29 Questions
What is a key factor to consider when selecting a medication for bipolar disorder?
Type of episode (I vs. II)
Which of the following is NOT mentioned as a consideration when choosing a medication for bipolar disorder?
Adherence rate to a particular brand
Approximately what percentage of bipolar disorder patients experience more than 4 episodes in their lifetime?
80%
Which of the following is considered a mood stabilizer in the treatment of bipolar disorder?
Lithium
What aspect is involved in the initial assessment for bipolar disorder treatment?
Completing family, social, and medical history
In relation to bipolar disorder, what does a '7-fold risk' mean?
7 times higher risk than average
What is a potential risk associated with the rapid discontinuation of lithium?
Early relapse of symptoms
What is a known side effect related to lithium interaction?
Unmasking of Brugada syndrome
In bipolar disorder, what is considered an early symptom that should be closely monitored?
Change of thinking
Why should patients be counseled numerous times before making any changes in their lithium regimen?
To avoid destabilization and early relapse of symptoms
What is a potential fetal risk associated with lithium use?
Development of Ebstein's anomaly in the fetus
Which condition can be unmasked by the use of lithium as per the text?
Brugada syndrome
What is the primary mechanism of action for carbamazepine that makes it an 'auto-inducer'?
Carbamazepine generates active metabolites that induce its own metabolism.
What is the typical timeline for the auto-induction process of carbamazepine?
Auto-induction begins after 3-5 days of therapy and is complete in 3-5 weeks.
Which of the following is a black box warning associated with carbamazepine?
Rash
What is the primary FDA-approved use of carbamazepine?
All of the above
Which of the following is a common adverse effect associated with carbamazepine therapy?
Hyponatremia
What type of genetic marker is associated with the risk of Stevens-Johnson syndrome/Toxic Epidermal Necrolysis (SJS/TEN) with carbamazepine?
HLA-B*1502
What is Valproic Acid (VPA) FDA approved for?
Acute mania
Which condition is NOT listed as having evidence of effectiveness with Valproic Acid (VPA)?
Chronic insomnia
What is a Black Box Warning associated with Valproic Acid (VPA)?
Teratogenicity
Which form of Valproic Acid is available in enteric-coated tablets?
Divalproex Sodium (Depakote)
What adverse effect is NOT associated with the use of Valproic Acid (VPA)?
Vision improvement
What is the clinical concern regarding Valproic Acid (VPA) interaction during the first trimester of gestation?
Teratogenicity
What is the purpose of the Young Mania Rating Scale (YMRS)?
Screening and assessing symptom severity of mania
How long does it typically take to administer the Young Mania Rating Scale (YMRS)?
30 minutes
What does a YMRS score of 19-24 indicate?
Moderate mania
How many items are included in the Young Mania Rating Scale (YMRS)?
11 items
What is the scoring range for the Young Mania Rating Scale (YMRS)?
0-25
Test your knowledge on the diagnostic and pharmacological aspects of bipolar disorder according to the DSM-5. Assessments including mental status exams, family history evaluation, and laboratory tests are covered in this quiz.
Make Your Own Quizzes and Flashcards
Convert your notes into interactive study material.
Get started for free
