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Questions and Answers
What is the primary function of pH buffering in the body?
What is the primary function of pH buffering in the body?
Erythrocytes are nucleated cells.
Erythrocytes are nucleated cells.
False (B)
What is the primary function of red blood cells (erythrocytes)?
What is the primary function of red blood cells (erythrocytes)?
What is the primary component of plasma that contributes to osmotic pressure?
What is the primary component of plasma that contributes to osmotic pressure?
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The shape of erythrocytes is a ______ disc.
The shape of erythrocytes is a ______ disc.
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Plasma is the liquid component of blood, making up approximately 55% of its volume.
Plasma is the liquid component of blood, making up approximately 55% of its volume.
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What are the three main formed elements found in blood?
What are the three main formed elements found in blood?
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Which of the following are NOT considered formed elements of blood?
Which of the following are NOT considered formed elements of blood?
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Match the following components of blood with their primary function:
Match the following components of blood with their primary function:
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The percentage of red blood cells in the blood is referred to as the ______.
The percentage of red blood cells in the blood is referred to as the ______.
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Match the plasma protein with its primary function:
Match the plasma protein with its primary function:
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Which of the following is NOT a physical characteristic of blood?
Which of the following is NOT a physical characteristic of blood?
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What is the approximate temperature of blood in degrees Celsius?
What is the approximate temperature of blood in degrees Celsius?
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Blood is heavier than water and has a higher viscosity due to the presence of plasma proteins and formed elements.
Blood is heavier than water and has a higher viscosity due to the presence of plasma proteins and formed elements.
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The hormone ______ accelerates the production of platelets.
The hormone ______ accelerates the production of platelets.
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What is the main procedure used to examine red marrow when leukemia is suspected?
What is the main procedure used to examine red marrow when leukemia is suspected?
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Platelets are attracted to an intact endothelium and become 'sticky' when a vessel is broken.
Platelets are attracted to an intact endothelium and become 'sticky' when a vessel is broken.
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What are the three main steps involved in hemostasis?
What are the three main steps involved in hemostasis?
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Match the following terms with their definitions:
Match the following terms with their definitions:
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Which type of white blood cell is the largest and changes into macrophages?
Which type of white blood cell is the largest and changes into macrophages?
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Eosinophils are primarily involved in fighting chronic infections like tuberculosis.
Eosinophils are primarily involved in fighting chronic infections like tuberculosis.
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What do B lymphocytes produce?
What do B lymphocytes produce?
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The order of relative abundance of WBCs in the blood starts with neutrophils, followed by lymphocytes, monocytes, and then __________.
The order of relative abundance of WBCs in the blood starts with neutrophils, followed by lymphocytes, monocytes, and then __________.
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Match the following white blood cells with their primary function:
Match the following white blood cells with their primary function:
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What happens when Blood Group A receives Anti-A antibodies?
What happens when Blood Group A receives Anti-A antibodies?
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Blood Group O has no antigens on red blood cells.
Blood Group O has no antigens on red blood cells.
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What antibodies are present in the plasma of Blood Group O?
What antibodies are present in the plasma of Blood Group O?
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A Rh- individual will produce ______ antibodies if they receive Rh+ blood for the second time.
A Rh- individual will produce ______ antibodies if they receive Rh+ blood for the second time.
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Match the Blood Group to its corresponding antibody presence:
Match the Blood Group to its corresponding antibody presence:
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What is the primary function of hemoglobin in red blood cells?
What is the primary function of hemoglobin in red blood cells?
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Sickle-cell anemia is caused by a change in one of the amino acids in hemoglobin.
Sickle-cell anemia is caused by a change in one of the amino acids in hemoglobin.
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What is the normal range of hemoglobin content for male adults in grams per deciliter?
What is the normal range of hemoglobin content for male adults in grams per deciliter?
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An excessive increase in the number of erythrocytes is called __________.
An excessive increase in the number of erythrocytes is called __________.
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Match the types of leukocytes with their characteristics:
Match the types of leukocytes with their characteristics:
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What can cause polycythemia?
What can cause polycythemia?
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Mature red blood cells do not contain any nuclei.
Mature red blood cells do not contain any nuclei.
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What happens to the oxygen content in the blood when red blood cells are sickled?
What happens to the oxygen content in the blood when red blood cells are sickled?
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Flashcards
Permeability
Permeability
The ability of a membrane to allow substances to pass through it.
HCO3-
HCO3-
Bicarbonate, a key component in pH buffering in the blood.
pH Buffering
pH Buffering
A process that resists changes in pH levels of a solution.
