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Questions and Answers
Which of the following conditions would not lead to a decreased erythrocyte count?
Which of the following conditions would not lead to a decreased erythrocyte count?
What is the most common cause of microcytic anemia?
What is the most common cause of microcytic anemia?
What is the defining characteristic of macrocytic anemia?
What is the defining characteristic of macrocytic anemia?
Which of the following is a physiological cause of polycythemia?
Which of the following is a physiological cause of polycythemia?
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What is the typical cause of aplastic anemia?
What is the typical cause of aplastic anemia?
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What is the main function of the segmented neutrophil?
What is the main function of the segmented neutrophil?
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What is the reticulocyte count used for?
What is the reticulocyte count used for?
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Which of the following is NOT a component of a complete blood count (CBC)?
Which of the following is NOT a component of a complete blood count (CBC)?
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What is the difference between Hodgkin’s lymphoma and non-Hodgkin’s lymphoma?
What is the difference between Hodgkin’s lymphoma and non-Hodgkin’s lymphoma?
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What is the mean corpuscular volume (MCV)?
What is the mean corpuscular volume (MCV)?
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If a patient has iron deficiency anemia, what would you expect about their MCV and RDW?
If a patient has iron deficiency anemia, what would you expect about their MCV and RDW?
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Which of the following is NOT a potential cause of leukocytosis?
Which of the following is NOT a potential cause of leukocytosis?
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What is the average concentration of hemoglobin in a red blood cell relative to its volume called?
What is the average concentration of hemoglobin in a red blood cell relative to its volume called?
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Which of the following is NOT a potential cause of leukopenia?
Which of the following is NOT a potential cause of leukopenia?
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What type of anemia is characterized by a decreased MCV and increased RDW?
What type of anemia is characterized by a decreased MCV and increased RDW?
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A reticulocyte count of 0.2% in a patient with anemia suggests which of the following?
A reticulocyte count of 0.2% in a patient with anemia suggests which of the following?
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What is the primary difference between a low hematocrit (Hct) due to dehydration and a low Hct due to anemia?
What is the primary difference between a low hematocrit (Hct) due to dehydration and a low Hct due to anemia?
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Which of the following conditions is MOST LIKELY to present with an increased Mean Platelet Volume (MPV)?
Which of the following conditions is MOST LIKELY to present with an increased Mean Platelet Volume (MPV)?
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A patient presents with a low platelet count (thrombocytopenia). Which of the following is NOT a possible cause?
A patient presents with a low platelet count (thrombocytopenia). Which of the following is NOT a possible cause?
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Which red blood cell (RBC) index measures the average volume of a single RBC?
Which red blood cell (RBC) index measures the average volume of a single RBC?
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What is the significance of a high reticulocyte count in a patient with anemia?
What is the significance of a high reticulocyte count in a patient with anemia?
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Which of the following conditions is most likely to cause a low hematocrit (Hct)?
Which of the following conditions is most likely to cause a low hematocrit (Hct)?
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Which of the following is NOT a characteristic of a reticulocyte?
Which of the following is NOT a characteristic of a reticulocyte?
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Which of the following is NOT a characteristic of Reed-Sternberg cells, found in Hodgkin's lymphoma?
Which of the following is NOT a characteristic of Reed-Sternberg cells, found in Hodgkin's lymphoma?
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Which of the following conditions is NOT associated with an increase in serum ferritin levels?
Which of the following conditions is NOT associated with an increase in serum ferritin levels?
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A patient presents with a low transferrin saturation level. What is the most likely explanation for this?
A patient presents with a low transferrin saturation level. What is the most likely explanation for this?
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What is the primary function of transferrin in the body?
What is the primary function of transferrin in the body?
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Which of the following is the MOST accurate statement regarding the erythrocyte sedimentation rate (ESR)?
Which of the following is the MOST accurate statement regarding the erythrocyte sedimentation rate (ESR)?
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What is the main difference between ESR and C-reactive protein (CRP) in terms of their sensitivity to inflammation?
What is the main difference between ESR and C-reactive protein (CRP) in terms of their sensitivity to inflammation?
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Which of the following is NOT a common cause of an elevated C-reactive protein (CRP) level?
Which of the following is NOT a common cause of an elevated C-reactive protein (CRP) level?
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Which of the following tests is NOT typically included in a coagulation panel?
Which of the following tests is NOT typically included in a coagulation panel?
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Which of the following conditions would MOST likely result in an increase in bleeding time?
Which of the following conditions would MOST likely result in an increase in bleeding time?
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What is the primary goal of a coagulation panel?
What is the primary goal of a coagulation panel?
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What is a "left shift" in a white blood cell differential?
What is a "left shift" in a white blood cell differential?
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What type of cell is most likely to increase during a parasitic infection?
What type of cell is most likely to increase during a parasitic infection?
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Which of the following is a characteristic of chronic lymphocytic leukemia (CLL)?
Which of the following is a characteristic of chronic lymphocytic leukemia (CLL)?
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A blood smear is often ordered when a CBC detects abnormal values. What is the purpose of a blood smear?
A blood smear is often ordered when a CBC detects abnormal values. What is the purpose of a blood smear?
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What is the significance of Dohle bodies in a blood smear?
What is the significance of Dohle bodies in a blood smear?
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Which of the following is a hallmark feature of acute leukemia?
Which of the following is a hallmark feature of acute leukemia?
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What is the key difference between acute and chronic leukemia?
What is the key difference between acute and chronic leukemia?
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Which of the following statements about lymphomas is TRUE?
Which of the following statements about lymphomas is TRUE?
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What is the significance of a white blood cell differential?
What is the significance of a white blood cell differential?
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Flashcards
CBC Components
CBC Components
A series of tests providing information about RBCs, WBCs, and platelets.
