Biosynthesis of Fatty Acids and Triacylglycerol with Insulin-Dependent Glucose Utilization
17 Questions
0 Views

Choose a study mode

Play Quiz
Study Flashcards
Spaced Repetition
Chat to Lesson

Podcast

Play an AI-generated podcast conversation about this lesson

Questions and Answers

What is the immediate substrate for fatty acid biosynthesis?

  • Acetyl-CoA (correct)
  • Citrate
  • NADPH
  • Pyruvate

Which of the following is NOT a cofactor required for fatty acid biosynthesis?

  • Mn2+
  • FADH2 (correct)
  • HCO3–
  • ATP

Where is nearly all of the Acetyl CoA used in fatty acid synthesis formed?

  • Cytosol
  • Endoplasmic Reticulum
  • Lysosomes
  • Mitochondria (correct)

How is Acetyl CoA transported out of the mitochondria for fatty acid synthesis?

<p>As citrate (D)</p> Signup and view all the answers

Which tissue contains an extra-mitochondrial system for synthesizing fatty acids?

<p>Liver (B)</p> Signup and view all the answers

What substance is used to source CO2 in the biosynthesis of fatty acids?

<p>HCO3– (B)</p> Signup and view all the answers

What is the role of citrate in fatty acid biosynthesis?

<p>Facilitates the conversion of an inactive enzyme to an active form (D)</p> Signup and view all the answers

How does an increase in mitochondrial acetyl-CoA and ATP affect citrate's movement?

<p>Promotes the transport of citrate out of mitochondria (D)</p> Signup and view all the answers

Which molecule inhibits the enzyme acetyl-CoA carboxylase in fatty acid biosynthesis?

<p>Malonyl Co A (B)</p> Signup and view all the answers

What triggers the transition of Acetyl-CoA Carboxylase from an active conformation to an inactive form?

<p>Increased levels of Acetyl-CoA (D)</p> Signup and view all the answers

In fatty acid biosynthesis, what is the function of palmitoyl Co A?

<p>Halts the production of acetyl-CoA (A)</p> Signup and view all the answers

What is the consequence of citrate converting the enzyme into an active polymeric form?

<p>Synthesis of new fatty acids (A)</p> Signup and view all the answers

What is the fate of oxaloacetate in the process of citrate cleavage?

<p>Channeled towards glucose production (A)</p> Signup and view all the answers

Which enzyme converts malate to pyruvate in the context of fatty acid synthesis?

<p>Malic enzyme (B)</p> Signup and view all the answers

What is the chief source of hydrogen required for reductive synthesis of fatty acids?

<p>Oxidative reactions in the pentose phosphate pathway (C)</p> Signup and view all the answers

Where does pyruvate and malate pass through in the mitochondrial system?

<p>Inner mitochondrial membrane (D)</p> Signup and view all the answers

What is the function of NADPH in fatty acid synthesis?

<p>Donor of reducing equivalents (D)</p> Signup and view all the answers

More Like This

Lipids 1
53 questions

Lipids 1

VerifiableSlideWhistle avatar
VerifiableSlideWhistle
Use Quizgecko on...
Browser
Browser