Blood Component Transfusion Reaction Overview
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Questions and Answers

Which type of patient is at highest risk for developing a transfusion reaction?

  • Lymphopenic patients (correct)
  • Patients with a history of allergies
  • Patients with a history of heart disease
  • Patients with chronic kidney disease
  • What is the most common sign or symptom of a transfusion-associated sepsis (TAS) reaction?

  • Nausea and vomiting
  • Chest pain
  • Fever and rigors (correct)
  • Shortness of breath
  • Which of the following is an example of an acute transfusion reaction?

  • Delayed serological transfusion reaction
  • Febrile non-hemolytic transfusion reaction
  • Transfusion-related acute lung injury (correct)
  • Post-transfusion purpura
  • What is the primary cause of a transfusion-associated circulatory overload (TACO) reaction?

    <p>Rapid transfusion of a large volume of blood</p> Signup and view all the answers

    What is the long-term complication of repeated red blood cell transfusions?

    <p>Iron overload</p> Signup and view all the answers

    Which type of transfusion reaction typically develops after 24 hours post-transfusion?

    <p>Delayed hemolytic transfusion reaction</p> Signup and view all the answers

    Which of the following is a clinical sign or symptom of a transfusion reaction?

    <p>Flushing or rash</p> Signup and view all the answers

    Which of the following is a sign or symptom of iron overload from repeated transfusions?

    <p>Muscle weakness and fatigue</p> Signup and view all the answers

    Which laboratory finding is associated with acute transfusion reactions?

    <p>Decreased platelet count</p> Signup and view all the answers

    What is the recommended first-line therapy for an acute transfusion reaction?

    <p>Corticosteroids</p> Signup and view all the answers

    What is the primary pathophysiology underlying transfusion reactions?

    <p>Immune system overreaction</p> Signup and view all the answers

    Which of the following is a recommended step in the clinical workup of a suspected transfusion reaction?

    <p>Obtain samples for serological testing</p> Signup and view all the answers

    What are the two types of Hemolytic Transfusion Reaction (HTR) categorized based on timing?

    <p>Immediate HTR and Delayed HTR</p> Signup and view all the answers

    What is the primary site where Hemolysis occurs in Intravascular HTR?

    <p>Within RBCs</p> Signup and view all the answers

    Which laboratory investigation is indicative of Urticarial (Allergic) Transfusion Reaction?

    <p>DCT positive</p> Signup and view all the answers

    What does the presence of pyrogens from WBCs lead to in the recipient during a Hemolytic Transfusion Reaction?

    <p>Elevated body temperature</p> Signup and view all the answers

    How can Intravascular HTR be masked if anti-pyretics are used before starting transfusion?

    <p>By decreasing fever</p> Signup and view all the answers

    What is a recommended therapy to prevent Hemolytic Transfusion Reactions?

    <p>Avoiding leukocyte-poor red cells</p> Signup and view all the answers

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