Biology Scientific Method Quiz
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Questions and Answers

Inductive reasoning is ideally used for testing biological hypotheses.

False (B)

What is the process called where specific observations are synthesized to produce a general statement?

Induction

The process of making predictions based on a biological hypothesis is part of __________ science.

hypothesis-testing

Match the following concepts with their definitions:

<p>Descriptive science = Observations and measurements made without experimental application Biological hypothesis = A proposed explanation to be tested Prediction = A statement about what will happen in an experiment Inference = A conclusion drawn from data analysis</p> Signup and view all the answers

What is a major advantage of manipulative studies over observational studies?

<p>They better control for confounding variables. (C)</p> Signup and view all the answers

Confounding variables are always known to researchers.

<p>False (B)</p> Signup and view all the answers

What is the purpose of a control in an experimental procedure?

<p>To minimize the effects of confounding variables.</p> Signup and view all the answers

In a manipulative study, the researcher actively changes the ______ variable.

<p>independent</p> Signup and view all the answers

Match the following terms to their definitions:

<p>Inferential Strength = The measure of how strongly results support conclusions Observational Study = A study where variables are measured without manipulation Confounding Variable = An unknown variable that may influence the results Control = An experimental procedure designed to minimize confounding effects</p> Signup and view all the answers

What is the primary aim of the scientific method?

<p>To acquire knowledge based on evidence (C)</p> Signup and view all the answers

Hypotheses can be proven to be true in the scientific method.

<p>False (B)</p> Signup and view all the answers

What are the two types of science discussed?

<p>Descriptive and hypothesis-testing</p> Signup and view all the answers

The scientific method is an approach to knowledge acquisition that relies on _____ and experimentation.

<p>evidence</p> Signup and view all the answers

What role do controls play in an experiment?

<p>They help address confounding variables. (B)</p> Signup and view all the answers

Hypothesis-testing science is primarily focused on observing patterns without manipulating variables.

<p>False (B)</p> Signup and view all the answers

What is the key difference between a hypothesis and a theory?

<p>A hypothesis is a proposed explanation, while a theory is a well-substantiated explanation.</p> Signup and view all the answers

What is one potential consequence of folate deficiency in pregnant women?

<p>Serious neural defects in the developing fetus (D)</p> Signup and view all the answers

Melanin primarily evolved to protect against skin cancer caused by UV radiation.

<p>False (B)</p> Signup and view all the answers

Melanin helps reduce the loss of folate due to _____-induced degradation.

<p>UV</p> Signup and view all the answers

What is another name that could better describe 'hypothesis testing' according to recent insights?

<p>Statistical inference (A)</p> Signup and view all the answers

Researchers seeking to confirm their existing beliefs are conducting legitimate science.

<p>False (B)</p> Signup and view all the answers

What must scientists strive to be to ensure their findings are unbiased?

<p>objective</p> Signup and view all the answers

Knowledge acquisition requires researchers to be _____, guided by reason and employing the scientific method.

<p>rational</p> Signup and view all the answers

Match the following terms with their descriptions:

<p>Falsifiable hypothesis = A hypothesis that can be proven false Statistical inference = Determining the validity of observed patterns Pseudo-science = Studies that only confirm beliefs Methodologically materialistic = Focusing only on the material world</p> Signup and view all the answers

Which of the following describes the approach of a researcher who aims to disprove a hypothesis?

<p>They show that at least one deductive prediction is false. (D)</p> Signup and view all the answers

Observations that suggest a flat Earth can also support the idea of a spherical Earth.

<p>True (A)</p> Signup and view all the answers

What should researchers do when they find evidence that contradicts their hypothesis?

<p>modify or reject their hypothesis</p> Signup and view all the answers

What defines a scientific theory?

<p>An explanation of a natural phenomenon that has survived multiple tests (B)</p> Signup and view all the answers

Humans and chimpanzees do not share a common ancestor.