RBC Indices
RBC Indices
Measurements of red blood cells, including MCV, MCH, and MCHC.
Anemia Causes
Anemia Causes
Conditions leading to decreased red blood cells or hemoglobin levels.
Ferritin vs Iron
Ferritin vs Iron
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White Blood Cell Types
White Blood Cell Types
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Erythrocyte count
Erythrocyte count
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Anemia
Anemia
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Macrocytic anemia
Macrocytic anemia
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Microcytic anemia
Microcytic anemia
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Pancytopenia
Pancytopenia
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MCV (Mean Corpuscular Volume)
MCV (Mean Corpuscular Volume)
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Megaloblastic Anemias
Megaloblastic Anemias
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RDW (Red Blood Cell Distribution Width)
RDW (Red Blood Cell Distribution Width)
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WBC Count
WBC Count
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Leukocytosis
Leukocytosis
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Reticulocytes
Reticulocytes
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Retic Count Reference Range
Retic Count Reference Range
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Increased Retic Count
Increased Retic Count
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Low Retic Count in Anemia
Low Retic Count in Anemia
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Hemoglobin (Hgb)
Hemoglobin (Hgb)
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Hematocrit (Hct)
Hematocrit (Hct)
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Platelet Count (Plt)
Platelet Count (Plt)
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Mean Corpuscular Volume (MCV)
Mean Corpuscular Volume (MCV)
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Left Shift
Left Shift
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Right Shift
Right Shift
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Neutrophilia without Bands
Neutrophilia without Bands
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Lymphocyte Percentage
Lymphocyte Percentage
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Hypersegmented Neutrophils
Hypersegmented Neutrophils
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Leukemia
Leukemia
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Auer Rods
Auer Rods
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Lymphomas
Lymphomas
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Hodgkin’s lymphoma (HL)
Hodgkin’s lymphoma (HL)
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Non-Hodgkin’s lymphoma (NHL)
Non-Hodgkin’s lymphoma (NHL)
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Iron Panel Components
Iron Panel Components
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Serum Iron
Serum Iron
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Total Iron Binding Capacity (TIBC)
Total Iron Binding Capacity (TIBC)
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Transferrin Saturation
Transferrin Saturation
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Ferritin
Ferritin
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Erythrocyte Sedimentation Rate (ESR)
Erythrocyte Sedimentation Rate (ESR)
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C-reactive Protein (CRP)
C-reactive Protein (CRP)
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Coagulation Panel Tests
Coagulation Panel Tests
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Study Notes
Hematology Week 3
- The course covers hematology, focusing on blood components and conditions.
- Instructional objectives include inventorying complete blood count (CBC) components, comparing anemia and polycythemia causes, debating reticulocyte count importance, contrasting iron-related elements and their indications, examining B12, folate and megaloblastic anemia relationship, inventorying blood cell functions and irregularities, contrasting lymphomas, and comparing different blood cancers.
Blood Components
- CBC: A series of blood tests providing information about red blood cells (RBCs), platelets, and white blood cells (WBCs). Easy, quick, and inexpensive.
- RBCs: Hemoglobin, hematocrit, RBC indices (MCV, MCH, MCHC, and RDW), and erythrocyte count.
- WBCs: White blood cell count and differential of neutrophils, lymphocytes, monocytes, eosinophils, and basophils.
- Platelets: Essential for blood clotting. Measured by platelet count.
Blood Cell Indices
- MCV: The average size of red blood cells.
- MCH: The average amount of hemoglobin in a red blood cell.
- MCHC: The average concentration of hemoglobin in a red blood cell.
- RDW: The variation in red blood cell sizes in a sample. Usually used in classifying anemias.
- MPV: The average size of platelets.
Anemias
- Macrocytic anemia: Megaloblastic anemia, DNA synthesis impairment during RBC production.
- Microcytic anemia: Insufficient iron intake, increased need, insufficient absorption, or increased blood loss, iron deficiency, etc. Characterized by small red blood cells.
- Causes of anemia: Decrease in RBC production by bone marrow, conditions that cause loss of red blood cells, and dilution of fluids in the body.
Other blood conditions
- Polycythemia: Increased RBC count. Physiologically induced due to increased oxygen requirements or chronic hypoxia. Dehydration can artificially increase RBCs.
- Leukemia: Cancer arising in the blood. Divided into acute and chronic types.
- Lymphomas: Cancers from lymphocytes. Two main categories: Non-Hodgkin's lymphoma (NHL) and Hodgkin's lymphoma (HL).
- Reticulocytes: Immature red blood cells, increased levels indicate high red blood cell production (e.g. trying to correct another condition) or blood loss.
- Hemoglobin (Hgb): RBC protein for oxygen transport. Lower hemoglobin represents possible anemia.
Blood Tests Associated with Hematologic Conditions
- Iron Panel: Serum iron, TIBC/transferrin, transferrin saturation, and ferritin. Measures iron levels, capacity, and storage.
- ESR (Erythrocyte Sedimentation Rate): Measures how quickly red blood cells settle. Elevated in inflammatory conditions.
- CRP (C-reactive protein): Acute-phase reactant indicating inflammation or infection. More sensitive than ESR.
- Coagulation Panel: Tests measure efficiency and speed of blood clotting. Includes bleeding time, protime/prothrombin time (PT), PT/INR, partial thromboplastin time (PTT), and fibrinogen.
- D-dimer: Indicates clot degradation, elevated suggests thrombosis.
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Description
Test your knowledge on key concepts in hematology, focusing on various types of anemia, blood counts, and related disorders. This quiz covers the definitions, causes, and characteristics that distinguish different blood conditions. Perfect for students in health sciences or anyone interested in understanding blood health.