits the liver through the hepatic veins into the inferior vena cava, which returns blood to the heart.

    Pathway of Hepatic Blood Flow: 1. Hepatic Artery (Oxygenated Blood) • Branches from the celiac trunk (off the aorta). • Delivers oxygen-rich blood to hepatocytes (liver cells). 2. Hepatic Portal Vein (Nutrient-Rich Blood) • Formed by the union of the superior mesenteric vein (from the small intestine) and the splenic vein. • Carries nutrients, toxins, and hormones from the digestive tract for processing in the liver. 3. Liver Sinusoids • Capillary-like structures in the liver where hepatic artery and portal vein blood mix. • Kupffer cells (liver macrophages) remove bacteria and toxins. • Hepatocytes process nutrients, detoxify chemicals, and produce bile. 4. Central Veins → Hepatic Veins → Inferior Vena Cava • Processed blood drains into central veins, which merge into hepatic veins. • Hepatic veins empty into the inferior vena cava, returning blood to the heart.

    Functions of Hepatic Blood Flow • Nutrient Processing: Regulates glucose, amino acids, and lipids. • Detoxification: Removes drugs, alcohol, and toxins. • Immune Function: Kupffer cells filter pathogens. • Bile Production: Helps digest fats and remove waste.

    Would you like a diagram or details on liver diseases affecting blood flow (e.g., cirrhosis, portal hypertension)?

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    Description

    Explore the vital roles of blood in transporting elements, regulating body conditions, and protecting against pathogens. This quiz also delves into the composition of blood plasma, which constitutes a significant portion of blood volume and its various dissolved substances.

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