<p>False (B)</p> Signup and view all the answers

What role does melanin play in human skin?

<p>Melanin absorbs UV light and protects against UV-induced DNA damage.</p> Signup and view all the answers

The hypothesis suggests that human skin color variation evolved from selection for increased __________ in areas of high UV exposure.

<p>melanin</p> Signup and view all the answers

Match the following concepts to their descriptions:

<p>Theory = Explanation of natural phenomena with extensive testing Hypothesis = Proposed explanation to be tested Evolution = Change in species over time Melanin = Pigment in skin that absorbs UV light</p> Signup and view all the answers

Why did early humans lose much of their body hair?

<p>To enhance evaporative cooling (C)</p> Signup and view all the answers

Dark skin offers more protection from UV-induced DNA mutations than lighter skin.

<p>True (A)</p> Signup and view all the answers

What is the impact of UV light on DNA?

<p>UV light can cause DNA mutations.</p> Signup and view all the answers

Flashcards

Scientific Method

A way of acquiring knowledge based on evidence collected through observation and experimentation.

Descriptive Science

Describes patterns in the natural world.

Hypothesis-Testing Science

Explains patterns observed in the natural world.

Hypothesis vs. Prediction vs. Theory

These are different stages in the scientific process: Hypotheses are proposed explanations, predictions are specific statements about expected results, and theories are well-supported explanations.

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Science vs. Non-science

Science relies on evidence and the scientific method. Non-science doesn't have these criteria.

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Confounding Variables

Unwanted factors that can influence the results of an experiment.

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Controls

Maintaining aspects of an experiment constant to isolate the effects of the variables being studied.

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Inferential Strength and Extrapolation (studies)

The ability to apply results from a study to broader scenarios and how strong conclusions can be drawn from the specific to broader contexts.

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Primary production

The process by which plants and algae produce their own food using sunlight.

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Limiting nutrient

A nutrient that is present in a quantity that restricts the growth of an organism (like algae).

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Hypothesis

A testable statement that explains an observation and is potentially true.

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Inductive reasoning

Using specific observations to make a broader or general conclusion .

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Scientific Theory

A well-supported explanation of an aspect of the natural world, repeatedly tested and accepted as scientific knowledge.

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Human skin color evolution

The change in human skin color due to environmental pressures, like UV radiation.

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UV radiation

Sunlight's ultraviolet rays that can cause skin damage.

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Melanin

A pigment produced by skin cells that absorbs UV radiation.

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Skin Cancer

A disease caused by DNA mutations in skin cells, typically due to UV exposure.

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Common ancestor

A shared ancestor of two or more different species.

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Evolutionary selection

The process where organisms with traits better suited to their environment are more likely to survive and reproduce, passing those traits to their offspring.

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Falsifiable hypotheses

Hypotheses formulated in a way that allows them to be proven wrong based on evidence.

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Deductive predictions

Predictions logically derived from a hypothesis, which can be tested.

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Statistical inference

Using statistical methods to determine if observed patterns are real or due to chance.

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Rationality (in science)

Using reason and logic as the primary guide for scientific inference based on evidence.

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Skepticism in science

Continuously questioning hypotheses and evidence to ensure validity.

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Objective research

Unbiased research free from preconceived notions, beliefs, or external influences.

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Materialism in science

Limiting explanations to natural causes or phenomena.

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Manipulative Study

A study where researchers actively change an independent variable to observe its effect on a dependent variable.

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Inferential Strength

How strongly the results of a study support the conclusions.

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Control (in experiment)

An experimental procedure or treatment used to minimize the impact of confounding variables.

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Independent Variable

The variable that researchers actively change in an experiment.

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Folate's Role in Pregnancy

Folate, a crucial nutrient for DNA synthesis, is particularly important during pregnancy to support the rapid DNA replication in the developing fetus.

