Biomarkers in Alzheimer's Disease
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Questions and Answers

Which of the following is a key feature of Alzheimer's disease biomarkers?

  • They primarily rely on the presence of symptoms for diagnosis
  • They are only detectable in the later stages of the disease
  • They have low sensitivity and specificity in distinguishing AD from dementia
  • They can be used to diagnose Alzheimer's disease in the early stage (correct)
  • What is the role of amyloid beta (Aβ) in Alzheimer's disease diagnosis?

  • It is a good indicator of AD disease (correct)
  • It is primarily used to diagnose other types of dementia
  • It has low sensitivity and specificity in distinguishing AD from dementia
  • It is only detectable in the cerebrospinal fluid (CSF)
  • Why is it imperative to diagnose Alzheimer's disease as soon as possible?

  • The biomarkers are only effective in the later stages of the disease
  • There are no effective treatments available for AD
  • Symptoms of AD are easily recognizable in the early stage
  • Neuropathologic changes of AD precede the symptoms by years (correct)
  • What is the sensitivity and specificity of amyloid beta biomarker in distinguishing AD from dementia?

    <p>80% or above</p> Signup and view all the answers

    What makes amyloid beta peptides a promising candidate for biological markers in Alzheimer's disease?

    <p>They are solubilized and detected in CSF and blood plasma</p> Signup and view all the answers

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