Blood Disorders Overview for Dental Hygienists
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Questions and Answers

What role does Vitamin B12 play in the body?

  • Regulates blood pressure
  • Absorbs iron from food
  • Synthesizes hemoglobin
  • Synthesizes DNA and RNA (correct)
  • Which of the following is NOT a cause of iron deficiency anemia?

  • Lack of vitamin C (correct)
  • Dietary deficiency
  • Chronic blood loss
  • Malabsorption
  • Which symptom is specifically associated with iron deficiency anemia?

  • Recurrent aphthous ulcers
  • Angular cheilitis
  • Red beefy tongue
  • Brittle nails & koilonychia (correct)
  • What is one of the principal causes of folate deficiency?

    <p>Dietary deficiency</p> Signup and view all the answers

    How can Vitamin B12 deficiency be managed?

    <p>Regular intra-muscular injections of hydroxocobalamin</p> Signup and view all the answers

    Which of the following conditions can lead to anemia of chronic disease?

    <p>Chronic inflammatory diseases</p> Signup and view all the answers

    Which feature is characteristic of vitamin B12 deficiency?

    <p>Larger red blood cells</p> Signup and view all the answers

    What is the main risk associated with folate deficiency during pregnancy?

    <p>Neural tube defects in the fetus</p> Signup and view all the answers

    What is a notable dental aspect of deficiency anaemias?

    <p>Glossitis</p> Signup and view all the answers

    What is a potential management strategy for patients with anemia?

    <p>Regular maintenance dental care</p> Signup and view all the answers

    Which of the following correctly classifies blood disorders?

    <p>Anaemias, leukaemias, and other dyscrasias</p> Signup and view all the answers

    What is a characteristic feature of deficiency anaemias?

    <p>Lack of essential nutrients</p> Signup and view all the answers

    Which condition is specifically associated with sickle cell disease?

    <p>Production of abnormal hemoglobin</p> Signup and view all the answers

    What is one primary distinction between leukaemia and lymphoma?

    <p>Lymphoma mainly involves lymphatic tissues</p> Signup and view all the answers

    Which type of blood disorder results from abnormal proliferation of blood cells?

    <p>Leukaemia</p> Signup and view all the answers

    How do thalassemia and sickle cell disease primarily differ?

    <p>Sickle cell disease results from hemoglobin S mutation, while thalassemia is due to globin chain abnormalities</p> Signup and view all the answers

    Which type of leukaemia is most commonly seen in adults?

    <p>Chronic lymphocytic leukaemia</p> Signup and view all the answers

    Which of the following best explains the relevance of blood disorders to oral health management?

    <p>Oral health can be influenced by systemic conditions such as blood disorders</p> Signup and view all the answers

    What is a common implication for dental hygienists when treating patients with blood disorders?

    <p>Increased risk of bleeding during procedures</p> Signup and view all the answers

    What is the main cause of Aplastic Anaemia?

    <p>Depressed bone marrow function</p> Signup and view all the answers

    Which of the following conditions is NOT commonly associated with Anaemia of Chronic Disease?

    <p>Hypertension</p> Signup and view all the answers

    What is the typical outcome of Acute Lymphoblastic Leukaemia in children after treatment?

    <p>85% survival rate</p> Signup and view all the answers

    Which type of leukaemia is characterized by the aggressive proliferation of myeloid cells?

    <p>Acute Myeloid Leukaemia</p> Signup and view all the answers

    Which treatment is commonly used for Chronic Myeloid Leukaemia?

    <p>Tyrosine kinase inhibitors</p> Signup and view all the answers

    What type of lymphocytes grow uncontrollably in Lymphoma?

    <p>Lymphocytes in general</p> Signup and view all the answers

    Which statement accurately describes the symptoms of Leukaemia?

    <p>Common symptoms include lymphadenopathy and fatigue</p> Signup and view all the answers

    What is a common complication associated with Multiple Myeloma?

    <p>Formation of osteolytic lesions</p> Signup and view all the answers

    Which of the following treatments is typically avoided during the active phase of Leukaemia?

    <p>Dental treatment</p> Signup and view all the answers

    What is a key feature of Chronic Lymphocytic Leukaemia?

    <p>Too many immature lymphocytes</p> Signup and view all the answers

    What distinguishes lymphoma from leukaemia?

    <p>Lymphoma forms tumors in lymphatic tissues.</p> Signup and view all the answers

    What are common symptoms shared by leukaemia, lymphoma, and multiple myeloma?

    <p>Bone pain and infections</p> Signup and view all the answers

    In which condition does the body produce an excess of plasma cells?

    <p>Multiple myeloma</p> Signup and view all the answers

    What potential risk should dental professionals consider when treating patients on long-term bisphosphonates?

    <p>Osteoradionecrosis</p> Signup and view all the answers

    How does leukaemia differ from multiple myeloma in terms of cancer cell location?

    <p>Leukaemia originates in the bone marrow but spreads to the blood.</p> Signup and view all the answers

    Which statement should be considered regarding dental treatment for patients with blood cancers?

