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Questions and Answers
Which of the following is an example of a liquid tissue?
Which of the following is an example of a liquid tissue?
Which type of junction creates a seal that prevents substances from passing between cells?
Which type of junction creates a seal that prevents substances from passing between cells?
Which transmembrane glycoproteins are found in adherens junctions?
Which transmembrane glycoproteins are found in adherens junctions?
Which basic tissue type generates body heat and movement?
Which basic tissue type generates body heat and movement?
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Which feature is characteristic of non-ciliated simple columnar epithelium?
Which feature is characteristic of non-ciliated simple columnar epithelium?
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Which protein primarily composes the plaques in desmosomes?
Which protein primarily composes the plaques in desmosomes?
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Where is pseudostratified columnar epithelium most commonly found?
Where is pseudostratified columnar epithelium most commonly found?
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What is the key function of intermediate filaments?
What is the key function of intermediate filaments?
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What is the primary function of stratified squamous epithelium?
What is the primary function of stratified squamous epithelium?
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Which of the following scientists specialize in laboratory studies of cells and tissues for diagnoses?
Which of the following scientists specialize in laboratory studies of cells and tissues for diagnoses?
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Which epithelial tissue type allows urinary organs to stretch and maintain a protective lining?
Which epithelial tissue type allows urinary organs to stretch and maintain a protective lining?
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Which cytoskeletal components are responsible for generating movement and providing mechanical support?
Which cytoskeletal components are responsible for generating movement and providing mechanical support?
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What distinguishes stratified cuboidal epithelium from other epithelial tissues?
What distinguishes stratified cuboidal epithelium from other epithelial tissues?
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What is the function of goblet cells in non-ciliated simple columnar epithelium?
What is the function of goblet cells in non-ciliated simple columnar epithelium?
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Which surface of epithelial cells may contain cilia or microvilli?
Which surface of epithelial cells may contain cilia or microvilli?
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What is a primary function of simple squamous epithelium?
What is a primary function of simple squamous epithelium?
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Which epithelial tissue is composed of multiple layers with only the basal layer in contact with the basement membrane?
Which epithelial tissue is composed of multiple layers with only the basal layer in contact with the basement membrane?
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Which epithelial tissue lines the kidney tubules?
Which epithelial tissue lines the kidney tubules?
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Which layer of the basement membrane contains laminin and collagen?
Which layer of the basement membrane contains laminin and collagen?
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Which function is NOT associated with epithelial tissues?
Which function is NOT associated with epithelial tissues?
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Which type of epithelial tissue is designed for areas that experience stretching?
Which type of epithelial tissue is designed for areas that experience stretching?
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Where is endothelium found?
Where is endothelium found?
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Which type of cartilage makes up the malleable part of the external ear?
Which type of cartilage makes up the malleable part of the external ear?
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Which mature connective tissue allows stretching of tissues like the elastic arteries (aorta)?
Which mature connective tissue allows stretching of tissues like the elastic arteries (aorta)?
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What is a characteristic feature of hyaline cartilage?
What is a characteristic feature of hyaline cartilage?
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Which mature connective tissue is known for being extremely tough and making up intervertebral spaces and knee joints?
Which mature connective tissue is known for being extremely tough and making up intervertebral spaces and knee joints?
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Which type of cell is predominantly found in dense irregular connective tissue?
Which type of cell is predominantly found in dense irregular connective tissue?
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What type of tissue is characterized by having a poor blood supply and slow growth?
What type of tissue is characterized by having a poor blood supply and slow growth?
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Which statement is true about fibrocartilage?
Which statement is true about fibrocartilage?
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Which connective tissue forms most of the skeleton in the embryo?
Which connective tissue forms most of the skeleton in the embryo?
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What is the primary function of glandular epithelium?
What is the primary function of glandular epithelium?
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Which of the following is an endocrine gland?
Which of the following is an endocrine gland?
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Where are simple cuboidal epithelial tissues commonly found?
Where are simple cuboidal epithelial tissues commonly found?
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Which type of extracellular matrix can be found in connective tissues?
Which type of extracellular matrix can be found in connective tissues?
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Which connective tissue cells are most numerous?
Which connective tissue cells are most numerous?
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Which of the following does NOT describe connective tissues?
Which of the following does NOT describe connective tissues?
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What do endocrine glands release directly into the bloodstream?
What do endocrine glands release directly into the bloodstream?
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What is a shared characteristic of connective tissues?
What is a shared characteristic of connective tissues?
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Which type of connective tissue is most widely distributed in the body?
Which type of connective tissue is most widely distributed in the body?
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Which cell type is responsible for making bone?
Which cell type is responsible for making bone?
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What is the primary function of adipocytes?
What is the primary function of adipocytes?
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Which type of connective tissue forms a scaffolding used by cells of lymphoid tissues such as the spleen and lymph nodes?
Which type of connective tissue forms a scaffolding used by cells of lymphoid tissues such as the spleen and lymph nodes?
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Which type of embryonic connective tissue is found in the umbilical cord?
Which type of embryonic connective tissue is found in the umbilical cord?
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What is the function of dense irregular connective tissue?
What is the function of dense irregular connective tissue?
