Blood Component Transfusion Reaction Overview
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Questions and Answers

Which type of patient is at highest risk for developing a transfusion reaction?

  • Lymphopenic patients (correct)
  • Patients with a history of allergies
  • Patients with a history of heart disease
  • Patients with chronic kidney disease

What is the most common sign or symptom of a transfusion-associated sepsis (TAS) reaction?

  • Nausea and vomiting
  • Chest pain
  • Fever and rigors (correct)
  • Shortness of breath

Which of the following is an example of an acute transfusion reaction?

  • Delayed serological transfusion reaction
  • Febrile non-hemolytic transfusion reaction
  • Transfusion-related acute lung injury (correct)
  • Post-transfusion purpura

What is the primary cause of a transfusion-associated circulatory overload (TACO) reaction?

<p>Rapid transfusion of a large volume of blood (A)</p> Signup and view all the answers

What is the long-term complication of repeated red blood cell transfusions?

<p>Iron overload (C)</p> Signup and view all the answers

Which type of transfusion reaction typically develops after 24 hours post-transfusion?

<p>Delayed hemolytic transfusion reaction (A)</p> Signup and view all the answers

Which of the following is a clinical sign or symptom of a transfusion reaction?

<p>Flushing or rash (C)</p> Signup and view all the answers

Which of the following is a sign or symptom of iron overload from repeated transfusions?

<p>Muscle weakness and fatigue (B)</p> Signup and view all the answers

Which laboratory finding is associated with acute transfusion reactions?

<p>Decreased platelet count (C)</p> Signup and view all the answers

What is the recommended first-line therapy for an acute transfusion reaction?

<p>Corticosteroids (B)</p> Signup and view all the answers

What is the primary pathophysiology underlying transfusion reactions?

<p>Immune system overreaction (C)</p> Signup and view all the answers

Which of the following is a recommended step in the clinical workup of a suspected transfusion reaction?

<p>Obtain samples for serological testing (A)</p> Signup and view all the answers

What are the two types of Hemolytic Transfusion Reaction (HTR) categorized based on timing?

<p>Immediate HTR and Delayed HTR (C)</p> Signup and view all the answers

What is the primary site where Hemolysis occurs in Intravascular HTR?

<p>Within RBCs (D)</p> Signup and view all the answers

Which laboratory investigation is indicative of Urticarial (Allergic) Transfusion Reaction?

<p>DCT positive (A)</p> Signup and view all the answers

What does the presence of pyrogens from WBCs lead to in the recipient during a Hemolytic Transfusion Reaction?

<p>Elevated body temperature (B)</p> Signup and view all the answers

How can Intravascular HTR be masked if anti-pyretics are used before starting transfusion?

<p>By decreasing fever (B)</p> Signup and view all the answers

What is a recommended therapy to prevent Hemolytic Transfusion Reactions?

<p>Avoiding leukocyte-poor red cells (D)</p> Signup and view all the answers

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