    <p>Dental treatments should be deferred if infections are present.</p> Signup and view all the answers

    What is a major complication of sickle cell disease related to red blood cell shape?

    <p>Clogging of blood vessels</p> Signup and view all the answers

    Which of the following is true about thalassaemia?

    <p>It often leads to early hemolysis due to fragile red blood cells.</p> Signup and view all the answers

    What is recommended for dental treatment in patients with Sickle Cell Trait?

    <p>Avoiding general anesthesia is advised.</p> Signup and view all the answers

    Which symptoms are characteristic of homozygous β-thalassaemia?

    <p>Severe skeletal deformities and chronic anaemia</p> Signup and view all the answers

    Which of the following is a health issue associated with sickle cell crisis?

    <p>Clogging of blood flow due to misshapen cells</p> Signup and view all the answers

    What is a common oral manifestation of thalassaemia?

    <p>Xerostomia can result from iron deposits</p> Signup and view all the answers

    In which of the following conditions is avoiding stress crucial?

    <p>Sickle Cell Disease</p> Signup and view all the answers

    Which statement about sickle cell trait is true?

    <p>Carriers are healthy but can pass the gene to offspring.</p> Signup and view all the answers

    What triggers a sickle cell crisis?

    <p>Physical exertion and dehydration</p> Signup and view all the answers

    What is the best method for preventing dental complications in patients with Sickle Cell Disease?

    <p>Preventive care and antibiotic prophylaxis for invasive treatments</p> Signup and view all the answers

    Study Notes

    Blood Disorders Overview

    • Blood disorders are a broad category encompassing various conditions affecting blood cells and components
    • This presentation covers different types of anemias, leukaemias, and other blood dyscrasias relevant to dental hygienists/therapists' roles
    • It emphasizes the importance of identifying patient needs, understanding disease effects, and tailoring treatment plans accordingly.

    Types of Blood Disorders

    • Anemias: Deficiency anemias (iron, B12, folate), haemolytic anemias (sickle cell disease, thalassemia), aplastic anemia, and anemia of chronic disease
    • Leukaemias: The various acute and chronic forms (lymphocytic, myeloid)
    • Other dyscrasias: multiple myeloma and lymphoma, conditions affecting the blood-forming cells.
    • Bleeding disorders: Thrombocytopenia/coagulopathies (a separate lecture topic)

    Anemia Specifics

    • Deficiency Anemias: Characterized by a lack of essential nutrients (iron, B12, folate) leading to smaller, paler red blood cells with reduced oxygen-carrying capacity. Causes include dietary deficiency, chronic blood loss, malabsorption, and pregnancy.
    • Haemolytic Anemias: Result from premature destruction of red blood cells. Inherited forms include sickle cell disease and thalassemia, while acquired forms stem from infections, medications, autoimmune disorders, or conditions like an enlarged spleen or mechanical heart valves.
    • Aplastic Anemia: Bone marrow depression leading to lower blood cell production.
    • Anaemia of Chronic Disease: A condition arising from ongoing immune responses related to chronic infections or underlying diseases (e.g., rheumatoid arthritis, kidney disease).

    Leukaemia Specifics

    • Leukaemias: Cancer involving white blood cell precursors, leading to the overproduction of immature blood cells. Classified as acute or chronic, lymphocytic or myeloid, depending on the type of blood cell involved and the speed of disease progression.
    • Acute Lymphocytic Leukemia: Common in children and young adults.
    • Acute Myeloid Leukemia: Most common acute form in adults.
    • Chronic Myeloid Leukemia: Primarily affects older adults, characterized by slow progression.
    • Chronic Lymphocytic Leukemia: Typically discovered late, often diagnosed in middle-aged or older individuals
    • Clinical features of all the mentioned leukaemias include: anaemia, symptoms like fatigue, paleness, frequent infections, and possible enlargement of lymph nodes

    Multiple Myeloma & Lymphoma

    • Multiple Myeloma: A cancer affecting antibody-producing plasma cells, often leading to bone lesions and complications due to faulty antibodies.
    • Lymphoma: Cancer arising from lymphocytes within the lymphatic system (like lymph nodes, spleen, or other lymphatic tissues)

    Management Considerations

    • General Management Principles: Prompt medical consultation (refer to a GP), iron supplements and preventive dental care regimes are crucial considerations. Patients should be monitored for complications and risks like infection.
    • Specific management for different conditions: Specific recommendations vary with individual conditions and the patient's needs, e.g avoiding general anesthetic in particular cases like sickle cell.

    Summary - Clinical Features

    • Dental implications for each type of blood disorder; the symptoms vary according to the specific blood disorder (including oral manifestations) affecting patients may vary.

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    Description

    This quiz provides an overview of blood disorders, including various types of anemias, leukaemias, and dyscrasias relevant to dental hygienists and therapists. Understanding these conditions is crucial for identifying patient needs and adapting treatment plans accordingly.

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