Podcast
Questions and Answers
What is the immediate substrate for fatty acid biosynthesis?
What is the immediate substrate for fatty acid biosynthesis?
- Acetyl-CoA (correct)
- Citrate
- NADPH
- Pyruvate
Which of the following is NOT a cofactor required for fatty acid biosynthesis?
Which of the following is NOT a cofactor required for fatty acid biosynthesis?
- Mn2+
- FADH2 (correct)
- HCO3–
- ATP
Where is nearly all of the Acetyl CoA used in fatty acid synthesis formed?
Where is nearly all of the Acetyl CoA used in fatty acid synthesis formed?
- Cytosol
- Endoplasmic Reticulum
- Lysosomes
- Mitochondria (correct)
How is Acetyl CoA transported out of the mitochondria for fatty acid synthesis?
How is Acetyl CoA transported out of the mitochondria for fatty acid synthesis?
Which tissue contains an extra-mitochondrial system for synthesizing fatty acids?
Which tissue contains an extra-mitochondrial system for synthesizing fatty acids?
What substance is used to source CO2 in the biosynthesis of fatty acids?
What substance is used to source CO2 in the biosynthesis of fatty acids?
What is the role of citrate in fatty acid biosynthesis?
What is the role of citrate in fatty acid biosynthesis?
How does an increase in mitochondrial acetyl-CoA and ATP affect citrate's movement?
How does an increase in mitochondrial acetyl-CoA and ATP affect citrate's movement?
Which molecule inhibits the enzyme acetyl-CoA carboxylase in fatty acid biosynthesis?
Which molecule inhibits the enzyme acetyl-CoA carboxylase in fatty acid biosynthesis?
What triggers the transition of Acetyl-CoA Carboxylase from an active conformation to an inactive form?
What triggers the transition of Acetyl-CoA Carboxylase from an active conformation to an inactive form?
In fatty acid biosynthesis, what is the function of palmitoyl Co A?
In fatty acid biosynthesis, what is the function of palmitoyl Co A?
What is the consequence of citrate converting the enzyme into an active polymeric form?
What is the consequence of citrate converting the enzyme into an active polymeric form?
What is the fate of oxaloacetate in the process of citrate cleavage?
What is the fate of oxaloacetate in the process of citrate cleavage?
Which enzyme converts malate to pyruvate in the context of fatty acid synthesis?
Which enzyme converts malate to pyruvate in the context of fatty acid synthesis?
What is the chief source of hydrogen required for reductive synthesis of fatty acids?
What is the chief source of hydrogen required for reductive synthesis of fatty acids?
Where does pyruvate and malate pass through in the mitochondrial system?
Where does pyruvate and malate pass through in the mitochondrial system?
What is the function of NADPH in fatty acid synthesis?
What is the function of NADPH in fatty acid synthesis?