Osmotic Balance
Osmotic Balance
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Albumin
Albumin
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Erythrocytes
Erythrocytes
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Biconcave Discs
Biconcave Discs
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Anucleate
Anucleate
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Composition of Blood
Composition of Blood
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Plasma Volume in Blood
Plasma Volume in Blood
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Formed Elements
Formed Elements
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Erythrocytes Function
Erythrocytes Function
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Leukocytes Role
Leukocytes Role
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Platelets Purpose
Platelets Purpose
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Blood Characteristics
Blood Characteristics
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Main Components of Plasma
Main Components of Plasma
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Histamine
Histamine
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Agranulocytes
Agranulocytes
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Monocytes
Monocytes
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Lymphocytes
Lymphocytes
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Relative abundance of WBCs
Relative abundance of WBCs
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Thrombopoietin
Thrombopoietin
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Bone Marrow Biopsy
Bone Marrow Biopsy
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Hemostasis
Hemostasis
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Vascular Spasm
Vascular Spasm
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Platelet Plug Formation
Platelet Plug Formation
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Blood Group O
Blood Group O
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Agglutination Reaction
Agglutination Reaction
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Rh Blood Group System
Rh Blood Group System
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Rh- Transfusion Reaction
Rh- Transfusion Reaction
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Sensitization in Rh Reaction
Sensitization in Rh Reaction
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Hemoglobin
Hemoglobin
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Normal Hb Levels
Normal Hb Levels
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Sickle-cell anemia
Sickle-cell anemia
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Polycythemia
Polycythemia
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Leukocytes
Leukocytes
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Neutrophils
Neutrophils
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Granulocytes vs Agranulocytes
Granulocytes vs Agranulocytes
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Study Notes
Blood Composition and Volume
- Blood is a fluid connective tissue, thick and homogeneous
- It comprises 55% plasma and 45% formed elements
- Plasma, the liquid portion, is about 90% water
- Plasma proteins, including albumin, fibrinogen, and globulins, contribute to osmotic balance, blood clotting, and defense
- Dissolved substances transported by blood include nutrients, waste products, respiratory gases, hormones, electrolytes, and salts
Formed Elements
- Formed elements (45%) are cells and cell fragments
- Erythrocytes (red blood cells): 4-6 million per mm³; transport oxygen and carbon dioxide
- Leukocytes (white blood cells): 4,800-10,800 per mm³; essential for defense and immunity
- Platelets (thrombocytes): 250,000-400,000 per mm³; crucial for blood clotting
Physical Characteristics of Blood
- Sticky and opaque (not clear) with a metallic taste
- Color: scarlet (oxygen-rich) to dull red (carbon dioxide-rich)
- Heavier than water, about five times thicker
- Slightly alkaline; pH (7.35–7.45)
- Temperature: slightly higher than body temperature (38°C)
- Approximately 8% of body weight
- Volume: 5–6 liters in healthy adults
Hematopoiesis
- Hematopoiesis: the process of blood cell formation
- Occurs in red bone marrow or myeloid tissue
- In adults, found in axial skeleton, pectoral and pelvic girdles, and proximal epiphyses of the humerus and femur
- Stimulated by hormones (colony-stimulating factors and interleukins)
- All formed elements originate from a stem cell, the hemocytoblast, in bone marrow
Erythrocytes (RBCs)
- Anucleate; unable to synthesize proteins, grow, or divide
- Mature RBCs are sacs of hemoglobin molecules
- As they age they become rigid and fragment in 100-120 days
- Eliminated by phagocytes in spleen, liver, and other tissues
- Reticulocytes are immature RBCs with some ER
- Production regulated by erythropoietin, a hormone primarily produced by the kidneys
- Normal values: 12-18 g/100ml of blood in males and 12-16 g/100ml of blood in women
Hemoglobin
- Hemoglobin is a protein in red blood cells that carries oxygen
- It contains iron, and its major function is transporting oxygen and a small amount of carbon dioxide
- Each RBC contains millions of hemoglobin molecules
Sickle Cell Anemia (SCA)
- Genetic disorder
- Caused by a change in a single amino acid within hemoglobin
- Resulting in abnormal hemoglobin
- Abnormal hemoglobin in RBCs causes them to become spiky and sharp
Polycythemia
- Excessive increase in the number of erythrocytes
- Can result from bone marrow cancer or a physiological response to high altitude
Leukocytes (WBCs)
- Contain a nucleus and usual organelles
- Function in defending the body against bacteria, viruses, parasites, and tumor cells
- Divided into granulocytes (neutrophils, eosinophils, basophils) and agranulocytes (lymphocytes, monocytes)
Platelets
- Fragments of megakaryocytes
- Crucial for the clotting process
- Normal count is approximately 150,000–400,000 per mm³
Hemostasis
- Process of stopping bleeding
- Involves three main mechanisms: vascular spasm, platelet plug formation, and coagulation (blood clotting)
Blood Typing & Transfusion
- ABO blood groups (A, B, AB, O) and Rh factor (positive or negative) are crucial for compatibility in transfusions
- Blood typing, using antibodies, identifies blood antigens
- Cross-matching tests compatibility between donor and recipient blood for safe transfusions
- Rh incompatibility can cause hemolytic disease of the newborn. -RhoGAM is an immune serum to prevent sensitization in Rh− mothers carrying Rh+ babies
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Description
Test your knowledge on the functions and components of blood in the human body. This quiz covers topics like the primary functions of erythrocytes, plasma, and blood characteristics. Challenge yourself with matching exercises and fill-in-the-blank questions.