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Folate Deficiency Consequences

Folate deficiency during pregnancy can lead to anemia in the mother, serious neural defects in the fetus, and increased risk of miscarriage.

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Melanin and UV-induced Folate Breakdown

Melanin pigmentation protects against UV-induced folate breakdown, which is especially important to prevent deficiency during pregnancy.

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Melanin: Weak Cancer Protection

While melanin protects against UV-induced folate breakdown, its role in protecting against skin cancer is likely minimal due to the delayed onset of the disease.

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Skin Cancer: Weak Selective Pressure

Skin cancer generally appears late in life, after reproductive age, and is usually not fatal. This makes it a weak selective pressure for increased melanin production.

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Study Notes

The Scientific Method

  • Biology is the study of the structure and behaviour of the natural world through observation and experimentation.
  • The scientific method is an approach to acquiring knowledge based on evidence (data from observation and experimentation).

Learning Objectives

  • Define science and the scientific method, and explain its importance.
  • Distinguish different types of science and reasoning, and outline their roles in the scientific method.
  • Differentiate between hypothesis, prediction and theory.
  • Explain how science rejects hypotheses, not proves them.
  • Summarize characteristics that distinguish science from non-science.
  • Explain confounding variables and the role of controls in addressing them.
  • Explain inferential strength and extrapolation, and how these relate to observational and manipulative studies.
  • Outline the four requirements for science to lead to knowledge acquisition.
  • Demonstrate understanding through a case study on human skin colour evolution.

Definitions Continued

  • Biology: The intellectual and practical activity encompassing the systematic study of the structure and behaviour of the natural world through both observation and experimentation.
  • Scientific Method: An approach to knowledge acquisition that ensures understanding is based on evidence (data acquired from observation and experimentation).

Two Types of Science

  • Descriptive science: Characterizes patterns in the natural world.
  • Hypothesis-testing science: Tests causal explanations for existing patterns in the natural world.

Importance of Both Types

  • Descriptive science provides the basis for hypothesis-testing (identifying patterns, suggesting explanations).
  • Hypothesis-testing science interprets patterns and guides the search for further patterns.

Example: Eutrophication

  • Descriptive study: Reveals a pattern (e.g., primary production increasing with potassium concentration).
  • Hypothesis: Potassium is a limiting nutrient, increasing its availability leads to increased algal growth.
  • Experimental test: Manipulating potassium concentration shows no effect.
  • Rejection of hypothesis: Identifying other potential factors that may impact primary production.

The Scientific Method (Diagrammatic Summary)

  • Descriptive science + Induction → Biological hypothesis → Deduction → Prediction → Study & Data → Inference → Conclusions (support or reject hypothesis)

Induction

  • Specific observations (patterns) are synthesized to create a general statement (conclusion).
  • Inductive reasoning can be the source of biological hypotheses, but it is not ideal for testing them.
  • If all axioms are true, then the conclusion can still be false.

Deduction in Hypothesis-Testing Science

  • Hypothesis: A causal explanation of a pattern.
  • Prediction: A statement of what should be observed if the hypothesis is true.
  • A prediction only exists within the context of a specific hypothesis and study.
  • The scientific method applies deduction to generate predictions and test hypotheses.

Deduction (Syllogism)

  • A form of reasoning from one or more general statements (premises) to a logical conclusion.
  • If the premises are true, the conclusion must also be true.
  • For example: Premise 1: All birds have feathers Premise 2: All robins are birds Conclusion: Therefore, all robins have feathers

Deduction in Hypothesis Testing

  • With respect to testing a hypothesis, predictions must follow deductively from the hypothesis.
  • Predictions can be formalized as if/then statements. (If hypothesis X is true and a study of type Y is performed, then result Z will be observed.)

What Makes a Scientific Hypothesis

  • A scientific hypothesis must be causal and refutable in principle, having possible outcomes inconsistent with it, which means it is falsifiable.
  • It cannot be possible to conclusively prove a hypothesis, only falsify. A hypothesis that cannot be falsified is not a scientific hypothesis.
  • Example of an unfalsifiable claim: "Life arose from divine creation."

