Podcast
Questions and Answers
What is the biggest job RNA and DNA have inside of cells?
What is the biggest job RNA and DNA have inside of cells?
Making proteins inside the cells.
What is the second thing RNA and DNA do?
What is the second thing RNA and DNA do?
They make up our genes.
What do all living things have in common?
What do all living things have in common?
All living things have DNA.
What are the building blocks (monomers) of nucleic acids?
What are the building blocks (monomers) of nucleic acids?
What are the 4 different nitrogen bases that make up a DNA strand?
What are the 4 different nitrogen bases that make up a DNA strand?
How are nucleotides bonded to make RNA?
How are nucleotides bonded to make RNA?
How is DNA put together?
How is DNA put together?
Why do scientists think we have DNA?
Why do scientists think we have DNA?
What are 3 main differences between RNA and DNA?
What are 3 main differences between RNA and DNA?
What is ATP?
What is ATP?
What does ATP do?
What does ATP do?
Proteins are built by?
Proteins are built by?
What do we get when we eat food and what do we do then?
What do we get when we eat food and what do we do then?
What are three components of amino acids that are the same?
What are three components of amino acids that are the same?
How many amino acids are there?
How many amino acids are there?
What part is different in amino acids?
What part is different in amino acids?
Describe how two or more amino acids are bonded together.
Describe how two or more amino acids are bonded together.
When you bond a bunch of amino acids together, the molecule is called a ______ and they are held together by ______ bonds. These molecules are usually ______ of amino acids long.
When you bond a bunch of amino acids together, the molecule is called a ______ and they are held together by ______ bonds. These molecules are usually ______ of amino acids long.
What is the difference between a polypeptide and a protein?
What is the difference between a polypeptide and a protein?
What factors determine how a polypeptide is folded?
What factors determine how a polypeptide is folded?
The shape of a polypeptide determines its?
The shape of a polypeptide determines its?
What happens if a polypeptide is 'denatured'?
What happens if a polypeptide is 'denatured'?
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Study Notes
RNA and DNA Functions
- DNA and RNA are essential for protein synthesis within cells.
- DNA provides the genetic instructions; RNA acts as the worker carrying those instructions.
Genetic Inheritance
- RNA and DNA contribute to the formation of genes, which are hereditary units.
- Individual DNA is inherited from both parents, creating a unique combination from each.
Universal Presence of DNA
- All living organisms possess DNA as a fundamental component of life.
Building Blocks of Nucleic Acids
- Nucleic acids, DNA and RNA, are constructed from monomers called nucleotides.
Nitrogen Bases in DNA
- DNA contains four nitrogen bases: adenine, cytosine, guanine, and thymine.
- In RNA, uracil replaces thymine found in DNA.
Nucleotide Bonding in RNA
- Nucleotides bond through a dehydration reaction, resulting in covalent bonds between pentose sugars and phosphates.
DNA Structure
- DNA is assembled with its nucleotides forming hydrogen bonds between specific bases: adenine pairs with thymine, and guanine pairs with cytosine.
Evolution of DNA
- Scientists hypothesize DNA evolved from RNA, with RNA initially encoding information before the formation of double-stranded DNA.
- The backbone of DNA is composed of alternating sugar and phosphate groups.
Differences between RNA and DNA
- RNA has uracil, is single-stranded, and is found throughout the cell.
- DNA has thymine, is a double helix structure, and is localized in the nucleus.
ATP Structure and Function
- ATP, or adenosine triphosphate, consists of three phosphate groups, ribose, and adenine.
- Serves as the primary energy currency of cells.
Protein Synthesis
- Proteins are constructed from amino acids, which are their basic building blocks.
- Dietary sources provide amino acids, which are broken down to form new proteins.
Amino Acid Structure
- Amino acids share three common components:
- Alpha carbon with a hydrogen,
- Amino group with nitrogen,
- Carboxyl group with carbon and oxygen/hydrogen.
Amino Acid Count
- There are a total of 20 different amino acids.
Variation in Amino Acids
- The distinctive feature of each amino acid is the R group, which provides different chemical properties.
Polypeptide Formation
- Amino acids bond through dehydration synthesis with the assistance of ribosomes during protein synthesis.
- The resulting structure from this process is a polypeptide, held together by peptide bonds.
Distinction Between Polypeptide and Protein
- A polypeptide is a simple chain of amino acids.
- A protein consists of one or more polypeptides folded into a specific three-dimensional shape.
Polypeptide Folding
- Folding of polypeptides is dictated by the sequence of amino acids and the properties of their R groups.
- The specific shape is determinant for the protein's function.
Denaturation of Polypeptides
- Extreme temperatures or pH levels can lead to denaturation, rendering the polypeptide nonfunctional.
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