Blood Component Transfusion Reaction Overview

Play an AI-generated podcast conversation about this lesson

Which type of patient is at highest risk for developing a transfusion reaction?

Lymphopenic patients (correct)

Patients with a history of allergies

Patients with a history of heart disease

Patients with chronic kidney disease

What is the most common sign or symptom of a transfusion-associated sepsis (TAS) reaction?

Nausea and vomiting

Chest pain

Fever and rigors (correct)

Shortness of breath

Which of the following is an example of an acute transfusion reaction?

Delayed serological transfusion reaction

Febrile non-hemolytic transfusion reaction

Transfusion-related acute lung injury (correct)

Post-transfusion purpura

What is the primary cause of a transfusion-associated circulatory overload (TACO) reaction?

Rapid transfusion of a large volume of blood Signup and view all the answers

What is the long-term complication of repeated red blood cell transfusions?

Iron overload Signup and view all the answers

Which type of transfusion reaction typically develops after 24 hours post-transfusion?

Delayed hemolytic transfusion reaction Signup and view all the answers

Which of the following is a clinical sign or symptom of a transfusion reaction?

Flushing or rash Signup and view all the answers

Which of the following is a sign or symptom of iron overload from repeated transfusions?

Muscle weakness and fatigue Signup and view all the answers

Which laboratory finding is associated with acute transfusion reactions?

Decreased platelet count Signup and view all the answers

What is the recommended first-line therapy for an acute transfusion reaction?

Corticosteroids Signup and view all the answers

What is the primary pathophysiology underlying transfusion reactions?

Immune system overreaction Signup and view all the answers

Which of the following is a recommended step in the clinical workup of a suspected transfusion reaction?

Obtain samples for serological testing Signup and view all the answers

What are the two types of Hemolytic Transfusion Reaction (HTR) categorized based on timing?

Immediate HTR and Delayed HTR Signup and view all the answers

What is the primary site where Hemolysis occurs in Intravascular HTR?

Within RBCs Signup and view all the answers

Which laboratory investigation is indicative of Urticarial (Allergic) Transfusion Reaction?

DCT positive Signup and view all the answers

What does the presence of pyrogens from WBCs lead to in the recipient during a Hemolytic Transfusion Reaction?

Elevated body temperature Signup and view all the answers

How can Intravascular HTR be masked if anti-pyretics are used before starting transfusion?

By decreasing fever Signup and view all the answers

What is a recommended therapy to prevent Hemolytic Transfusion Reactions?

Avoiding leukocyte-poor red cells Signup and view all the answers