Science Proceeds by Falsifying Hypotheses

  • Popper argued that science eliminates hypotheses, not proves them.
  • One cannot definitively prove a hypothesis; any observation supporting a hypothesis does not automatically prove it true (it can be an outcome of an alternative cause).
  • Disproving a prediction falsifies a hypothesis.
  • Example: If the garden is not wet, and you predict that if it rained last night the garden will be wet, then the hypothesis 'It rained last night' is falsified.

A Logical Fallacy: You Can't Prove a Hypothesis

  • One cannot prove a hypothesis by observing a supported prediction (it could stem from a different cause).

Observational vs. Manipulative Studies

  • Observational studies observe or measure characteristics without altering the system.
  • Manipulative studies (experiments) actively change and measure some aspect(s) of a system and compare this to a control.
  • Inferential strength is greater in manipulative studies, due to better control of confounding variables.

Confounding Variables

  • Confounding variables are other factors that may influence the variable being studied and can create false associations and incorrect conclusions.
  • Manipulative studies help reduce confounding variables.

Example: Effect of an Oncolytic Virus

  • Biological questions (e.g., Can a tumour-killing virus effectively reduce tumour growth rates in vivo)?
  • Procedure or experimental design (e.g., Inject a virus suspension into spontaneous tumour mouse model and track growth)
  • Design and implementation of appropriate controls (comparison group to rule out other factors that could affect growth).

All Else is Often Not Equal: Extrapolation

  • Studies are often conducted on model systems which are smaller or simpler than the actual system of interest and require extrapolation.
  • Extracting inferences from model systems assumes that the models behave similarly.
  • The amount of extrapolation required influences the strength of inferences and conclusions.

Common Types of Extrapolation

  • Interspecies (e.g., using rat models for human health study).
  • From indicators to system properties (e.g., using gene expression as a proxy for biological processes).
  • Spatial and temporal scales
  • In vitro to in vivo extrapolation

Hypotheses and Predictions

  • A hypothesis is a statement about possible causes of a pattern.
  • A prediction details the expected outcome of a study if the hypothesis is correct.
  • Observed patterns support, but do not prove, a hypothesis

Hypothesis vs. Theory

  • A theory is a hypothesis that has withstood numerous attempts at falsification and is therefore an accepted explanation.

Case Study: Skin Colour Evolution in Humans

  • A summary of geographic variation in human skin colour.
  • Possible hypotheses for the evolutionary causes of these variations are proposed, such as evolutionary selection for reduced UV-induced DNA degradation and increased vitamin D synthesis.
  • A case study is presented to explain the evolution of human skin colour.

Statistical Hypothesis Testing

  • Determines if a pattern in results is real or due to chance variation.
  • Important for assessing the validity of observed patterns.
  • Descriptive science often involves statistical hypothesis testing.
  • Statistical inference is used to determine the presence of predicted patterns and support/reject hypotheses based on that evidence.

Science vs. Pseudo-science

  • Pseudo-science is a study that seeks only to confirm preconceived beliefs, without critically evaluating the evidence.
  • Popper called such studies pseudo-science.

Rationality and Skepticism in Scientific Inquiry

  • Science relies on reason and evidence-based inferences.
  • Scientists constantly question and evaluate hypotheses and evidence.

Required Characteristics for Scientific Inquiry

  • Be rational.
  • Be skeptical.
  • Objectively evaluate hypotheses and evidence.
  • Avoid making assumptions or drawing conclusions based on irrelevant or non-testable factors (e.g., supernatural causes).

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Description

Test your understanding of the scientific method and its applications in biology. This quiz covers hypotheses, experimental procedures, and the advantages of manipulative studies over observational studies. Challenge your knowledge of key concepts and definitions relevant to biological research.

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