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Study Notes
Epithelial Tissues
- Non-ciliated simple columnar epithelium:
- Exhibit elongated nuclei
- Found on highly absorptive surfaces (e.g., lining of the gastrointestinal tract)
- Microvilli increase surface area for absorption
- Goblet cells secrete mucus
- Ciliated simple columnar epithelium:
- Cilia are much larger than microvilli (up to 300 per cell)
- Cilia beat to propel fluid or material over the epithelial surface
- Found in the lining of the fallopian tubes in the female reproductive system
- Pseudostratified columnar epithelium:
- Appears to have several layers, but all cells contact the basement membrane
- Nuclei are at different levels (not columnar)
- Ciliated variety is almost exclusive to the lining of the upper respiratory tract
- Stratified cuboidal epithelium:
- Thin, usually only 2-3 cells thick
- Found in ducts of sweat glands
- Provides protection to other tissues
- Stratified columnar epithelium is very rare
- Stratified squamous epithelium:
- Keratinized variety forms the superficial layer of the skin (epidermis)
- Non-keratinized variety lines wet surfaces (e.g., mouth, esophagus, and vagina)
- Protects against abrasion, water loss, UV, and defense against microbes
- Transitional epithelium:
- Variable appearance
- Almost exclusively lines the urinary system (e.g., bladder, ureters, and urethra)
- Allows urinary organs to stretch and maintain a protective lining
Epithelia vs. Connective Tissues
- Surfaces of epithelial cells and basement membrane:
- Apical surfaces may contain cilia or microvilli
- Lateral surfaces may contain junctions
- Basal surface binds to the basement membrane
- Function of epithelia:
- Form selective barriers
- Provide secretory surfaces
- Provide protective surfaces
Classification of Epithelial Tissues
Classified by Shape of Surface Cells
- Squamous = flat
- Cuboidal = cube-shaped
- Columnar = tall column
- Transitional = shape varies with tissue stretching (changes shape)
Classified by Arrangement of Cells into Layers
- Simple: One layer, all cells in contact with basement membrane
- Pseudostratified: Appears to have layers, but all cells contact the basement membrane
- Stratified: Two or more layers, only basal layer in contact with basement membrane
Simple Squamous Epithelium
- Found lining surfaces involved in passive transport (diffusion)
- Examples: gases (lungs), liquids (walls of blood capillaries), epithelial layer of serous membranes (mesothelium), and lining of pleural, pericardial, and peritoneal cavities (visceral/parietal layers)
Simple Cuboidal Epithelium
- Functions in secretion and absorption
- Usually lines small ducts and tubules
- Examples: covers the surface of the ovary, lines kidney, salivary, and pancreatic tubules
Basement Membrane
- Consists of two extracellular layers:
- Basal lamina: contains laminin and collagen
- Reticular lamina: contains fibroblasts that secrete collagen
Connective Tissues
- Dense irregular connective tissue:
- Consists predominantly of fibroblasts and freely branching elastic fibers
- Allows stretching of certain tissues like the elastic arteries (e.g., aorta)
- Cartilage:
- Tissue with poor blood supply that grows slowly
- Hyaline (glass-like) cartilage is the most abundant type
- Covers the ends of long bones and parts of the ribs, nose, trachea, bronchi, and larynx
- Provides a smooth surface for joint movement
- Fibrocartilage:
- Consists of chondrocytes located in a threadlike network of elastic fibers
- Makes up the malleable part of the external ear and the epiglottis
- Elastic cartilage:
- With thick bundles of collagen fibers, is a very strong, tough cartilage
- Supports the huge loads up and down the long axis of the body
- Makes up the intervertebral spaces and the knee joints
Histology
- Histology is the science that deals with the study of tissues
- Pathologists specialize in laboratory studies of cells and tissues for diagnoses
Cell Junctions
- Contact points between membranes of tissue cells
- Five main types: tight junctions, adherens, desmosomes, hemidesmosomes, and gap junctions
Adherens Junctions
- Contain plaque protein which anchors membrane proteins to cytoskeleton
- Cadherins: transmembrane glycoproteins join adjacent cells
- Form adhesion belts around cells
- Helps resist cells separating under mechanical stress (e.g., during peristalsis)
Tight Junctions
- Web-like strands of transmembrane proteins
- Fuse together at the outer surfaces of cells
- Seal passageways between cells
- Found in the stomach, intestines, and bladder
- Prevent leakage and stop substances from passing between cells
Desmosomes and Hemidesmosomes
Desmosomes
- Like adherens, contain plaque protein and Cadherins
- Plaque attaches to intermediate filaments in cells (Keratin)
- Intermediate span cells, providing stability
Hemidesmosomes
- Do not link adjacent cells
- Contain Integrin transmembrane glycoproteins (not cadherins) which attach to intermediate filaments inside cells
- Anchor to the basement membrane by binding to Laminin
Four Basic Tissue Types
- Epithelial:
- Covers body surfaces and lines hollow organs, body cavities, ducts, and forms glands
- Connective:
- Protects, supports, and binds organs
- Stores energy as fat and provides immunity
- Muscular:
- Generates the physical force needed to make body structures move and generate body heat
- Nervous:
- Detects changes in the body and responds by generating nerve impulses
Cytoskeleton
- Network of protein filaments throughout the cytosol
- Provides structural support for the cell
- Three types:
- Actin/Myosin: generates movement and mechanical support
- Intermediate filaments: stabilize organelle position and attach cells together
- Microtubules: hollow tubes - TUBULIN, determines cell shape, and movement of organelles and vesicles
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Description
Learn about the definition and types of tissues, as well as the different types of cell junctions in this biology quiz. Understand the importance of histology in diagnosing diseases.